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Lignin refining continues to face major challenges in achieving selective depolymerization and breaking resistant C–C bonds. In this work, the authors design a robust atomically dispersed Cu/Ni-SA@HNC catalyst that enables highly selective hydrogenolysis of lignin and model compounds through an unconventional pathway involving preferential Cα–Cβ bond cleavage in β-O-4 linkages.

Surface-enhanced Raman spectroscopy is widely used for rapid and sensitive molecular detection in chemistry and biology, but typically relies on noble metals. Here the authors report a non-stoichiometric semiconducting material with defect-rich surface that displays excellent detection limits and enhancement factors.

The authors report magnetotransport evidence for the coexistence of a two-dimensional (2D) superconducting state and a 2D ferromagnetic state at the interface between amorphous CaZrO₃ film and KTaO₃ single crystal. Moreover, the magnetoresistance hysteresis reaches a maximum near the superconducting transition temperature.

The performance of macroscopic graphene fibers is hampered by lower bonding strength between individual graphene sheets. Authors mitigate this by creating covalent conjugating linkages at sheet edges, improving mechanical and electrical properties.

Perovskite oxides, when combined into heterostructures and superlattices can yield emergent properties not present in the constituent components. Here, by combining LaNiO3, a Pauli paramagnetic material, with LaFeO3, an antiferromagnetic insulator, Zhou et al create a strongly ferromagnetic superlattice with a Curie temperature of over 600 K.

Neutralizing antibodies are currently one versatile strategy to treat SARS-CoV-2 infection. Here, Li et al. characterize three monoclonal antibodies neutralizing authentic virus infection in vitro and in vivo by targeting the receptor binding domain as evidenced by Cryo-EM.

Thermal switches are critical for preventing overheating and ensuring safety. Here, the authors present a thermomagnetic liquid metal (TMLM) thermal switch with a fast bidirectional response, enhancing speed, functionality, and potential for diverse applications.

Larger orbital polarization is highly desired in the nickelate-based superconductivity. Here, the authors report on the improved conduction and large in-plane polarization up to 35% in ultrathin LaNiO₃ layer with a distinct octahedron rotation.

CRISPR-Cas12e systems exhibit robust genome editing capabilities, yet their phylogenetic diversity remains underexplored. Here, authors elucidate the biochemical diversity and structural variations of newly identified Cas12e proteins, offering critical insights into structure-activity relationships.

Complex oxide heterostructures exhibit multifunctional behaviour that could be used in a range of device applications. Here, the authors observe that reconstruction at oxide perovskite/brownmillerite interfaces leads to perpendicular magnetic spin orientation, with potential use in spintronic devices.

The trade-off between grain number and grain weight is a major obstacle for increasing rice yield. Here, the authors show that variation in 5’ UTR of OsMADS17 can simultaneously increase grain number and grain weight through decreasing mRNA translation efficiency.

The utilization of waste heat is an important way of combining energy saving to emission reductions. Here, authors demonstrate a magnetocaloric material as a controlling switch in a thermomagnetic generator for waste heat recovery.

Fan Zhang et al. present CRISPRminer, a comprehensive database for exploring CRISPR-Cas systems in more than 3500 microbial species and a web-server for in-depth data mining. CRISPRminer allows researchers to predict CRISPR-Cas systems and investigate self-targeting CRISPRs, microbe-phage interaction networks, and anti-CRISPR features.

Capacity is often used to evaluate and monitor battery state and health. Now, lithium inventory transactions can be accurately tracked at the electrode–electrolyte interface to improve battery performance and reliability.

Zhou, Duan, Wang et al. show that d-2-hydroxyglutarate affects mitochondrial health by inhibiting the 3-hydroxypropionate (3-HP) dehydrogenase HPHD-1, leading to a build-up of 3-HP and interference with IMMT-1 (also knowns as MIC60) function in mitochondria structure.

Inflammasome signalling has been shown to protect Candida albicans during infection and as such limits inflammasome inhibitors in this context. Here the authors implicate Gasdermin D in C.ablicans immune evasion and suggests its targeting therapeutically.

Callus browning heavily affects indica rice transformation regeneration. Here, the authors show transposon insertion in the promoter of BOC1 gene, encoding a SIMILAR TO RADICAL-INDUCED CELL DEATH ONE protein, can upregulate its expression and decrease callus browning in cultivated rice by releasing oxidative stress.

Zhiwei Huang and colleagues report structural and biochemical data showing that the anti-CRISPR protein AcrVA5 functions as an acetyltransferase, modifying MbCas12a at Lys635, a residue required for PAM recognition. Acetylation of Lys635 creates a steric clash that prevents binding of target DNA.

Ovarian cancer is common among women and is the leading cause of death from gynaecological malignancies. Here the authors identify two previously unknown genetic variants that increase the risk of epithelial ovarian cancer in Han Chinese women.

Mechanical cleavage of layered materials to obtain two-dimensional (2D) sheets is restricted to materials with interlayer interactions dominated by van der Waals (vdW) forces. Here, calendering is used to weaken interlayer binding in non-vdW layered structures (metals, semiconductors and superconductors) allowing mechanical exfoliation to obtain 2D sheets with thickness-dependent properties.

It is believed that mutations in desmosomal adhesion complex protein plakophilin 2 (PKP2) cause arrhythmia due to loss of cell-cell communication. Here the authors show that PKP2 controls the expression of proteins involved in calcium cycling in adult mouse hearts, and that lack of PKP2 can cause arrhythmia in a structurally normal heart.

Luo and colleagues use single-cell RNA sequencing to provide a comprehensive transcriptional landscape of neutrophil maturation, function and fate decision in their steady state and during bacterial infection.

In this paper, we report the dimensional control of the interface coupling-induced ferromagnetic phase in perovskite-CaRuO₃/infinite-layered-SrCuO₂ superlattices. The Hall and magnetoresistance measurements indicate the appearance of an interfacial ferromagnetic state in the originally paramagnetic CaRuO₃ layers when the CaRuO₃ layer is in proximity to the chain-type SrCuO₂ layers; this superlattice has the highest Curie temperature of ~75 K and perpendicular magnetic anisotropy. Along with the thickness-driven structural transition from chain-type to planar-type of the SrCuO₂ layers, the interfacial ferromagnetic order gradually deteriorates and finally disappears.