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Showing 1–50 of 145 results

Advanced filters: Author: F van Rhee Clear advanced filters

National identity predicts public health support during a global pandemic

Understanding collective behaviour is an important aspect of managing the pandemic response. Here the authors show in a large global study that participants that reported identifying more strongly with their nation reported greater engagement in public health behaviours and support for public health policies in the context of the pandemic.

Jay J. Van Bavel
Aleksandra Cichocka
Paulo S. Boggio
ResearchOpen Access26 Jan 2022
Nature Communications

Volume: 13, P: 1-14
Long-term results after allogeneic bone marrow transplantation for chronic myelogenous leukemia in chronic phase: a report from the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation

F van Rhee
RM Szydlo
A Gratwohl
Research01 Oct 1997
Bone Marrow Transplantation

Volume: 20, P: 553-560
Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study

Global Burden of Disease estimates show that between 1990 and 2023, the prevalence and burden of drug use disorders, inclusive of amphetamine, cannabis, cocaine and opioid use, have been increasing in high-income countries, particularly in the USA.

Jiseung Kang
Hyeon Jin Kim
Dong Keon Yon
Research16 Jan 2026
Nature Medicine

Volume: 32, P: 527-544
Adoptive immunotherapy for relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: equal efficacy of lymphocytes from sibling and matched unrelated donors

F van Rhee
D Savage
JM Goldman
Research14 May 1998
Bone Marrow Transplantation

Volume: 21, P: 1055-1061
The Hubble constant from VLA measurement of the time delay in the double quasar 0957+561

David H Roberts
Joseph Lehár
Bernard F Burke
Research04 Jul 1991
Nature

Volume: 352, P: 43-45
Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

B. Margolis
P. Hu
J. Schlessinger
Research05 Mar 1992
Nature

Volume: 356, P: 71-74
Polygenic prediction of body mass index and obesity through the life course and across ancestries

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

Roelof A. J. Smit
Kaitlin H. Wade
Ruth J. F. Loos
ResearchOpen Access21 Jul 2025
Nature Medicine

Volume: 31, P: 3151-3168
Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function

Pathogenic variants in UNC13A underlie a novel neurodevelopmental syndrome, with three subtypes defined by distinct genotypes with varying clinical and functional impacts characterized in cellular and animal models.

Reza Asadollahi
Aisha Ahmad
Noa Lipstein
ResearchOpen Access22 Oct 2025
Nature Genetics

Volume: 57, P: 2691-2704
PSMA PET–CT in initial prostate cancer staging

The speed with which PSMA PET–CT has been adopted for prostate cancer imaging is unprecedented. This technique's clinical value in recurrent disease is uncontested, but its role in initial staging is unclear. Two studies now provide important data on the value of PSMA PET–CT at this management stage.

Frederik A. Verburg
Andreas Pfestroff
News & Views19 Jul 2016
Nature Reviews Urology

Volume: 13, P: 498-499
A saturated map of common genetic variants associated with human height

A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

Loïc Yengo
Sailaja Vedantam
Joel N. Hirschhorn
ResearchOpen Access12 Oct 2022
Nature

Volume: 610, P: 704-712
The power of genetic diversity in genome-wide association studies of lipids

A genome-wide association meta-analysis study of blood lipid levels in roughly 1.6 million individuals demonstrates the gain of power attained when diverse ancestries are included to improve fine-mapping and polygenic score generation, with gains in locus discovery related to sample size.

Sarah E. Graham
Shoa L. Clarke
Cristen J. Willer
Research09 Dec 2021
Nature

Volume: 600, P: 675-679
Evolution of the mammalian G protein α subunit multigene family

Thomas M. Wilkie
Debra J. Gilbert
Neal G. Copeland
Research01 May 1992
Nature Genetics

Volume: 1, P: 85-91
Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

Blood metabolite levels are under the influence of environmental and genetic factors. Here, Hagenbeek et al. perform heritability estimations for metabolite measures and determine the contribution of known metabolite loci to metabolite levels using data from 40 genome-wide association studies.

Fiona A. Hagenbeek
René Pool
Dorret I. Boomsma
ResearchOpen Access07 Jan 2020
Nature Communications

Volume: 11, P: 1-11
Sequence and functional expression of the GABA_A receptor shows a ligand-gated receptor super-family

Peter R. Schofield
Mark G. Darlison
Eric A. Barnard
Research16 Jul 1987
Nature

Volume: 328, P: 221-227
Orbital evolution of low-mass X-ray binaries due to radiation driven mass transfer

Marco Tavani
Research02 May 1991
Nature

Volume: 351, P: 39-41
pH distributions in spontaneous and isotransplanted rat tumours

F Kallinowski
P Vaupel
Research01 Sept 1988
British Journal of Cancer

Volume: 58, P: 314-321
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease

JJM van Dongen
EA Macintyre
A Biondi
Research02 Dec 1999
Leukemia

Volume: 13, P: 1901-1928
Structural and functional basis for GABA_A receptor heterogeneity

Edwin S. Levitan
Peter R. Schofield
Peter H. Seeburg
Research01 Sept 1988
Nature

Volume: 335, P: 76-79
Gene expression profiles of human endometrial cancer samples using a cDNA-expression array technique: assessment of an analysis method

E Smid-Koopman
L J Blok
F J Huikeshoven
ResearchOpen Access20 Jun 2000
British Journal of Cancer

Volume: 83, P: 246-251
Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets

Jae-We Cho
Kun Park
Seong-Il Suh
ResearchOpen Access01 Jun 2005
Experimental & Molecular Medicine

Volume: 37, P: 186-192
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

Barbara L. Hempstead
Dionisio Martin-Zanca
Moses V. Chao
Research25 Apr 1991
Nature

Volume: 350, P: 678-683
Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial

In this phase 1 trial, patients with locally advanced or metastatic solid tumors were treated with the individualized mRNA neoantigen-specific immunotherapy (iNeST) autogene cevumeran alone or in combination with the anti-PD-L1 agent atezolizumab, showing long-lasting neoantigen-specific immune responses and preliminary clinical activity, supporting further development of this therapeutic approach.

Juanita Lopez
Thomas Powles
D. Ross Camidge
ResearchOpen Access06 Jan 2025
Nature Medicine

Volume: 31, P: 152-164
Time-resolved Brownian tomography of single nanocrystals in liquid during oxidative etching

Atomic structural changes in nanocrystals are still poorly understood. Here, the authors introduce time-resolved Brownian tomography to directly detect 3D atomic changes in Pt nanocrystals during oxidative etching and reveal disorder at sizes of ≈1 nm.

Sungsu Kang
Joodeok Kim
Jungwon Park
ResearchOpen Access29 Jan 2025
Nature Communications

Volume: 16, P: 1-13
Specific binding of antigenic peptides to cell-associated MHC class I molecules

Immanuel F. Luescher
Pedro Romero
Janet L. Maryanski
Research02 May 1991
Nature

Volume: 351, P: 72-74
Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

Genome-wide association meta-analysis of AAA identifies 121 independent risk loci and highlights potential therapeutic targets such as proprotein convertase, subtilisin/kexin-type 9 (PCSK9).

Tanmoy Roychowdhury
Derek Klarin
Scott M. Damrauer
ResearchOpen Access16 Oct 2023
Nature Genetics

Volume: 55, P: 1831-1842
Purging in BCR-ABL-positive acute lymphoblastic leukemia using immunomagnetic beads: comparison of residual leukemia and purging efficiency in bone marrow vs peripheral blood stem cells by semiquantitative polymerase chain reaction

J Atta
F Fauth
H Martin
Research25 Jan 2000
Bone Marrow Transplantation

Volume: 25, P: 97-104
Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

Genetic variants at multiple loci of chr5p15.33 have been associated with susceptibility to numerous cancers. Here the authors show that the association of one of these loci may be explained by a variant, rs36115365, influencing telomerase reverse transcriptase (TERT) expression via ZNF148.

Jun Fang
Jinping Jia
Laufey T. Amundadottir
ResearchOpen Access27 Apr 2017
Nature Communications

Volume: 8, P: 1-17
Second allogeneic bone marrow transplantation in acute leukemia: a multicenter study from the Gruppo Italiano Trapianto Di Midollo Osseo (GITMO)

A Bosi
S Bacci
A Amici
Research01 Mar 1997
Leukemia

Volume: 11, P: 420-424
Good correlation between RT-PCR analysis and relapse in Philadelphia (Ph1)-positive acute lymphoblastic leukemia (ALL)

C Preudhomme
N Henic
P Fenaux
Research01 Feb 1997
Leukemia

Volume: 11, P: 294-298
Detection and quantitation of the CBFβ/MYH11 transcripts associated with the inv(16) in presentation and follow-up samples from patients with AML

PAS Evans
MA Short
GJ Morgan
Research01 Mar 1997
Leukemia

Volume: 11, P: 364-369
Is double autologous stem-cell transplantation appropriate for new multiple myeloma patients?

Frits van Rhee
Comments & Opinion06 Nov 2007
Nature Clinical Practice Oncology

Volume: 5, P: 70-71
Deciphering the genetics and mechanisms of predisposition to multiple myeloma

Multiple myeloma (MM) is an incurable blood malignancy. Here, the authors report 35 MM risk loci and two causal mechanisms for genetic MM risk: longer telomeres and elevated plasma B-cell maturation antigen (BCMA) and interleukin−5 receptor alpha (IL5RA) levels.

Molly Went
Laura Duran-Lozano
Björn Nilsson
ResearchOpen Access05 Aug 2024
Nature Communications

Volume: 15, P: 1-15
Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level

The spatial architecture of multiple myeloma remains to be explored. Here, the authors perform bulk and single cell sequencing for samples from newly diagnosed patients and reveal gene signatures associated with focal lesions and spatial heterogeneity in the tumour microenvironment.

Lukas John
Alexandra M. Poos
Niels Weinhold
ResearchOpen Access17 Aug 2023
Nature Communications

Volume: 14, P: 1-17
Functional dissection of inherited non-coding variation influencing multiple myeloma risk

The causality and functional roles of disease-associated variants revealed by genome-wide association studies (GWAS) are mostly unexplored. Here the authors identify putative causal variants in multiple myeloma and find their association with gene expression and chromatin accessibility.

Ram Ajore
Abhishek Niroula
Björn Nilsson
ResearchOpen Access10 Jan 2022
Nature Communications

Volume: 13, P: 1-15
Author Correction: The power of genetic diversity in genome-wide association studies of lipids

Sarah E. Graham
Shoa L. Clarke
Cristen J. Willer
Amendments and Corrections26 May 2023
Nature

Volume: 618, P: E19-E20
Extramedullary relapse after favorable molecular response to donor leukocyte infusions for recurring acute leukemia

C Berthou
MC Léglise
J-F Abgrall
Research22 Oct 1998
Leukemia

Volume: 12, P: 1676-1681
Accelerated single cell seeding in relapsed multiple myeloma

In multiple myeloma, disease progresses via seeding to different anatomic sites and clonal expansion. Here, utilising autopsy material, the authors show that systemic seeding accelerates at relapse following treatment.

Heather J. Landau
Venkata Yellapantula
Francesco Maura
ResearchOpen Access17 Jul 2020
Nature Communications

Volume: 11, P: 1-10
Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-γ1-driven activation of mTOR/p70S6-kinase pathway

B Markova
C Albers
T Fischer
Research02 Nov 2009
Oncogene

Volume: 29, P: 739-751
High incidence of adeno- and polyomavirus-induced hemorrhagic cystitis in bone marrow allotransplantation for hematological malignancy following T cell depletion and cyclosporine

R Childs
C Sanchez
AJ Barrett
Research30 Oct 1998
Bone Marrow Transplantation

Volume: 22, P: 889-893
International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders

A Dispenzieri
R Kyle
B G M Durie
Reviews20 Nov 2008
Leukemia

Volume: 23, P: 215-224
Interferon alpha for chronic myeloid leukemia relapsing after allogeneic bone marrow transplantation

J L Steegmann
L F Casado
J M Fernández-Rañada
Research26 Feb 1999
Bone Marrow Transplantation

Volume: 23, P: 483-488
Multiplex PCR for quality control of template RNA/cDNA in RT-PCR assays

F Watzinger
T Lion
Research08 Dec 1998
Leukemia

Volume: 12, P: 1983-1993
HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype

Genome-wide analyses identify variants near HDAC9 associated with abdominal aortic calcification and other cardiovascular phenotypes. Functional work shows that HDAC9 promotes an osteogenic vascular smooth muscle cell phenotype, enhancing calcification and reducing contractility.

Rajeev Malhotra
Andreas C. Mauer
Christopher J. O’Donnell
Research28 Oct 2019
Nature Genetics

Volume: 51, P: 1580-1587
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

Primary open-angle glaucoma (POAG) is highly heritable, yet not well understood from a genetic perspective. Here, the authors perform a meta-analysis of genome-wide association studies in 34,179 POAG cases, identifying 44 previously unreported risk loci and mapping effects across multiple ethnicities.

Puya Gharahkhani
Eric Jorgenson
Janey L. Wiggs
ResearchOpen Access24 Feb 2021
Nature Communications

Volume: 12, P: 1-16
Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

In multiple myeloma, malignant cells expand within bone marrow. Here, the authors use multi-region sequencing in patient samples to analyse spatial clonal architecture and heterogeneity, providing novel insight into multiple myeloma progression and evolution.

L. Rasche
S. S. Chavan
N. Weinhold
ResearchOpen Access16 Aug 2017
Nature Communications

Volume: 8, P: 1-11
Inositol phosphates and cell signalling

Michael J. Berridge
Robin F. Irvine
Reviews21 Sept 1989
Nature

Volume: 341, P: 197-205
The crystal structure of the antifungal protein zeamatin, a member of the thaumatin-like, PR-5 protein family

The crystal structure of zeamatin, and comparisons within the family, suggest most PR-5 proteins have an electrostatically polarized surface which may be responsible for antifungal activity.

Michael A. Batalia
Arthur F. Monzingo
Jon D. Robertus
Correspondence01 Jan 1996
Nature Structural Biology

Volume: 3, P: 19-22
Chemical Regulation of Bacillus Thuringiensis ∂-Endotoxin Expression in Transgenic Plants

Shericca Williams
Leslie Friedrich
John Rylas
Research01 May 1992
Bio/Technology

Volume: 10, P: 540-543
The sunflower genome provides insights into oil metabolism, flowering and Asterid evolution

A high-quality reference for the sunflower genome (Helianthus annuus L.) and analysis of gene networks involved in flowering time and oil metabolism provide a basis for nutritional exploitation and analyses of adaptation to climate change.

Hélène Badouin
Jérôme Gouzy
Nicolas B. Langlade
ResearchOpen Access22 May 2017
Nature

Volume: 546, P: 148-152
A comparison of prophylactic vs pre-emptive ganciclovir to prevent cytomegalovirus disease after T-depleted volunteer unrelated donor bone marrow transplantation

R Stocchi
R Szydlo
K N Ward
Research23 Mar 1999
Bone Marrow Transplantation

Volume: 23, P: 705-709

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