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Showing 1–6 of 6 results

Advanced filters: Author: Fangyu Cheng Clear advanced filters

The impact of library size and scale of testing on virtual screening

The docking of a 1.7 billion- versus a 99 million-molecule virtual library against β-lactamase revealed that the larger-sized library produced improved hit rates and potency along with an increased number of scaffolds.

Fangyu Liu
Olivier Mailhot
Brian K. Shoichet
Research03 Jan 2025
Nature Chemical Biology

Volume: 21, P: 1039-1045
circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1

Circular RNAs are known to regulate cancer. Here, the authors show that the circular RNA circTP63 promotes lung squamous cell carcinoma by competing with endogenous RNA to upregulate FOXM1.

Zhuoan Cheng
Chengtao Yu
Wenxin Qin
ResearchOpen Access19 Jul 2019
Nature Communications

Volume: 10, P: 1-13
Space dynamic target tracking method based on five-frame difference and Deepsort

Cheng Huang
Quanli Zeng
Jiazhong Xu
ResearchOpen Access12 Mar 2024
Scientific Reports

Volume: 14, P: 1-19
Association of immunonutritional indicators with all-cause mortality in adult stroke patients

Kai Deng
Shangang Feng
Chunping Wang
ResearchOpen Access28 Apr 2025
Scientific Reports

Volume: 15, P: 1-10
STAT5A modulates CDYL2/SLC7A6 pathway to inhibit the proliferation and invasion of hepatocellular carcinoma by targeting to mTORC1

Xiaoxia Chen
Zhenyu Wang
Jinjun Li
Research21 Mar 2022
Oncogene

Volume: 41, P: 2492-2504
SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs

Qun Chen
Fan Zhang
Chen-Yu Zhang
ResearchOpen Access17 Aug 2020
Cell Research

Volume: 31, P: 247-258