For asymmetric catalysis, chiral cobalt catalysts have garnered considerable attention, but there remains an absence of reactive chiral cobalt catalysts constructed exclusively from achiral ligands. Herein, the authors report a reactive chiral-at-cobalt catalyst comprised entirely of achiral ligands, and its application in visible-light-activated enantioselective transformation of isoxazoles into chiral 2H-azirines.
- Su-Yang Yao
- Marco Villa
- Eric Meggers
