Nature Search

Polychlorinated Biphenyls in the Global Ecosystem

R. W. RISEBROUGH
P. RIECHE
M. N. KIRVEN
Research14 Dec 1968
Nature

Volume: 220, P: 1098-1102
Sizing up beta cells made from stem cells

A thorough study of lab-made pancreatic beta cells reveals their differences from primary cells.

Kim-Vy Nguyen-Ngoc
Matthew Wortham
Maike Sander
News & Views14 Mar 2022
Nature Biotechnology

Volume: 40, P: 1006-1008
Implications of the late Palaeozoic oxygen pulse for physiology and evolution

Jeffrey B. Graham
Nancy M. Aguilar
Carl Gans
Research11 May 1995
Nature

Volume: 375, P: 117-120
Demonstration of Super-X divertor exhaust control for transient heat load management in compact fusion reactors

Managing power exhaust in fusion reactors is a key challenge, especially in compact designs for cost-effective commercial energy. This study shows how alternative divertor configurations improve exhaust control, enhance stability, absorb transients and enable independent plasma regulation.

B. Kool
K. Verhaegh
V. Zamkovska
ResearchOpen Access05 Sept 2025
Nature Energy

Volume: 10, P: 1116-1131
Placental alkaline phosphatase in Hominidae

GEORGE J. DOELLGAST
KURT BENIRSCHKE
Research01 Aug 1979
Nature

Volume: 280, P: 601-602
Depletion of protein kinase C (PKC) by 12-O-tetradecanoylphorbol-13-acetate (TPA) enhances platinum drug sensitivity in human ovarian carcinoma cells

S Isonishi
K Ohkawa
S B Howell
ResearchOpen Access10 Dec 1999
British Journal of Cancer

Volume: 82, P: 34-38
Human pluripotent reprogramming with CRISPR activators

CRISPRa is an attractive tool for cellular reprogramming due to its multiplexing capacity and direct targeting of genomic loci. Here the authors demonstrate the reprogramming of human fibroblasts into iPSCs, which is enhanced by targeting a conserved Alu-motif.

Jere Weltner
Diego Balboa
Timo Otonkoski
ResearchOpen Access06 Jul 2018
Nature Communications

Volume: 9, P: 1-12
Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells

Pancreatic islets derived from stem cells are benchmarked against primary cells.

Diego Balboa
Tom Barsby
Timo Otonkoski
ResearchOpen Access03 Mar 2022
Nature Biotechnology

Volume: 40, P: 1042-1055
A communal catalogue reveals Earth’s multiscale microbial diversity

As phase 1 of the Earth Microbiome Project, analysis of 16S ribosomal RNA sequences from more than 27,000 environmental samples delivers a global picture of the basic structure and drivers of microbial distribution.

Luke R. Thompson
Jon G. Sanders
Hongxia Zhao
ResearchOpen Access01 Nov 2017
Nature

Volume: 551, P: 457-463
Mammal responses to global changes in human activity vary by trophic group and landscape

Analysing camera-trap data of 163 mammal species before and after the onset of COVID-19 lockdowns, the authors show that responses to human activity are dependent on the degree to which the landscape is modified by humans, with carnivores being especially sensitive.

A. Cole Burton
Christopher Beirne
Roland Kays
ResearchOpen Access18 Mar 2024
Nature Ecology & Evolution

Volume: 8, P: 924-935
The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α

The TYK2 gene is associated with development of type 1 diabetes. Here the authors show that TYK2 regulates β-cell development, but at the same time TYK2 inhibition in the islets prevents IFNα responses and enhances their survival against CD8⁺ T-cell cytotoxicity; representing a potent therapeutic target to halt T1D progression.

Vikash Chandra
Hazem Ibrahim
Timo Otonkoski
ResearchOpen Access26 Oct 2022
Nature Communications

Volume: 13, P: 1-16
Globally invariant metabolism but density-diversity mismatch in springtails

Springtails are omnipresent soil arthropods, vital for ecosystems. In the first global assessment of springtails, this study shows a 20-fold biomass difference between the tundra and the tropics, with distinct temperature-related patterns for diversity and metabolism that suggest climate change may restructure the functioning of soil biodiversity.

Anton M. Potapov
Carlos A. Guerra
Stefan Scheu
ResearchOpen Access07 Feb 2023
Nature Communications

Volume: 14, P: 1-13
The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A

Beucher et al. show that the promoter of lncRNA HASTER is a cis-regulatory feedback element that stabilizes HNF1A concentrations.

Anthony Beucher
Irene Miguel-Escalada
Jorge Ferrer
ResearchOpen Access06 Oct 2022
Nature Cell Biology

Volume: 24, P: 1528-1540
Efficient generation of energetic ions in multi-ion plasmas by radio-frequency heating

Triggering and sustaining fusion reactions — with the goal of overall energy production — in a tokamak plasma requires efficient heating. Radio-frequency heating of a three-ion plasma is now experimentally shown to be a potentially viable technique.

Ye. O. Kazakov
J. Ongena
I. Zychor
Research19 Jun 2017
Nature Physics

Volume: 13, P: 973-978
A control oriented strategy of disruption prediction to avoid the configuration collapse of tokamak reactors

Confining plasma and managing disruptions in tokamak devices is a challenge. Here the authors demonstrate a method predicting and possibly preventing disruptions and macroscopic instabilities in tokamak plasma using data from JET.

Andrea Murari
Riccardo Rossi
Michela Gelfusa
ResearchOpen Access18 Mar 2024
Nature Communications

Volume: 15, P: 1-19
Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

Elevated MYC levels can sensitize tumor cells to apoptosis. In this study, the authors demonstrate that AMPK activation and BCL-2/BCL-X_L inhibition have a synergistic effect on apoptosis, and that together with anti PD-1 therapy they can suppress Myc-driven mammary tumor growth.

Heidi M. Haikala
Johanna M. Anttila
Juha Klefström
ResearchOpen Access06 Feb 2019
Nature Communications

Volume: 10, P: 1-17
Publisher Correction: Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

Heidi M. Haikala
Johanna M. Anttila
Juha Klefström
Amendments and CorrectionsOpen Access20 Feb 2019
Nature Communications

Volume: 10, P: 1
Prehistorical and historical declines in Caribbean coral reef accretion rates driven by loss of parrotfish

Fishing of keystone herbivores such as parrotfish is thought to negatively impact corals. Here, Cramer and colleagues analyse the sedimentary record for the last 3,000 years from three coral reef sites in the Caribbean and show that indeed coral declines are linked to parrotfish declines.

Katie L. Cramer
Aaron O’Dea
Richard D. Norris
ResearchOpen Access23 Jan 2017
Nature Communications

Volume: 8, P: 1-8
Enhanced performance in fusion plasmas through turbulence suppression by megaelectronvolt ions

Experiments at the Joint European Torus tokamak show improved thermal ion confinement in the presence of highly energetic ions and Alfvénic instabilities in the plasma.

S. Mazzi
J. Garcia
I. Zychor
Research30 Jun 2022
Nature Physics

Volume: 18, P: 776-782
Ocean deoxygenation linked to ancient mesopelagic fish decline

Historical phases of ocean oxygen minimum are associated with near extinctions of mesopelagic fish, suggesting risks of future deoxygenation to marine fisheries due to warming, according to an analysis of a fish otolith record from a Mediterranean sediment core.

Sven Pallacks
Patrizia Ziveri
Richard D. Norris
ResearchOpen Access28 Jul 2025
Communications Earth & Environment

Volume: 6, P: 1-9
Primate-specific ZNF808 is essential for pancreatic development in humans

Loss-of-function mutations in primate-specific ZNF808 cause pancreatic agenesis. Mechanistically, the loss of ZNF808 leads to the activation of the MER11 family of transposable elements in a regulatory capacity that ultimately induces a liver-specific program of gene expression during pancreatic differentiation.

Elisa De Franco
Nick D. L. Owens
Michael Imbeault
ResearchOpen Access16 Nov 2023
Nature Genetics

Volume: 55, P: 2075-2081
Kidney transplantation and the ageing immune system

As the world population continues to age, the number of elderly patients with chronic kidney disease who require a kidney transplant is increasing. In this Review, the effects of aging on the adaptive and innate immune systems are discussed, with a focus on the implications of age-related changes in the immune system on kidney transplantation and immunosuppression in elderly patients.

Dianne McKay
Julie Jameson
Reviews13 Nov 2012
Nature Reviews Nephrology

Volume: 8, P: 700-708
Divertor shaping with neutral baffling as a solution to the tokamak power exhaust challenge

Power exhaust is one of the biggest challenges stopping fusion energy. This article shows experimental evidence for strategically shaping the power exhaust region as a solution to this challenge, utilising physics understanding to strike a balance between engineering complexity and power exhaust benefits, consistent with reduced models and simulations.

Kevin Verhaegh
James Harrison
V. Zamkovska
ResearchOpen Access23 May 2025
Communications Physics

Volume: 8, P: 1-15
Averting biodiversity collapse in tropical forest protected areas

Analysis of changes in functional groups of species and potential drivers of environmental change for protected areas across the world’s major tropical regions reveals large variation between reserves that have been effective and those experiencing an erosion of biodiversity, and shows that environmental changes immediately outside reserves are nearly as important as those inside in determining their ecological fate.

William F. Laurance
D. Carolina Useche
Franky Zamzani
Research25 Jul 2012
Nature

Volume: 489, P: 290-294
Conventional taxonomy obscures deep divergence between Pacific and Atlantic corals

Hironobu Fukami
Ann F. Budd
Nancy Knowlton
Research26 Feb 2004
Nature

Volume: 427, P: 832-835
Disruption prediction with artificial intelligence techniques in tokamak plasmas

Tokamak plasmas are prone to sudden collapses that terminate the nuclear fusion reactions. This perspective discusses the prediction of these so-called disruptions with artificial intelligence techniques.

J. Vega
A. Murari
I. Zychor
Reviews06 Jun 2022
Nature Physics

Volume: 18, P: 741-750
White Band Disease (type I) of Endangered Caribbean Acroporid Corals is Caused by Pathogenic Bacteria

David I. Kline
Steven V. Vollmer
ResearchOpen Access14 Jun 2011
Scientific Reports

Volume: 1, P: 1-5
A quasi-monoenergetic short time duration compact proton source for probing high energy density states of matter

J. I. Apiñaniz
S. Malko
L. Volpe
ResearchOpen Access25 Mar 2021
Scientific Reports

Volume: 11, P: 1-11
Ecological modeling, biogeography, and phenotypic analyses setting the tiger cats’ hyperdimensional niches reveal a new species

Tadeu G. de Oliveira
Lester A. Fox-Rosales
Flávio H. G. Rodrigues
ResearchOpen Access29 Jan 2024
Scientific Reports

Volume: 14, P: 1-19
Viscosin-like lipopeptides from frog skin bacteria inhibit Aspergillus fumigatus and Batrachochytrium dendrobatidis detected by imaging mass spectrometry and molecular networking

Christian Martin H.
Roberto Ibáñez
Marcelino Gutiérrez
ResearchOpen Access28 Feb 2019
Scientific Reports

Volume: 9, P: 1-11
p73 is required for appropriate BMP-induced mesenchymal-to-epithelial transition during somatic cell reprogramming

Marta Martin-Lopez
Laura Maeso-Alonso
Maria C Marin
ResearchOpen Access07 Sept 2017
Cell Death & Disease

Volume: 8, P: e3034
The Forest Observation System, building a global reference dataset for remote sensing of forest biomass

Dmitry Schepaschenko
Jérôme Chave
Irié Casimir Zo-Bi
ResearchOpen Access10 Oct 2019
Scientific Data

Volume: 6, P: 1-11

Search

Polychlorinated Biphenyls in the Global Ecosystem

Sizing up beta cells made from stem cells

Implications of the late Palaeozoic oxygen pulse for physiology and evolution

Demonstration of Super-X divertor exhaust control for transient heat load management in compact fusion reactors

Placental alkaline phosphatase in Hominidae

Depletion of protein kinase C (PKC) by 12-O-tetradecanoylphorbol-13-acetate (TPA) enhances platinum drug sensitivity in human ovarian carcinoma cells

Human pluripotent reprogramming with CRISPR activators

Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells

A communal catalogue reveals Earth’s multiscale microbial diversity

Mammal responses to global changes in human activity vary by trophic group and landscape

The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α

Globally invariant metabolism but density-diversity mismatch in springtails

The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A

Efficient generation of energetic ions in multi-ion plasmas by radio-frequency heating

A control oriented strategy of disruption prediction to avoid the configuration collapse of tokamak reactors

Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

Publisher Correction: Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

Prehistorical and historical declines in Caribbean coral reef accretion rates driven by loss of parrotfish

Enhanced performance in fusion plasmas through turbulence suppression by megaelectronvolt ions

Ocean deoxygenation linked to ancient mesopelagic fish decline

Primate-specific ZNF808 is essential for pancreatic development in humans

Kidney transplantation and the ageing immune system

Divertor shaping with neutral baffling as a solution to the tokamak power exhaust challenge

Averting biodiversity collapse in tropical forest protected areas

Conventional taxonomy obscures deep divergence between Pacific and Atlantic corals

Disruption prediction with artificial intelligence techniques in tokamak plasmas

White Band Disease (type I) of Endangered Caribbean Acroporid Corals is Caused by Pathogenic Bacteria

A quasi-monoenergetic short time duration compact proton source for probing high energy density states of matter

Ecological modeling, biogeography, and phenotypic analyses setting the tiger cats’ hyperdimensional niches reveal a new species

Viscosin-like lipopeptides from frog skin bacteria inhibit Aspergillus fumigatus and Batrachochytrium dendrobatidis detected by imaging mass spectrometry and molecular networking

p73 is required for appropriate BMP-induced mesenchymal-to-epithelial transition during somatic cell reprogramming

The Forest Observation System, building a global reference dataset for remote sensing of forest biomass

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