Target-oriented syntheses of natural products usually require the design of individualized routes that are tailor-made for the specific targets. Now, a strategy that runs counter to this conventional wisdom has been achieved. Exploiting a biocatalytically installed alcohol, several abiotic skeletal rearrangements have been designed to prepare three structurally disparate terpenoid natural products.
- Heping Deng
- Junhong Yang
- Hans Renata
