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Showing 1–11 of 11 results
Advanced filters: Author: Francis G. Woodhouse Clear advanced filters
  • Active fluids consist of self-driven particles that can drive spontaneous flow without the intervention of external forces. Here Woodhouseet al. show how to design logic circuits using this phenomenon in active fluid networks, which could be further exploited for autonomous microfluidic computing.

    • Francis G. Woodhouse
    • Jörn Dunkel
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-7
  • Hydrodynamic coupling induces a vortex state in bacterial populations. Microfluidic experiments and modelling now demonstrate that lattices of these vortices can self-organize into patterns characterized by ferro- and antiferromagnetic order.

    • Hugo Wioland
    • Francis G. Woodhouse
    • Raymond E. Goldstein
    Research
    Nature Physics
    Volume: 12, P: 341-345
  • The PSA (KLK3) genetic variant rs17632542 is associated with reduced prostate cancer risk and lower serum PSA levels, although the underlying reasons are unclear. Here, the authors show that this PSA variant reduced proteolytic activity and leads to smaller tumours, but also increases invasion and bone metastasis, indicating its dual risk association depending on tumour context; the variant is associated with both lower risk and poor clinical outcomes.

    • Srilakshmi Srinivasan
    • Thomas Kryza
    • Jyotsna Batra
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-21
  • Reconstructing system dynamics on complex high-dimensional energy landscapes from static experimental snapshots remains challenging. Here, the authors introduce a framework to infer the essential dynamics of physical and biological systems without need for time-dependent measurements.

    • Philip Pearce
    • Francis G. Woodhouse
    • Jörn Dunkel
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-8
  • Ray Ming, Robert Paull, Qingyi Yu and colleagues report the genome sequences of two cultivated pineapple varieties and one wild pineapple relative. Their analysis supports the use of the pineapple as a reference genome for monocot comparative genomics and provides insight into the evolution of crassulacean acid metabolism photosynthesis.

    • Ray Ming
    • Robert VanBuren
    • Qingyi Yu
    ResearchOpen Access
    Nature Genetics
    Volume: 47, P: 1435-1442
  • Syncrip is a conserved RNA-binding protein that mediates selective miRNA loading into cell-secreted exosomes, which is important for cell–cell communication. Here the authors provide mechanistic insights into how Syncrip recognises its target miRNAs by combining NMR and crystallography.

    • Fruzsina Hobor
    • Andre Dallmann
    • Andres Ramos
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-16
  • Cell-in-cell (CIC) structures are frequently observed in cancers; however, it is unclear how their formation contributes to tumorigenesis. Here, the authors show that the high frequency of CIC is linked to mutant p53 status and CIC containing p53 mutant cancer cells are pro-tumorigenic due to enhanced genomic instability.

    • Hannah L. Mackay
    • David Moore
    • Patricia A. J. Muller
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15
  • Understanding the motion of finite-sized particles in crowded environments is at the heart of important biological and physiological problems. Here, the authors construct a network-based mathematical framework for studying transport of macromolecules within crowded heterogeneous environments, such as the intracellular environment, and probe the interconnection of crowding and geometry upon macromolecular transport.

    • Daniel B. Wilson
    • Francis. G. Woodhouse
    • Ruth E. Baker
    ResearchOpen Access
    Communications Physics
    Volume: 4, P: 1-14