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Showing 1–50 of 51 results

Advanced filters: Author: Elisabetta Bianchi Clear advanced filters

A designed metal-binding protein with a novel fold

Antonello Pessi
Elisabetta Bianchi
Maurizio Sollazzo
Research25 Mar 1993
Nature

Volume: 362, P: 367-369
Author Correction: NFAT primes the human RORC locus for RORγt expression in CD4+T cells

Hanane Yahia-Cherbal
Magda Rybczynska
Elisabetta Bianchi
Amendments and CorrectionsOpen Access26 Nov 2019
Nature Communications

Volume: 10, P: 1
NFAT primes the human RORC locus for RORγt expression in CD4⁺ T cells

The master transcription factor RORγt, encoded by the RORC gene, controls the polarization of CD4⁺ T cells expressing interleukin-17 (Th17). Here the authors describe several regulatory elements at the RORC locus that are recognized by NFAT and NFkB to induce a permissive epigenetic configuration of the RORC gene for RORγt expression and Th17 differentiation.

Hanane Yahia-Cherbal
Magda Rybczynska
Elisabetta Bianchi
ResearchOpen Access16 Oct 2019
Nature Communications

Volume: 10, P: 1-17
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Research11 Mar 2021
Nature

Volume: 593, P: 136-141
Complex rotational dynamics of the neutron star in Hercules X-1 revealed by X-ray polarization

IXPE has revealed how the spin of the accreting neutron star Hercules X-1 changes in three dimensions. The spin axis of the star moves both through the star and across the sky, hinting that the crust of the star is asymmetric by almost one part in a million.

Jeremy Heyl
Victor Doroshenko
Silvia Zane
Research18 Jun 2024
Nature Astronomy

Volume: 8, P: 1047-1053
Cygnus X-3 revealed as a Galactic ultraluminous X-ray source by IXPE

The accretion geometry of X-ray binary Cygnus X-3 is determined here from IXPE observations. X-ray polarization reveals a narrow funnel with reflecting walls, which focuses emission, making Cyg X-3 appear as an ultraluminous X-ray source.

Alexandra Veledina
Fabio Muleri
Silvia Zane
Research21 Jun 2024
Nature Astronomy

Volume: 8, P: 1031-1046
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity

Elisabetta Bianchi
Simona Denti
Ruggero Pardi
Research06 Apr 2000
Nature

Volume: 404, P: 617-621
Transcript imaging of the development of human T helper cells using oligonucleotide arrays

Lars Rogge
Elisabetta Bianchi
Ulrich Certa
Research01 May 2000
Nature Genetics

Volume: 25, P: 96-101
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis

Michael Seldin and colleagues report a genome-wide association study and meta-analyses for primary biliary cirrhosis. They identify three loci newly associated with susceptibility to this autoimmune liver disease.

Xiangdong Liu
Pietro Invernizzi
Michael F Seldin
Research18 Jul 2010
Nature Genetics

Volume: 42, P: 658-660
Circulating tumor DNA to guide rechallenge with panitumumab in metastatic colorectal cancer: the phase 2 CHRONOS trial

In a phase 2 trial, monitoring tumor resistance mutations in blood using liquid biopsies allowed rationally guided subsequent therapy with anti-EGFR antibodies in patients with colorectal cancer.

Andrea Sartore-Bianchi
Filippo Pietrantonio
Alberto Bardelli
ResearchOpen Access01 Aug 2022
Nature Medicine

Volume: 28, P: 1612-1618
X-ray polarization evidence for a 200-year-old flare of Sgr A^*

A study reports the measurement of the polarization degree and angle of X-rays from Sagittarius A^* reflected off a nearby cloud, indicating an X-ray flare about 200 years ago.

Frédéric Marin
Eugene Churazov
Silvia Zane
Research21 Jun 2023
Nature

Volume: 619, P: 41-45
Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

The monoclonal antibody S309, identified from memory B cells of an individual infected with SARS-CoV in 2003, or antibody cocktails that contain this antibody potently neutralize SARS-CoV-2.

Dora Pinto
Young-Jun Park
Davide Corti
Research18 May 2020
Nature

Volume: 583, P: 290-295
CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-α production in systemic sclerosis

CXCL4 is an inflammatory chemokine signaling through CXCR3 receptor. Here the authors show a CXCR3-independent function of CXCL4: it forms liquid crystals with DNA, potentiating mammalian and bacterial DNA recognition by TLR9, thereby amplifying interferon-a production in systemic sclerosis.

Roberto Lande
Ernest Y. Lee
Loredana Frasca
ResearchOpen Access01 May 2019
Nature Communications

Volume: 10, P: 1-14
Determination of X-ray pulsar geometry with IXPE polarimetry

X-ray polarimetry observations with the Imaging X-ray Polarimetry Explorer constrain the accretion geometry in an X-ray pulsar and provide evidence for a misalignment of the spin, magnetic and orbital axes in Her X-1.

Victor Doroshenko
Juri Poutanen
Fei Xie
Research24 Oct 2022
Nature Astronomy

Volume: 6, P: 1433-1443
Simultaneous space and phase resolved X-ray polarimetry of the Crab pulsar and nebula

X-ray polarization measurements of the Crab nebula and pulsar by the IXPE satellite reveal a global toroidal magnetic field with large variations in local polarization, suggesting a more complex turbulence distribution than anticipated.

Niccolò Bucciantini
Riccardo Ferrazzoli
Silvia Zane
Research06 Apr 2023
Nature Astronomy

Volume: 7, P: 602-610
Vela pulsar wind nebula X-rays are polarized to near the synchrotron limit

Polarization can exceed 60% at the leading edge of the inner part of the Vela pulsar wind nebula; in contrast with the case of the supernova remnant, the electrons in the pulsar wind nebula are accelerated with little or no turbulence in a highly uniform magnetic field.

Fei Xie
Alessandro Di Marco
Silvia Zane
Research21 Dec 2022
Nature

Volume: 612, P: 658-660
Polarized blazar X-rays imply particle acceleration in shocks

Polarization measurements are reported for the blazar Mk501, revealing a degree of X-ray polarization that is more than twice the optical value and supporting the shock-accelerated energy-stratified electron population scenario.

Ioannis Liodakis
Alan P. Marscher
Silvia Zane
ResearchOpen Access23 Nov 2022
Nature

Volume: 611, P: 677-681
Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies

C-type lectins and SIGLEC1 function as attachment receptors for SARS-CoV-2 and enhance ACE2-mediated infection.

Florian A. Lempp
Leah B. Soriaga
Davide Corti
Research31 Aug 2021
Nature

Volume: 598, P: 342-347
Validation of a patient-specific system for mandible-first bimaxillary surgery: ramus and implant positioning precision assessment and guide design comparison

Giovanni Badiali
Mirko Bevini
Claudio Marchetti
ResearchOpen Access07 Aug 2020
Scientific Reports

Volume: 10, P: 1-11
Association between hospitalization-related outcomes, dynapenia and body mass index: The Glisten Study

Andrea P Rossi
Francesco Fantin
Giuseppina dell’Aquila
Research05 Jun 2018
European Journal of Clinical Nutrition

Volume: 73, P: 743-750
Discovery of X-ray polarization angle rotation in the jet from blazar Mrk 421

In June 2022, the IXPE satellite observed a shock passing through the jet of active galaxy Markarian 421. The rotation of the X-ray-polarized radiation over a 5-day period revealed that the jet contains a helical magnetic field.

Laura Di Gesu
Herman L. Marshall
Silvia Zane
Research17 Jul 2023
Nature Astronomy

Volume: 7, P: 1245-1258
Structural basis for HIV-1 neutralization by a gp41 fusion intermediate–directed antibody

Micah A Luftig
Marco Mattu
Andrea Carfí
Research23 Jul 2006
Nature Structural & Molecular Biology

Volume: 13, P: 740-747
Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp

Factor H binding protein (fHbp) is a meningococcal virulence factor and a component of vaccines against serogroup B Neisseria meningitidis. Here, the authors characterize the vaccine-elicited human antibody Fab 1A12 and present both the free and the fHbp-bound Fab 1A12 crystal structures.

Jacinto López-Sagaseta
Peter T. Beernink
Matthew J. Bottomley
ResearchOpen Access06 Feb 2018
Nature Communications

Volume: 9, P: 1-12
Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae

Therapeutics to combat multidrug-resistant bacteria such as Klebsiella pneumoniae are needed. Here the authors show immune evasion drives lipopolysaccharide O2 serotype expansion in multidrug-resistant isolates, and anti-O-antigen human monoclonal antibodies synergize with antibiotics to protect mice from infection.

Meghan E. Pennini
Anna De Marco
C. Kendall Stover
ResearchOpen Access08 Dec 2017
Nature Communications

Volume: 8, P: 1-12
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Use of Sequential Multiple Assignment Randomized Trials (SMARTs) in oncology: systematic review of published studies

Giulia Lorenzoni
Elisabetta Petracci
Oriana Nanni
Reviews26 Dec 2022
British Journal of Cancer

Volume: 128, P: 1177-1188
A genome-wide association study for survival from a multi-centre European study identified variants associated with COVID-19 risk of death

Francesca Minnai
Filippo Biscarini
Francesca Colombo
ResearchOpen Access06 Feb 2024
Scientific Reports

Volume: 14, P: 1-14
A first update on mapping the human genetic architecture of COVID-19

Gita A. Pathak
Juha Karjalainen
J. Kenneth Baillie
ResearchOpen Access03 Aug 2022
Nature

Volume: 608, P: E1-E10
Ablation of soft tissue tumours by long needle variable electrode-geometry electrochemotherapy: final report from a single-arm, single-centre phase-2 study

Andrea Simioni
Sara Valpione
Luca Giovanni Campana
ResearchOpen Access10 Feb 2020
Scientific Reports

Volume: 10, P: 1-13
Multicentre case-control study on the association between COVID-19 vaccines and neurological disorders (COVIVAX)

Elisabetta Pupillo
Elisa Bianchi
Simone Beretta
ResearchOpen Access04 Feb 2025
Scientific Reports

Volume: 15, P: 1-9
Characterization of a new potent and long-lasting single chain peptide agonist of RXFP1 in cells and in vivo translational models

Stephane Illiano
Bruno Poirier
Philip Janiak
ResearchOpen Access28 Nov 2022
Scientific Reports

Volume: 12, P: 1-17
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E24
In vitro models of the crosstalk between multiple myeloma and stromal cells recapitulate the mild NF-κB activation observed in vivo

Federica Colombo
Virginia Guzzeloni
Alessandra Agresti
ResearchOpen Access06 Oct 2024
Cell Death & Disease

Volume: 15, P: 1-18
IgM-secreting diffuse large B-cell lymphoma: results of a multicentre clinicopathological and molecular study

M. Christina Cox
Luigi Marcheselli
Arianna Di Napoli
Research20 Sept 2022
Leukemia

Volume: 36, P: 2719-2723
Survivability of the lichen Xanthoria parietina in simulated Martian environmental conditions

Christian Lorenz
Elisabetta Bianchi
Mickaël Baqué
ResearchOpen Access25 Mar 2023
Scientific Reports

Volume: 13, P: 1-15
How a faecal immunochemical test screening programme changes annual colorectal cancer incidence rates: an Italian intention-to-screen study

Lauro Bucchi
Silvia Mancini
Daniele Trombetti
ResearchOpen Access20 Apr 2022
British Journal of Cancer

Volume: 127, P: 541-548
Polypharmacy through Phage Display: Selection of Glucagon and GLP-1 Receptor Co-agonists from a Phage-Displayed Peptide Library

Anna Demartis
Armin Lahm
Antonello Pessi
ResearchOpen Access12 Jan 2018
Scientific Reports

Volume: 8, P: 1-9
Human remains from Arma di Nasino (Liguria) provide novel insights into the paleoecology of early Holocene foragers in northwestern Italy

Vitale S. Sparacello
Gwenaëlle Goude
Elisabetta Starnini
ResearchOpen Access29 Sept 2023
Scientific Reports

Volume: 13, P: 1-14
An explainable model of host genetic interactions linked to COVID-19 severity

A multifaceted computational strategy identifies 16 genetic variants contributing to increased risk of severe COVID-19 infection from a Whole Exome Sequencing dataset of a cohort of Italian patients.

Anthony Onoja
Nicola Picchiotti
Francesco Raimondi
ResearchOpen Access26 Oct 2022
Communications Biology

Volume: 5, P: 1-14
Health-related quality of life of newly diagnosed chronic myeloid leukemia patients treated with first-line dasatinib versus imatinib therapy

Fabio Efficace
Fabio Stagno
Gianantonio Rosti
Research02 Sept 2019
Leukemia

Volume: 34, P: 488-498
Impact of SARS-CoV-2 vaccination and passive prophylaxis with tixagevimab/cilgavimab on CAR-T patients: a three-year regional experience from the Italian covid pandemic

Eugenio Galli
Alice Di Rocco
Federica Sorà
Correspondence04 Sept 2023
Bone Marrow Transplantation

Volume: 58, P: 1394-1396
Infections by carbapenem-resistant Klebsiella pneumoniae in SCT recipients: a nationwide retrospective survey from Italy

C Girmenia
G M Rossolini
Giuseppe Milone
Research13 Oct 2014
Bone Marrow Transplantation

Volume: 50, P: 282-288
Pathway-based analysis of primary biliary cirrhosis genome-wide association studies

S P Kar
M F Seldin
C I Amos
Research07 Feb 2013
Genes & Immunity

Volume: 14, P: 179-186
Chronic myeloid leukemia management at the time of the COVID-19 pandemic in Italy. A campus CML survey

Massimo Breccia
Elisabetta Abruzzese
Levato Luciano
Correspondence18 Jun 2020
Leukemia

Volume: 34, P: 2260-2261
Rare variants in Toll-like receptor 7 results in functional impairment and downregulation of cytokine-mediated signaling in COVID-19 patients

Stefania Mantovani
Sergio Daga
Alessandra Renieri
ResearchOpen Access24 Dec 2021
Genes & Immunity

Volume: 23, P: 51-56
Changes in Stem Cell Transplant activity and procedures during SARS-CoV2 pandemic in Italy: an Italian Bone Marrow Transplant Group (GITMO) nationwide analysis (TransCOVID-19 Survey)

Domenico Russo
Nicola Polverelli
Francesca Elice
Correspondence19 Apr 2021
Bone Marrow Transplantation

Volume: 56, P: 2272-2275
Ruxolitinib discontinuation syndrome: incidence, risk factors, and management in 251 patients with myelofibrosis

Francesca Palandri
Giuseppe Alberto Palumbo
Massimiliano Bonifacio
CorrespondenceOpen Access07 Jan 2021
Blood Cancer Journal

Volume: 11, P: 1-4
The IL-23/IL-17 pathway in human chronic inflammatory diseases—new insight from genetics and targeted therapies

Elisabetta Bianchi
Lars Rogge
Reviews19 Apr 2019
Genes & Immunity

Volume: 20, P: 415-425

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