Conventional extracellular electrode recordings are generally limited to monitoring action potentials. But use of extracellular gold microelectrodes with microspines that are engulfed by a neuron generates efficient electrical coupling and allows detection of both action potentials and subthreshold synaptic potentials with a signal-to-noise ratio similar to that of conventional intracellular recordings.
- Aviad Hai
- Joseph Shappir
- Micha E Spira