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Author Correction: IL-17A-secreting γδ T cells promote resistance to CDK4/CDK6 inhibitors in HR⁺HER2⁻ breast cancer via CX3CR1⁺ macrophages

Giulia Petroni
Claudia Galassi
Lorenzo Galluzzi
Amendments and Corrections23 Jul 2025
Nature Cancer

P: 1
IL-17A-secreting γδ T cells promote resistance to CDK4/CDK6 inhibitors in HR⁺HER2⁻ breast cancer via CX3CR1⁺ macrophages

Petroni et al. report that the infiltration of IL-17A-secreting γδ T cells in the tumor microenvironment coupled with the accumulation of immunosuppressive macrophages is associated with resistance to CDK4/CDK6 inhibition in HR⁺HER2⁻ breast cancer.

Giulia Petroni
Claudia Galassi
Lorenzo Galluzzi
Research07 Jul 2025
Nature Cancer

P: 1-20
Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice

Cholesterol metabolism is altered in amyotrophic lateral sclerosis. The authors show that promoting cellular cholesterol excretion in a mouse model improves myelination, reduces the disease-associated oligodendrocyte response, and prolongs survival.

Ali Rezaei
Virág Kocsis-Jutka
Dieter Edbauer
ResearchOpen Access11 Apr 2025
Nature Communications

Volume: 16, P: 1-17
Twin study reveals non-heritable immune perturbations in multiple sclerosis

In monozygotic twins discordant for multiple sclerosis, the influence of genetic predisposition and environmental factors is determined using matched-pair analyses.

Florian Ingelfinger
Lisa Ann Gerdes
Burkhard Becher
ResearchOpen Access16 Feb 2022
Nature

Volume: 603, P: 152-158
High-resolution profile of neoantigen-specific TCR activation links moderate stimulation to increased resilience of engineered TCR-T cells

Mutations in cancers can generate neoepitopes which can be recognized by different specific T cell receptors (TCR) with varying functional avidity. Here the authors show using xenogenic mouse models that antigen reactive TCR-engineered T cells expressing TCRs from a cancer patient with differing functional avidity have differential persistence and function in vivo.

Franziska Füchsl
Johannes Untch
Angela M. Krackhardt
ResearchOpen Access03 Dec 2024
Nature Communications

Volume: 15, P: 1-19
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia

A single-cell screening approach identifies targets for CAR-T cells in acute myeloid leukemia.

Adrian Gottschlich
Moritz Thomas
Sebastian Kobold
Research13 Mar 2023
Nature Biotechnology

Volume: 41, P: 1618-1632
Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation

Synapse loss is prominent in the cortex in multiple sclerosis (MS). In a cortical MS model, Jafari et al. show that phagocytes remove synapses by engulfment, which is triggered by local calcium accumulations and prevented by blocking colony-stimulating factor 1 signaling.

Mehrnoosh Jafari
Adrian-Minh Schumacher
Martin Kerschensteiner
Research25 Jan 2021
Nature Neuroscience

Volume: 24, P: 355-367
A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model

Multiple sclerosis (MS) lesions are initiated by the infiltration of T cells to the CNS. Here, Kendirli et al. use a genome-wide CRISPR screen in an MS model to define the molecules that regulate T cell entry to the CNS.

Arek Kendirli
Clara de la Rosa
Naoto Kawakami
ResearchOpen Access14 Sept 2023
Nature Neuroscience

Volume: 26, P: 1713-1725
CD8⁺ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome

Susac syndrome is an inflammatory pathology of the brain endothelium. Here the authors show that the pathology is driven by CD8 T cells attacking the endothelium, and that blocking T cell-endothelial adhesion ameliorates the disease in a mouse model, and associates with improved clinical score in 4 patients.

Catharina C. Gross
Céline Meyer
Roland Liblau
ResearchOpen Access18 Dec 2019
Nature Communications

Volume: 10, P: 1-19
DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis

Monozygotic (MZ) twins are ideal to study the influence of non-genetic factors on complex phenotypes. Here, Souren et al. perform an EWAS in peripheral blood mononuclear cells from 45 MZ twins discordant for multiple sclerosis and identify disease and treatment-associated epigenetic markers.

Nicole Y. Souren
Lisa A. Gerdes
Jörn Walter
ResearchOpen Access07 May 2019
Nature Communications

Volume: 10, P: 1-12
Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity

Korn and colleagues demonstrate that the site of T cell priming (gut versus skin draining lymph nodes) dictates their effector phenotypes and homing to distal sites of immunopathology.

Michael Hiltensperger
Eduardo Beltrán
Thomas Korn
Research07 Jun 2021
Nature Immunology

Volume: 22, P: 880-892
The impact of genetic diversity on gene essentiality within the Escherichia coli species

A CRISPR interference platform to compare the essentiality of core genes in different genetic backgrounds of Escherichia coli and growth conditions reveals that the essentiality of core genes can substantially vary at the strain level, and can be modulated by HGT and gene loss events.

François Rousset
Jose Cabezas-Caballero
David Bikard
Research18 Jan 2021
Nature Microbiology

Volume: 6, P: 301-312
Amphetamine sensitization alters hippocampal neuronal morphology and memory and learning behaviors

Luis Enrique Arroyo-García
Hiram Tendilla-Beltrán
Gonzalo Flores
Research17 Jun 2020
Molecular Psychiatry

Volume: 26, P: 4784-4794
Development of a crowdsourcing- and gamification-based mobile application to collect epidemiological information and promote healthy lifestyles in Mexico

Kenny Mendoza
Víctor Eduardo Villalobos-Daniel
Simón Barquera
ResearchOpen Access14 Mar 2024
Scientific Reports

Volume: 14, P: 1-12
Niche models at inter- and intraspecific levels reveal hierarchical niche differentiation in midwife toads

Eduardo José Rodríguez-Rodríguez
Juan F. Beltrán
Pedro Aragón
ResearchOpen Access02 Jul 2020
Scientific Reports

Volume: 10, P: 1-11
MiR-23b-3p reduces the proliferation, migration and invasion of cervical cancer cell lines via the reduction of c-Met expression

Gabriela Elizabeth Campos-Viguri
Oscar Peralta-Zaragoza
Gloria Fernández-Tilapa
ResearchOpen Access24 Feb 2020
Scientific Reports

Volume: 10, P: 1-14
Risk factors for developing ventilator-associated lower respiratory tract infection in patients with severe COVID-19: a multinational, multicentre study, prospective, observational study

Luis Felipe Reyes
Alejandro Rodriguez
Neus Guasch
ResearchOpen Access21 Apr 2023
Scientific Reports

Volume: 13, P: 1-15
Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis

Martin Kerick
Marialbert Acosta-Herrera
Javier Martin
ResearchOpen Access05 Oct 2022
npj Genomic Medicine

Volume: 7, P: 1-12
A dataset of acoustic measurements from soundscapes collected worldwide during the COVID-19 pandemic

Samuel Challéat
Nicolas Farrugia
Vera Zina
ResearchOpen Access27 Aug 2024
Scientific Data

Volume: 11, P: 1-16

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Author Correction: IL-17A-secreting γδ T cells promote resistance to CDK4/CDK6 inhibitors in HR⁺HER2⁻ breast cancer via CX3CR1⁺ macrophages

IL-17A-secreting γδ T cells promote resistance to CDK4/CDK6 inhibitors in HR⁺HER2⁻ breast cancer via CX3CR1⁺ macrophages

Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice

Twin study reveals non-heritable immune perturbations in multiple sclerosis

High-resolution profile of neoantigen-specific TCR activation links moderate stimulation to increased resilience of engineered TCR-T cells

Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia

Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation

A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model

CD8⁺ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome

DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis

Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity

The impact of genetic diversity on gene essentiality within the Escherichia coli species

Amphetamine sensitization alters hippocampal neuronal morphology and memory and learning behaviors

Development of a crowdsourcing- and gamification-based mobile application to collect epidemiological information and promote healthy lifestyles in Mexico

Niche models at inter- and intraspecific levels reveal hierarchical niche differentiation in midwife toads

MiR-23b-3p reduces the proliferation, migration and invasion of cervical cancer cell lines via the reduction of c-Met expression

Risk factors for developing ventilator-associated lower respiratory tract infection in patients with severe COVID-19: a multinational, multicentre study, prospective, observational study

Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis

A dataset of acoustic measurements from soundscapes collected worldwide during the COVID-19 pandemic

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