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Advanced filters: Author: Dylan Caylor Clear advanced filters

  • CRISPR–Cas9-based saturation genome editing in a humanized mouse embryonic stem cell line was used for comprehensive functional characterization of single nucleotide variants in a region of BRCA2, and shows good agreement with existing variant classifications and high predictive power.

    • Sounak Sahu
    • Melissa Galloux
    • Shyam K. Sharan
    Research
    Nature
    Volume: 638, P: 538-545