Type 2 taste receptors (Tas2rs in mice and TAS2Rs in humans) detect bitter stimuli and are present in both the oral cavity and extraoral sites. In this Review, the authors discuss Tas2rs/TAS2Rs in the gastrointestinal enteroendocrine system and how they could be potential targets to prevent or treat metabolic disorders.
- Catia Sternini
- Enrique Rozengurt