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Two-qubit operations exceeding 99% fidelity have been demonstrated by silicon devices made with standard semiconductor tooling in a 300-mm foundry environment.

Hole spin qubits in germanium have seen significant advancements, though improving control and noise resilience remains a key challenge. Here, the authors realize a dressed singlet-triplet qubit in germanium, achieving frequency-modulated high-fidelity control and a tenfold increase in coherence time.

Silicon carbide is a polymorphic material with over 250 known crystal structures. Here the authors show that such polymorphism can be used as a degree of freedom for engineering optically addressable and coherently interacting spin states, including many with room-temperature quantum coherence.

Epitaxial quantum dots in group III-V semiconductors are promising candidates for qubits and quantum memories, but nuclear spin coherence has been limited to 1 ms range. Here the authors achieve coherence times exceeding 100 ms in GaAs quantum dots using strain engineering and dynamical decoupling.

Introgression of the short arm of rye chromosome one into common wheat increases root biomass and drought tolerance, but the underlying genetic basis is unknown. Here, the authors report that dosage differences in 12-OXOPHYTODIENOATE REDUCTASE genes modulate the differences of wheat root architecture.

Current applications of NV centers in diamond as spin-photon interfaces for quantum networks are limited by low coherent photon emission. Here, the authors integrate a coherently controlled NV spin qubit with an open microcavity to achieve Purcell-enhanced emission and demonstrate spin-photon state generation.

Trapped ions are promising for electrometry but limited by their weak intrinsic spin coupling to electric fields. Now it is shown that using a magnetic field gradient enhances sensitivity and enables precise measurements across subhertz to kilohertz frequencies.

The authors report the sweet-spot operation of germanium hole spin qubits, exploring the optimization of the external magnetic field orientation, the g-tensor and its electric tunability, and hyperfine interactions.

A three-dimensional (3D) nanofabrication platform based on metalens-generated focal spot arrays is introduced to parallelize two-photon lithography beyond centimetre-scale write field areas, revealing the potential of 3D nanolithography towards wafer-scale production.

Silicon is a promising material for realization of quantum processors, particularly as it could be naturally integrated with classical control hardware based on CMOS technology. Here the authors report a silicon qubit device made with an industry-standard fabrication process on a CMOS platform.

Juvenile idiopathic arthritis (JIA) associated uveitis can cause vision loss in children, but mechanisms remain unclear. The authors here identify elevated CD19⁺IgD^-CD27^- double negative type 1 B cells in JIA-uveitis and show that targeting B-T cell interactions suppresses disease in mouse models of uveitis.

Recently released documents give the inside story of Otto Hahn's 1944 Nobel prize in chemistry for the discovery of nuclear fission. They reveal flaws in the award-making process — and an attempt to rewrite history.

Plant traits drive ecosystem dynamics yet are challenging to map globally due to sparse measurements. Here, the authors combine crowdsourced biodiversity observations with Earth observation data to accurately map 31 plant traits at 1 km² resolution.

Identifying jets originating from heavy quarks plays a fundamental role in hadronic collider experiments. In this work, the ATLAS Collaboration describes and tests a transformer-based neural network architecture for jet flavour tagging based on low-level input and physics-inspired constraints.

KLHL23 and RhoGDI compete for CDC42’s switch II region in a GTP- or GDP-dependent manner, driving spatiotemporal inactivation through degradation or sequestration. This dynamic control maintains membrane homeostasis and is impaired in Takenouchi–Kosaki Syndrome.

A scalable silicon quantum processor unit cell made of two qubits confined to quantum dots operates at about 1.5 K, achieving 98.6% single-qubit gate fidelities and a 2 μs coherence time.

Despite recent advances in targeting RAS, resistance to anti-RAS therapies limits their effectiveness in KRAS-mutant lung cancer. Here, the authors show that RAS inhibitors impair wild-type KRAS degradation, leading to its accumulation and resistance through mTOR, and demonstrate that targeting mTOR or amino acid transport can overcome this resistance.

In targeted protein degradation, a degrader molecule brings a neosubstrate protein proximal to a hijacked E3 ligase for its ubiquitination. Here, pseudo-natural products derived from (−)-myrtanol—iDegs—are identified to inhibit and induce degradation of the immunomodulatory enzyme indoleamine-2,3-dioxygenase 1 (IDO1) by a distinct mechanism. iDegs prime apo-IDO1 ubiquitination and subsequent degradation using its native proteolytic pathway.

This work challenges the view of nucleation governing halide perovskite grain morphology, showing that most additives act post-nucleation by boosting ion mobility across grain boundaries, triggering grain coarsening, similar to post-processing effects.

The trade-off between long lifetime and inevitable radiative decay to a control line has become a key limitation for superconducting qubits. Here, the authors break the trade-off by coupling another qubit to the control line of the first one to suppress its relaxation, while enabling fast qubit control.

Fractal analysis of structural MRI captures the formation of brain shape in human newborns and outperforms other morphological measures in predicting infant age and genetic similarity, including the identification of twins from their brain data.

Detecting the magnetic spins of a small number of atoms is important for applications such as magnetic resonance imaging. Here, Steinert et al.demonstrate that nitrogen-vacancy defect centres in diamond allow spin detection at room temperature at length scales smaller than human cells.

Solid-state systems are established candidates to study models of many-body physics but have limited control and readout capabilities. Ensembles of defects in diamond may provide a solution for studying dipolar systems.

The CMS Collaboration reports the measurement of the spin, parity, and charge conjugation properties of all-charm tetraquarks, exotic fleeting particles formed in proton–proton collisions at the Large Hadron Collider.

Carbon nanotubes are promising hosts for spin qubits, however existing demonstrations show limited coherence times. Here the authors report quantum states in a carbon-nanotube-based circuit driven solely by cavity photons and exhibiting a coherence time of about 1.3 μs.

Superconducting transmon qubits have been fabricated in a 300 mm complementary metal–oxide–semiconductor (CMOS) pilot line using industrial fabrication methods, achieving relaxation and coherence times exceeding 100 μs.

Point defects in diamond known as nitrogen-vacancy centres have been shown to be sensitive to minute magnetic fields, even at room temperature. A demonstration that the spin associated with these defect centres is also sensitive to electric fields holds out the prospect of a sensor that can resolve, under ambient conditions, single spins and single elementary charges at the nanoscale.

Microglial states throughout remyelination are incompletely understood. Here, the authors show that microglia form several states during the early stages of remyelination that coalesce into a partially resolved state that is dysregulated with age.

Ion implantation is used to introduce spin defects in solids, but it inflicts residual lattice damage, degrading performances. Here the authors demonstrate that the charge state of induced defects influences such damage, and that charging vacancies leads to improved coherence times and yield of centres.

Deciphering the formation sequence of surface methoxy species (SMS) and dimethyl ether (DME) in zeolite-catalyzed methanol reactions remains a challenge. Here, the authors tackle this issue by employing a microenvironment design strategy to steer reaction pathways within zeolite channels, enabling SMS formation from DME decomposition catalyzed by Brønsted acids at 363 K.

The electron spin in a silicon-based quantum dot can be controlled electrically for as long as several tens of microseconds, which improves the prospects for quantum information processing based on this type of quantum dot.

Although electrometers based on quantum defects have advanced, achieving time-resolved detection of charges with subnanometer resolution remains challenging. Here the authors use a negatively charged tin-vacancy center in diamond to distinguish charge traps at the lattice scale with high temporal precision.

In this Review, Grapsa and colleagues provide an overview of the imaging modalities used in the diagnosis and management of tricuspid regurgitation, describe the valve repair and replacement strategies undergoing clinical testing, and highlight the technological innovations that aim to optimize diagnosis, patient selection and the device development process.

Colour centres are a promising quantum information platform, but coherence degradation after integration in nanostructures has hindered scalability. Here, the authors show that waveguide-integrated V_Si centres in SiC maintain spin-optical coherences, enabling nuclear high-fidelity spin qubit operations.

Ethanol-induced fructose metabolism, mediated by KHK-A/C, drives excessive alcohol consumption and pathogenesis of alcoholic liver disease.