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Showing 1–50 of 140 results

Advanced filters: Author: E Hecker Clear advanced filters

Mitochondrial RNA cytosolic leakage drives the SASP

Here the authors show that mitochondrial RNA leaks into the cytosol of senescent cells through sublethal apoptosis, driving inflammation. Blocking this pathway improves outcomes in Metabolic Dysfunction-Associated Steatohepatitis.

Stella Victorelli
Madeline Eppard
João F. Passos
ResearchOpen Access15 Dec 2025
Nature Communications

Volume: 16, P: 1-15
Adipocyte NADH dehydrogenase reverses circadian and diet-induced metabolic syndrome

Circadian clock in adipocytes maintains metabolic health by regulating mitochondrial complex I respiration.

Chelsea Hepler
Nathan J. Waldeck
Joseph Bass
ResearchOpen Access18 Feb 2026
Nature Metabolism

P: 1-13
Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors

Mohammed Shoyab
Joseph E. De Larco
George J. Todaro
Research01 May 1979
Nature

Volume: 279, P: 387-391
The ratio of circulatory levels of sphingolipids to steroids predicts asthma exacerbations

Asthma exacerbations remain hard to predict with routine tests. Here, the authors show that simple blood sphingolipid-to-steroid ratios predict five-year exacerbation risk and can underpin a practical, low-cost assay that outperforms standard clinical measures.

Yulu Chen
Pei Zhang
Jessica A. Lasky-Su
ResearchOpen Access19 Jan 2026
Nature Communications

Volume: 17, P: 1-16
Methylation of single-stranded DNA in vitro introduces new restriction endonuclease cleavage sites

BRUNO GRONENBORN
JOACHIM MESSING
Research01 Mar 1978
Nature

Volume: 272, P: 375-377
Electron microscopy of hepatitis B core antigen synthesized in E. coli

B. J. Cohen
J. E. Richmond
Research15 Apr 1982
Nature

Volume: 296, P: 677-678
Monovalent pseudo-natural products supercharge degradation of IDO1 by its native E3 KLHDC3

In targeted protein degradation, a degrader molecule brings a neosubstrate protein proximal to a hijacked E3 ligase for its ubiquitination. Here, pseudo-natural products derived from (−)-myrtanol—iDegs—are identified to inhibit and induce degradation of the immunomodulatory enzyme indoleamine-2,3-dioxygenase 1 (IDO1) by a distinct mechanism. iDegs prime apo-IDO1 ubiquitination and subsequent degradation using its native proteolytic pathway.

Elisabeth Hennes
Belén Lucas
Herbert Waldmann
ResearchOpen Access07 Jan 2026
Nature Chemistry

P: 1-12
Trabectedin plus CD13-targeted tissue factor tTF-NGR against advanced relapsed or refractory soft tissue sarcoma: translational data, clinical safety and efficacy

Kathrin Hessling
Caroline Brand
Christoph Schliemann
ResearchOpen Access19 Feb 2026
Scientific Reports

Volume: 16, P: 1-13
Analysis of Counter-Current Distribution Curves

G. G. F. NEWTON
E. P. ABRAHAM
Research12 Jan 1952
Nature

Volume: 169, P: 69
Tumour-promoting diterpene esters prevent macrophage activation

R Keller
R Keist
E Hecker
Research01 Jan 1982
British Journal of Cancer

Volume: 45, P: 144-146
Calcium transients and intramembrane charge movement in skeletal muscle fibres

L. Kovács
E. Ríos
M. F. Schneider
Research01 May 1979
Nature

Volume: 279, P: 391-396
Pheromones in the Communication of Sexual Status in Primates

R. P. MICHAEL
E. B. KEVERNE
Research25 May 1968
Nature

Volume: 218, P: 746-749
Population distribution of product states following three-body recombination in an ultracold atomic gas

Atom and ion trapping provides new tools for ultracold chemistry. Using these techniques it is possible to measure the population distribution of the product states of three-body recombination in an ultracold atomic gas.

A. Härter
A. Krükow
J. Hecker Denschlag
Research23 Jun 2013
Nature Physics

Volume: 9, P: 512-517
Retinoids block phenotypic cell transformation produced by sarcoma growth factor

GEORGE J. TODARO
JOSEPH E. DE LARCO
MICHAEL B. SPORN
Research16 Nov 1978
Nature

Volume: 276, P: 272-274
Coherent charge oscillations in a bilayer graphene double quantum dot

Graphene quantum dots promise applications for spin and valley qubits; however a demonstration of phase coherent oscillations has been lacking. Here the authors report coherent charge oscillations and measurements of coherence times in highly tuneable double quantum dots in bilayer graphene.

K. Hecker
L. Banszerus
C. Stampfer
ResearchOpen Access30 Nov 2023
Nature Communications

Volume: 14, P: 1-8
Reduced Diphosphopyridine Nucleotide-dependent Diaphorase in Foetal, Newborn and Adult Cattle

JOSEPH E. SMITH
ERNEST BEUTLER
Research13 Aug 1966
Nature

Volume: 211, P: 756-757
Fusicoccin: a New Wilting Toxin produced by Fusicoccum amygdali Del.

A. BALLIO
E. B. CHAIN
A. TONOLO
Research18 Jul 1964
Nature

Volume: 203, P: 297
Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy

Brain microvascular dysfunction occurs in Alzheimer’s disease and other taupathies. Here the authors show that soluble pathogenic tau accumulates in brain microvascular endothelial cells of P301S(PS19) mice modeling tauopathy, and that it contributes to vascular deficits in these mice.

Stacy A. Hussong
Andy Q. Banh
Veronica Galvan
ResearchOpen Access25 Apr 2023
Nature Communications

Volume: 14, P: 1-16
Haemoglobins of Adult and Foetal African Elephants

E. KLEIHAUER
I. O. BUSS
P. G. WRIGHT
Research24 Jul 1965
Nature

Volume: 207, P: 424-425
Effect of an RNA-rich Extract on Acquisition of a One-way Avoidance Response in Rats

DAVID H. MALIN
ARNOLD M. GOLUB
JAMES V. MCCONNELL
Research17 Sept 1971
Nature

Volume: 233, P: 211-212
Extant fauna of ancient carbon

M. Grachev
V. Fialkov
T. Kawai
Research09 Mar 1995
Nature

Volume: 374, P: 123-124
Tumour promoter alone induces neoplastic transformation of fibroblasts from humans genetically predisposed to cancer

Levy Kopelovich
Nancy E. Bias
Lawrence Helson
Research06 Dec 1979
Nature

Volume: 282, P: 619-621
Phorbol esters stimulate DNA synthesis and ornithine decarboxylase activity in mouse epidermal cell cultures

STUART H. YUSPA
ULRIKE LICHTI
WILLIAM KELSEY
Research01 Jul 1976
Nature

Volume: 262, P: 402-404
Mapping of an endogenous retroviral sequence to human chromosome 18

Stephen J. O'Brien
Tom I. Bonner
William G. Nash
Research05 May 1983
Nature

Volume: 303, P: 74-77
Tumour promoters induce mitotic aneuploidy in yeast

James M. Parry
Elizabeth M. Parry
J. Carl Barrett
Research19 Nov 1981
Nature

Volume: 294, P: 263-265
Spin relaxation in a single-electron graphene quantum dot

Graphene has long been considered to be a promising host for spin qubits, however a demonstration of long spin relaxation times for a potential qubit has been lacking. Here, the authors report the electrical measurement of the single-electron spin relaxation time exceeding 200 μs in a bilayer graphene quantum dot.

L. Banszerus
K. Hecker
C. Stampfer
ResearchOpen Access25 Jun 2022
Nature Communications

Volume: 13, P: 1-6
Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C

The antibody response to the SARS-CoV-2 Omicron variant is not well studied in children. Here, the authors provide an age-stratified analysis of SARS-CoV-2 neutralizing capacity of sera from children with acute or convalescent COVID-19 as well as children with multisystem inflammatory syndrome.

Juanjie Tang
Tanya Novak
Surender Khurana
ResearchOpen Access27 May 2022
Nature Communications

Volume: 13, P: 1-10
Sequencing of 16S–23S spacer in a ribosomal RNA operon of Euglena gracilis chloroplast DNA reveals two tRNA genes

L. Graf
H. Kössel
E. Stutz
Research28 Aug 1980
Nature

Volume: 286, P: 908-910
Evidence for inhibition of platelet activation in blood by a drug effect on erythrocytes

G. V. R. BORN
D. BERGQUIST
K.-E. ARFORS
Research22 Jan 1976
Nature

Volume: 259, P: 233-235
Lysozyme-induced T-suppressor cells and antibodies have a predominant idiotype

Michael A. Harvey
Luciano Adorini
Eli E. Sercarz
Research01 Oct 1979
Nature

Volume: 281, P: 594-596
Keratinocytes blocked in phorbol ester-responsive early stage of terminal differentiation by sarcoma viruses

Stuart H. Yuspa
Anne E. Kilkenny
Ulrike Lichti
Research01 Apr 1985
Nature

Volume: 314, P: 459-462
Complexity of germline and somatic DNA in Ascaris

KARL B. MORITZ
GÜNTHER E. ROTH
Research01 Jan 1976
Nature

Volume: 259, P: 55-57
Effect of a phorbol ester on a transformation-sensitive surface protein of chick fibroblasts

PETER M. BLUMBERG
PAUL E. DRIEDGER
PETER W. ROSSOW
Research02 Dec 1976
Nature

Volume: 264, P: 446-447
Symbiosis of methylotrophic bacteria and deep-sea mussels

Colleen M. Cavanaugh
Piet R. Levering
Mary E. Lidstrom
Research22 Jan 1987
Nature

Volume: 325, P: 346-348
Recombination in HIV-1

David L. Robertson
Paul M. Sharp
Beatrice H. Hahn
Research09 Mar 1995
Nature

Volume: 374, P: 124-126
Particle–hole symmetry protects spin-valley blockade in graphene quantum dots

Bilayer graphene allows the realization of electron–hole double-quantum dots that exhibit near-perfect particle–hole symmetry, in which transport occurs via the creation and annihilation of single electron–hole pairs with opposite quantum numbers.

L. Banszerus
S. Möller
C. Stampfer
Research03 May 2023
Nature

Volume: 618, P: 51-56
HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells

M Natarajan
J E Stewart Jr
C L Gladson
Research14 Nov 2005
Oncogene

Volume: 25, P: 1721-1732
Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections

Here, the authors identify interleukin-3 as a predictive marker for severity and outcome of SARS-CoV-2 infection in a multi-center, prospective study and find that patients with severe COVID-19 have reduced circulating plasmacytoid dendritic cell levels compared to non-severe COVID-19 patients.

Alan Bénard
Anne Jacobsen
Georg F. Weber
ResearchOpen Access18 Feb 2021
Nature Communications

Volume: 12, P: 1-8
Defective responses of transformed keratinocytes to terminal differentiation stimuli. Their role in epidermal tumour promotion by phorbol esters and by deep skin wounding

E K Parkinson
Reviews01 Oct 1985
British Journal of Cancer

Volume: 52, P: 479-493
DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal

How and whether histone modifications regulate distinct gene networks remains insufficiently understood. Here Cattaneo et al show that DOT1L catalyzed H3K79me2 regulates fetal chamber-specific gene expression and neonatal cardiomyocyte cell cycle withdrawal to coordinate heart development.

Paola Cattaneo
Michael G. B. Hayes
Sylvia M. Evans
ResearchOpen Access02 Dec 2022
Nature Communications

Volume: 13, P: 1-19
A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens

Polymyxins are often the last therapeutic option for multidrug-resistant (MDR) bacteria, but have suboptimal safety and efficacy. Here the authors report the discovery and development of a synthetic lipopeptide with an improved safety and efficacy against top-priority MDR Gram-negative pathogens.

Kade D. Roberts
Yan Zhu
Jian Li
ResearchOpen Access25 Mar 2022
Nature Communications

Volume: 13, P: 1-15
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

The mechanisms that lead to idiopathic pulmonary fibrosis, or lung scarring, is not clear. Victor Thannickal and his colleagues have now provided further insight by showing that induction of NOX4, an enzyme that creates reactive oxygen species, is required for the progression of the disease. Their findings suggest NOX4 as a potential target to treat this common ailment that currently has no proven treatment options.

Louise Hecker
Ragini Vittal
Victor J Thannickal
Research23 Aug 2009
Nature Medicine

Volume: 15, P: 1077-1081
Citizen science in the social sciences and humanities: the power of interdisciplinarity

Loreta Tauginienė
Eglė Butkevičienė
Baiba Prūse
ResearchOpen Access07 May 2020
Palgrave Communications

Volume: 6, P: 1-11
The hyperflexed seemingly useless tetraplegic hand: a method of surgical amelioration

W J Treanor
E Moberg
H J Buncke
Research01 Jul 1992
Spinal Cord

Volume: 30, P: 457-466
Author Correction: A genomics approach reveals insights into the importance of gene losses for mammalian adaptations

Virag Sharma
Nikolai Hecker
Michael Hiller
Amendments and CorrectionsOpen Access10 Dec 2019
Nature Communications

Volume: 10, P: 1
Ups and downs of insect populations

Analysis of the world’s longest-running insect monitoring programme finds little evidence to support steep declines in biomass across the United Kingdom over the past 50 years. Moth biomass showed a net increase, but a gradual post-1982 decline was found in certain land uses and for some moth families.

Manu E. Saunders
News & Views11 Nov 2019
Nature Ecology & Evolution

Volume: 3, P: 1616-1617
The observation of π-shifts in the Little-Parks effect in 4Hb-TaS₂

The authors report the measurement of the Little-Parks effect in the unconventional superconductor candidate 4Hb-TaS₂. They find a π-shift in the transition-temperature oscillations and an ehancement of T_c as a function of the out-of-plane field when a constant in-plane field is applied, consistent with a multi-component order parameter.

Avior Almoalem
Irena Feldman
Amit Kanigel
ResearchOpen Access30 May 2024
Nature Communications

Volume: 15, P: 1-8
Progesterone enhancement of mammary tumor development as a model of co-carcinogenesis

W E Poel
Research01 Dec 1968
British Journal of Cancer

Volume: 22, P: 867-873
Serum microRNA expression quantitative trait loci in children with asthma colocalize with asthma-related GWAS results

Julian Hecker
Anshul Tiwari
Michael McGeachie
ResearchOpen Access17 Jul 2025
npj Genomic Medicine

Volume: 10, P: 1-10
On Which Side are the Angels ?

S. E. LURIA
Correspondence17 Jan 1970
Nature

Volume: 225, P: 301-302

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