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The Synthesis of Resveratrol (Thesis)

Dustin Sprouse
ResearchOpen Access20 Jul 2010
Nature Precedings

P: 1
Human ARHGEF9 intellectual disability syndrome is phenocopied by a mutation that disrupts collybistin binding to the GABA_A receptor α2 subunit

Dustin J. Hines
April Contreras
Rochelle M. Hines
ResearchOpen Access12 May 2022
Molecular Psychiatry

Volume: 27, P: 1275
Carvone derived cannabidiol enantiomers as novel anticonvulsants

Rochelle M. Hines
April Contreras
Dustin J. Hines
ResearchOpen Access24 Sept 2025
Neuropsychopharmacology

Volume: 50, P: 1970-1981
Developmental seizures and mortality result from reducing GABA_A receptor α2-subunit interaction with collybistin

The inhibitory synaptic protein collybistin (CB) and GABA_AR-α subunits are thought to interact, but strength and specificity are unclear. Here the authors study the CB–α2 interaction and show that a mouse mutated in the CB-binding region of α2 displays a loss of specific synapses and seizure.

Rochelle M. Hines
Hans Michael Maric
Stephen J. Moss
ResearchOpen Access07 Aug 2018
Nature Communications

Volume: 9, P: 1-15
Behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT_2A receptor activation

April Contreras
Matthew Khumnark
Dustin J. Hines
ResearchOpen Access21 Jan 2021
Scientific Reports

Volume: 11, P: 1-12
Human ARHGEF9 intellectual disability syndrome is phenocopied by a mutation that disrupts collybistin binding to the GABA_A receptor α2 subunit

Dustin J. Hines
April Contreras
Rochelle M. Hines
ResearchOpen Access15 Feb 2022
Molecular Psychiatry

Volume: 27, P: 1729-1741

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The Synthesis of Resveratrol (Thesis)

Human ARHGEF9 intellectual disability syndrome is phenocopied by a mutation that disrupts collybistin binding to the GABA_A receptor α2 subunit

Carvone derived cannabidiol enantiomers as novel anticonvulsants

Developmental seizures and mortality result from reducing GABA_A receptor α2-subunit interaction with collybistin

Behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT_2A receptor activation

Human ARHGEF9 intellectual disability syndrome is phenocopied by a mutation that disrupts collybistin binding to the GABA_A receptor α2 subunit

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The Synthesis of Resveratrol (Thesis)

Human ARHGEF9 intellectual disability syndrome is phenocopied by a mutation that disrupts collybistin binding to the GABAA receptor α2 subunit

Carvone derived cannabidiol enantiomers as novel anticonvulsants

Developmental seizures and mortality result from reducing GABAA receptor α2-subunit interaction with collybistin

Behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT2A receptor activation

Human ARHGEF9 intellectual disability syndrome is phenocopied by a mutation that disrupts collybistin binding to the GABAA receptor α2 subunit

Search

Quick links

Human ARHGEF9 intellectual disability syndrome is phenocopied by a mutation that disrupts collybistin binding to the GABA_A receptor α2 subunit

Developmental seizures and mortality result from reducing GABA_A receptor α2-subunit interaction with collybistin

Behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT_2A receptor activation

Human ARHGEF9 intellectual disability syndrome is phenocopied by a mutation that disrupts collybistin binding to the GABA_A receptor α2 subunit