Nature Search

Activation and repression of the 2-5A synthetase and p21 gene promoters by IRF-1 and IRF-2

Eliana M Coccia
Nicoletta Del Russo
Angela Battistini
Research08 Apr 1999
Oncogene

Volume: 18, P: 2129-2137
Author Correction: Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis

Sundararajan Srinivasan
Martina Severa
Cinthia Farina
Amendments and CorrectionsOpen Access11 May 2018
Scientific Reports

Volume: 8, P: 1
Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing

This isoform-centric microglia genomic atlas includes 35,879 novel human microglia isoforms identified by long-read RNA sequencing. A multi-ancestry quantitative trait locus meta-analysis of known and novel isoforms in 555 samples from 391 donors finds associations with genetic risk loci in Alzheimer’s and Parkinson’s diseases.

Jack Humphrey
Erica Brophy
Towfique Raj
Research03 Mar 2025
Nature Genetics

Volume: 57, P: 604-615
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease model

The protein DJ1, encoded by the PARK7 gene, is causally linked to development of early-onset PD. Here the authors observed that the loss of DJ1 function in midbrain organoids led to astrocyte dysfunction, impairing protein clearance, accumulation of α-synuclein.

Gustavo Morrone Parfitt
Elena Coccia
Tim Ahfeldt
ResearchOpen Access10 Jan 2024
Nature Communications

Volume: 15, P: 1-17
Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis

Sundararajan Srinivasan
Martina Severa
Cinthia Farina
ResearchOpen Access21 Aug 2017
Scientific Reports

Volume: 7, P: 1-9
Social and economic variables explain COVID-19 diffusion in European regions

Christian Cancedda
Alessio Cappellato
Stefano Ceri
ResearchOpen Access13 Mar 2024
Scientific Reports

Volume: 14, P: 1-13
Impact of Mycobacterium tuberculosis RD1-locus on human primary dendritic cell immune functions

Marilena P. Etna
Elena Giacomini
Eliana M. Coccia
ResearchOpen Access25 Nov 2015
Scientific Reports

Volume: 5, P: 1-14
SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L

Elena Coccia
Laura Planells-Ferrer
Joan X. Comella
ResearchOpen Access03 Feb 2020
Cell Death & Disease

Volume: 11, P: 1-19
FAIM-L regulation of XIAP degradation modulates Synaptic Long-Term Depression and Axon Degeneration

Ramón Martínez-Mármol
Bruna Barneda-Zahonero
Joan X. Comella
ResearchOpen Access21 Oct 2016
Scientific Reports

Volume: 6, P: 1-16
Role of Ets-1 in transcriptional regulation of transferrin receptor and erythroid differentiation

Giovanna Marziali
Edvige Perrotti
Angela Battistini
Research13 Nov 2002
Oncogene

Volume: 21, P: 7933-7944
Epstein−Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas

Eleni Anastasiadou
Dina Stroopinsky
Frank J Slack
ResearchOpen Access26 Jun 2018
Leukemia

Volume: 33, P: 132-147
Differential regulation of miR-21 and miR-146a by Epstein–Barr virus-encoded EBNA2

P Rosato
E Anastasiadou
P Trivedi
ResearchOpen Access19 Apr 2012
Leukemia

Volume: 26, P: 2343-2352
Loss of tyrosinase activity confers increased skin tumor susceptibility in mice

Anna Saran
Monica Spinola
Tommaso A Dragani
Research08 Mar 2004
Oncogene

Volume: 23, P: 4130-4135

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Activation and repression of the 2-5A synthetase and p21 gene promoters by IRF-1 and IRF-2

Author Correction: Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis

Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing

Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease model

Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis

Social and economic variables explain COVID-19 diffusion in European regions

Impact of Mycobacterium tuberculosis RD1-locus on human primary dendritic cell immune functions

SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L

FAIM-L regulation of XIAP degradation modulates Synaptic Long-Term Depression and Axon Degeneration

Role of Ets-1 in transcriptional regulation of transferrin receptor and erythroid differentiation

Epstein−Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas

Differential regulation of miR-21 and miR-146a by Epstein–Barr virus-encoded EBNA2

Loss of tyrosinase activity confers increased skin tumor susceptibility in mice

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