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Showing 51–100 of 128 results

Advanced filters: Author: Frédéric Guillaume Clear advanced filters

Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Amendments and CorrectionsOpen Access12 Jan 2022
Nature Medicine

Volume: 28, P: 212
Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Research10 Jan 2022
Nature Medicine

Volume: 28, P: 53-58
rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences

Myotonic dystrophy (DM) type 2 is a neuromuscular pathology caused by large expansions of CCTG repeats. Here the authors find that rbFOX1 RNA binding protein binds to CCUG RNA repeats and competes with MBNL1 for the binding to CCUG repeats, releasing MBNL1 from sequestration in DM2 muscle cells.

Chantal Sellier
Estefanía Cerro-Herreros
Nicolas Charlet-Berguerand
ResearchOpen Access22 May 2018
Nature Communications

Volume: 9, P: 1-15
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

Endogenous and alcohol-derived acetaldehyde causes a specific pattern of DNA damage in haemopoietic stem cells; the effects are mitigated by detoxification, specific DNA repair mechanisms and a p53 response.

Juan I. Garaycoechea
Gerry P. Crossan
Ketan J. Patel
Research03 Jan 2018
Nature

Volume: 553, P: 171-177
Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site

Maud Kamal
Sonia Lameiras
Natalja ter Haar
ResearchOpen Access16 Nov 2020
British Journal of Cancer

Volume: 124, P: 777-785
Prognostic value of high-sensitivity measurable residual disease assessment after front-line chemoimmunotherapy in chronic lymphocytic leukemia

Rémi Letestu
Abdelmalek Dahmani
Henry Jardel
Research15 Sept 2020
Leukemia

Volume: 35, P: 1597-1609
Author Correction: Clinical phenotypes and outcomes associated with SARS-CoV-2 variant Omicron in critically ill French patients with COVID-19

Nicolas de Prost
Etienne Audureau
Slim Fourati
Amendments and CorrectionsOpen Access07 Dec 2022
Nature Communications

Volume: 13, P: 1
Pathological investigation of high pathogenicity avian influenza H5N8 in captive houbara bustards (Chlamydotis undulata), the United Arab Emirates 2020

Manuela Crispo
Mar Carrasco Muñoz
Guillaume Le Loc’h
ResearchOpen Access20 Feb 2024
Scientific Reports

Volume: 14, P: 1-10
Phylotranscriptomic consolidation of the jawed vertebrate timetree

The use of genomic data to reconstruct phylogenetic relationships is powerful but challenging. Here, the authors develop a bioinformatics pipeline and use phylogenomic datasets to reconstruct the evolutionary relationships of jawed vertebrates.

Iker Irisarri
Denis Baurain
Hervé Philippe
Research24 Jul 2017
Nature Ecology & Evolution

Volume: 1, P: 1370-1378
Phosphatidylinositol(4,5)bisphosphate coordinates actin-mediated mobilization and translocation of secretory vesicles to the plasma membrane of chromaffin cells

The role of phosphatidylinositol(4,5)bisphosphate in exocytosis is unclear. This study shows that inhibition of the p110δ isoform of PI3-kinase promotes a transient increase in phosphatidylinositol(4,5)bisphosphate, leading to a potentiation of exocytosis in chromaffin cells.

Peter J. Wen
Shona L. Osborne
Frédéric A. Meunier
Research04 Oct 2011
Nature Communications

Volume: 2, P: 1-11
The path to next-generation disease-modifying immunomodulatory combination therapies in Alzheimer’s disease

Looking beyond anti-amyloid immunotherapy in Alzheimer’s disease, the authors discuss innovative next-generation immunomodulatory combination therapies jointly targeting pathogenic proteins and peripheral–central immune crosstalk.

Marie Sarazin
Julien Lagarde
Guillaume Dorothée
Reviews05 Jun 2024
Nature Aging

Volume: 4, P: 761-770
A GDSL lipase-like from Ipomoea batatas catalyzes efficient production of 3,5-diCQA when expressed in Pichia pastoris

Miguel et al. identify a new enzyme belonging to the GDSL lipase-like family that is involved in the final stage of transformation of 5-CQA into 3,5-diCQA. This enzyme is able to realize an efficient transformation by over 60%, making the transformation process a valuable technological tool that can be easily transferred on an industrial scale.

Sissi Miguel
Guillaume Legrand
David Gagneul
ResearchOpen Access13 Nov 2020
Communications Biology

Volume: 3, P: 1-13
Association between antidepressant use and reduced risk of intubation or death in hospitalized patients with COVID-19: results from an observational study

Nicolas Hoertel
Marina Sánchez-Rico
Frédéric Limosin
Research04 Feb 2021
Molecular Psychiatry

Volume: 26, P: 5199-5212
Screening of dementia genes by whole-exome sequencing in early-onset Alzheimer disease: input and lessons

Gaël Nicolas
David Wallon
Didier Hannequin
Research05 Aug 2015
European Journal of Human Genetics

Volume: 24, P: 710-716
Genetic refinement and physical mapping of a chromosome 16q candidate region for inflammatory bowel disease

Habib Zouali
Mathias Chamaillard
Jean-Pierre Hugot
Research19 Oct 2001
European Journal of Human Genetics

Volume: 9, P: 731-742
Clustering of Crohn's disease within affected sibships

Jean-Pierre Hugot
Jean-Pierre Cézard
J Belaiche
Research14 Feb 2003
European Journal of Human Genetics

Volume: 11, P: 179-184
Nicotine dependence and incident psychiatric disorders: prospective evidence from US national study

Guillaume Airagnes
Marina Sánchez-Rico
Nicolas Hoertel
Research11 Sept 2024
Molecular Psychiatry

Volume: 30, P: 1080-1088
Cancer gene therapy mediated by CTS1, a p53 derivative: Advantage over wild-type p53 in growth inhibition of human tumors overexpressing MDM2

Cécile Bougeret
Angela Virone-Oddos
Thierry Huet
Research15 Jun 2000
Cancer Gene Therapy

Volume: 7, P: 789-798
The neurodevelopmental and facial phenotype in individuals with a TRIP12 variant

Mio Aerden
Anne-Sophie Denommé-Pichon
Hilde Van Esch
Research07 Feb 2023
European Journal of Human Genetics

Volume: 31, P: 461-468
Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics

Malissen and colleagues provide a quantitative systems-level analysis of 15 distinct signalosomes that form within minutes of TCR stimulation of primary CD4⁺ T cells.

Guillaume Voisinne
Kristof Kersse
Bernard Malissen
Research07 Oct 2019
Nature Immunology

Volume: 20, P: 1530-1541
In situ brain tumor detection using a Raman spectroscopy system—results of a multicenter study

Katherine Ember
Frédérick Dallaire
Kevin Petrecca
ResearchOpen Access10 Jun 2024
Scientific Reports

Volume: 14, P: 1-12
Physical exertion at work and addictive behaviors: tobacco, cannabis, alcohol, sugar and fat consumption: longitudinal analyses in the CONSTANCES cohort

Nadine Hamieh
Alexis Descatha
Guillaume Airagnes
ResearchOpen Access13 Jan 2022
Scientific Reports

Volume: 12, P: 1-9
A lyophilised formulation of chimpanzee adenovirus vector for long-term stability outside the deep-freeze cold chain

Mathot et al. assess stability of an adenovirus-based vaccine vector lyophilized and stored long-term. The stability of the vaccine remains within an acceptable limit after five years of storage, and the protective capacity of the vaccine in a mouse model of virus-challenge is unaltered after two years of storage.

Frédéric Mathot
Edwige Lefebvre
Erwan Bourlès
ResearchOpen Access18 Jan 2025
Communications Medicine

Volume: 5, P: 1-9
Combined Earth observations reveal the sequence of conditions leading to a large algal bloom in Lake Geneva

A large algal bloom in Lake Geneva in 2021 was triggered by a sequence of heavy rainfall followed by wind-induced coastal upwelling, and a prolonged period of warm, calm weather, according to a combination of satellite remote sensing, in-situ measurements and three-dimensional numerical modeling.

Abolfazl Irani Rahaghi
Daniel Odermatt
Damien Bouffard
ResearchOpen Access01 May 2024
Communications Earth & Environment

Volume: 5, P: 1-12
Further delineation of the SCAF4-associated neurodevelopmental disorder

Cosima M. Schmid
Anne Gregor
Christiane Zweier
ResearchOpen Access12 Dec 2024
European Journal of Human Genetics

Volume: 33, P: 588-594
Comparison of mortality and outcomes of four respiratory viruses in the intensive care unit: a multicenter retrospective study

Baptiste Grangier
Charles-Hervé Vacheron
Olivia Vassal
ResearchOpen Access20 Mar 2024
Scientific Reports

Volume: 14, P: 1-8
Retention rate of subcutaneous TNF inhibitors in axial spondyloarthritis in a multicentre study from the RIC-FRANCE network

Guillaume Larid
Guy Baudens
Elisabeth Gervais
ResearchOpen Access16 Jan 2024
Scientific Reports

Volume: 14, P: 1-12
Expert elicitation of state shifts and divergent sensitivities to climate warming across northern ecosystems

Warming-induced changes in permafrost, peatlands, lakes, snowpack, vegetation, and vertebrates could impact northern ecosystem integrity, with different response times across components and latitude, according to an expert assessment of sensitivity in northern landscapes.

Émilie Saulnier-Talbot
Éliane Duchesne
Joël Bêty
ResearchOpen Access25 Oct 2024
Communications Earth & Environment

Volume: 5, P: 1-15
RETRACTED ARTICLE: Culture of previously uncultured members of the human gut microbiota by culturomics

Optimization of culturing techniques has allowed the identification of 1,057 prokaryotic species within the human gut microbiome repertoire, doubling the previous number of isolated species from the human gut.

Jean-Christophe Lagier
Saber Khelaifia
Didier Raoult
ResearchOpen Access07 Nov 2016
Nature Microbiology

Volume: 1, P: 1-8
Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci

Stuart Orkin, Daniel Bauer and colleagues present DNA Striker, a computational tool to design variant-aware saturating-mutagenesis screens with multiple CRISPR-associated nucleases. They apply their methodology to the HBS1L-MYB intergenic region, which is associated with red-blood-cell traits, and identify putative regulatory elements that control MYB expression.

Matthew C Canver
Samuel Lessard
Stuart H Orkin
Research20 Feb 2017
Nature Genetics

Volume: 49, P: 625-634
Extended-depth of field random illumination microscopy, EDF-RIM, provides super-resolved projective imaging

Lorry Mazzella
Thomas Mangeat
Loïc LeGoff
ResearchOpen Access10 Oct 2024
Light: Science & Applications

Volume: 13, P: 1-12
The central role of self-esteem in the quality of life of patients with mental disorders

Guillaume Barbalat
Julien Plasse
Nicolas Franck
ResearchOpen Access12 May 2022
Scientific Reports

Volume: 12, P: 1-10
36-month durability of ultrasound renal denervation for hypertension resistant to combination therapy in RADIANCE-HTN TRIO

Michael J. Bloch
Ajay J. Kirtane
Patric Kröpil
ResearchOpen Access27 Sept 2024
Hypertension Research

Volume: 47, P: 3467-3472
FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells

Nadia Habel
Najla El-Hachem
Robert Ballotti
ResearchOpen Access18 Jan 2021
Cell Death & Differentiation

Volume: 28, P: 1837-1848
Genomic profiling of small bowel adenocarcinoma: a pooled analysis from 3 databases

Thomas Aparicio
Julie Henriques
Pierre Laurent Puig
Research14 May 2024
British Journal of Cancer

Volume: 131, P: 49-62
Uncovering and deciphering the pro-invasive role of HACE1 in melanoma cells

Najla El-Hachem
Nadia Habel
Robert Ballotti
Research07 Mar 2018
Cell Death & Differentiation

Volume: 25, P: 2010-2022
Reorganization of Asian climate in relation to Tibetan Plateau uplift

Asian Monsoon initiation is thought to be related to Tibetan Plateau uplift, but the timings and mechanisms are debated. This Review discusses a two-stage development of the Asian Monsoon: northward expansion ~41 million years ago (Ma), and attainment of a modern-like pattern at ~26 Ma.

Fuli Wu
Xiaomin Fang
Wenxia Han
Reviews20 Sept 2022
Nature Reviews Earth & Environment

Volume: 3, P: 684-700
A new bio imagery user-friendly tool for automatic morphometry measurement on muscle cell cultures and histological sections

Aurélien Brun
Guillaume Mougeot
Marine Gueugneau
ResearchOpen Access07 Feb 2024
Scientific Reports

Volume: 14, P: 1-13
Sounds as taxonomic indicators in Holocentrid fishes

Marine Banse
Estelle Bertimes
Eric Parmentier
ResearchOpen Access05 Nov 2024
npj Biodiversity

Volume: 3, P: 1-14
Influence of diet on acute endocannabinoidome mediator levels post exercise in active women, a crossover randomized study

Fabiola Forteza
Isabelle Bourdeau-Julien
Frédéric Raymond
ResearchOpen Access20 May 2022
Scientific Reports

Volume: 12, P: 1-13
Selection of a novel strain of Christensenella minuta as a future biotherapy for Crohn’s disease

Karima Relizani
Katy Le Corf
Sandrine P. Claus
ResearchOpen Access11 Apr 2022
Scientific Reports

Volume: 12, P: 1-15
Discovery of a new molecule inducing melanoma cell death: dual AMPK/MELK targeting for novel melanoma therapies

Emilie Jaune
Elisa Cavazza
Stéphane Rocchi
ResearchOpen Access11 Jan 2021
Cell Death & Disease

Volume: 12, P: 1-20
Benefits from one session of deep and slow breathing on vagal tone and anxiety in young and older adults

Valentin Magnon
Frédéric Dutheil
Guillaume T. Vallet
ResearchOpen Access29 Sept 2021
Scientific Reports

Volume: 11, P: 1-10
Author Correction: Expert elicitation of state shifts and divergent sensitivities to climate warming across northern ecosystems

Émilie Saulnier-Talbot
Éliane Duchesne
Joël Bêty
Amendments and CorrectionsOpen Access26 Dec 2024
Communications Earth & Environment

Volume: 5, P: 1
The inhibitory receptor CD94/NKG2A on CD8⁺ tumor-infiltrating lymphocytes in colorectal cancer: a promising new druggable immune checkpoint in the context of HLAE/β2m overexpression

Juliette Eugène
Nicolas Jouand
Céline Bossard
Research13 Aug 2019
Modern Pathology

Volume: 33, P: 468-482
SUGT1 controls susceptibility to HIV-1 infection by stabilizing microtubule plus-ends

Awatef Allouch
Cristina Di Primio
Jean-Luc Perfettini
Research08 Jun 2020
Cell Death & Differentiation

Volume: 27, P: 3243-3257
POLR1B and neural crest cell anomalies in Treacher Collins syndrome type 4

Elodie Sanchez
Béryl Laplace-Builhé
David Geneviève
ResearchOpen Access24 Oct 2019
Genetics in Medicine

Volume: 22, P: 547-556
Low fibrosis biomarker levels predict cardiac resynchronization therapy response

Grégoire Massoullié
Vincent Sapin
Romain Eschalier
ResearchOpen Access15 Apr 2019
Scientific Reports

Volume: 9, P: 1-9
Insight into the dual function of lipid phosphate phosphatase PgpB involved in two essential cell-envelope metabolic pathways in Escherichia coli

Xudong Tian
Rodolphe Auger
Thierry Touzé
ResearchOpen Access06 Aug 2020
Scientific Reports

Volume: 10, P: 1-15
The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim

Lazaro E. Aira
Elodie Villa
Sandrine Marchetti
Research02 Feb 2018
Oncogene

Volume: 37, P: 2122-2136

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