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Oncogene (10)
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Showing 1–33 of 33 results

Advanced filters: Author: G D'Orazi Clear advanced filters

HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function

Valeria Di Stefano
Giovanni Blandino
Gabriella D'Orazi
Research03 May 2004
Oncogene

Volume: 23, P: 5185-5192
HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21^Waf1 after nonapoptotic DNA damage

Valeria Di Stefano
Silvia Soddu
Gabriella D'Orazi
Research09 May 2005
Oncogene

Volume: 24, P: 5431-5442
Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells

R Puca
L Nardinocchi
G D'Orazi
Reviews31 May 2010
Oncogene

Volume: 29, P: 4378-4387
PRIMA-1^MET induces nucleolar accumulation of mutant p53 and PML nuclear body-associated proteins

N Rökaeus
G Klein
K Mattsson
Research14 Aug 2006
Oncogene

Volume: 26, P: 982-992
The human protein kinase HIPK2 phosphorylates and downregulates the methyl-binding transcription factor ZBTB4

D Yamada
R Pérez-Torrado
P -A Defossez
Research18 May 2009
Oncogene

Volume: 28, P: 2535-2544
Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma

J-H Mao
D Wu
A Balmain
ResearchOpen Access25 Jul 2011
Oncogene

Volume: 31, P: 1176-1180
Silicate clouds and a circumplanetary disk in the YSES-1 exoplanet system

Direct observations of silicate clouds in the atmosphere of the exoplanet YSES-1 c and the first circumplanetary disk silicate emission around its sibling planet YSES-1 b are reported.

K. K. W. Hoch
M. Rowland
Y. Zhang
Research10 Jun 2025
Nature

Volume: 643, P: 938-942
Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression

Andreas Möller
Hüseyin Sirma
M Lienhard Schmitz
Research27 Nov 2003
Oncogene

Volume: 22, P: 8731-8737
Human neocortical expansion involves glutamatergic neuron diversification

Combined patch clamp recording, biocytin staining and single-cell RNA-sequencing of human neurocortical neurons shows an expansion of glutamatergic neuron types relative to mouse that characterizes the greater complexity of the human neocortex.

Jim Berg
Staci A. Sorensen
Ed S. Lein
ResearchOpen Access06 Oct 2021
Nature

Volume: 598, P: 151-158
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis

Gabriella D'Orazi
Barbara Cecchinelli
Silvia Soddu
Research03 Dec 2001
Nature Cell Biology

Volume: 4, P: 11-19
Author Correction: Human neocortical expansion involves glutamatergic neuron diversification

Jim Berg
Staci A. Sorensen
Ed S. Lein
Amendments and CorrectionsOpen Access06 Jan 2022
Nature

Volume: 601, P: E12
A multimodal cell census and atlas of the mammalian primary motor cortex

The BRAIN Initiative Cell Census Network has constructed a multimodal cell census and atlas of the mammalian primary motor cortex in a landmark effort towards understanding brain cell-type diversity, neural circuit organization and brain function.

Edward M. Callaway
Hong-Wei Dong
Susan Sunkin
ResearchOpen Access06 Oct 2021
Nature

Volume: 598, P: 86-102
A plague of magnetic spots among the hot stars of globular clusters

Two sources of variability are reported in extreme horizontal branch (EHB) stars found in globular clusters, both related to the action of weak magnetic fields: large surface spots and very energetic flares. EHB stars in clusters can thus be linked to EHB field stars, and beyond, to other stars with radiative envelopes.

Y. Momany
S. Zaggia
Y. Beletsky
Research01 Jun 2020
Nature Astronomy

Volume: 4, P: 1092-1101
Imbalance Between Matrix Metalloproteinase (MMPs) and their Inhibitors in BALs of Mechanically Ventilated Neonates † 1704

E Messina
R Lisio
M Orzalesi
Research01 Apr 1998
Pediatric Research

Volume: 43, P: 291
Rapid contraction of giant planets orbiting the 20-million-year-old star V1298 Tau

The 20-million-year-old, solar-type star V1298 Tau hosts a multiplanet system. The two outermost planets, gas giants with masses of 0.64 and 1.16 Jupiter masses, respectively, defy current formation models as their mass–radius relationship should be reached much later in the stages of planetary evolution.

A. Suárez Mascareño
M. Damasso
M. Mallonn
Research02 Dec 2021
Nature Astronomy

Volume: 6, P: 232-240
Mapping of shadows cast on a protoplanetary disk by a close binary system

Moving shadows have been seen on the circumbinary disk around V4046 Sgr, cast by eclipses of the central binary system. Using geometrical arguments, the degree of flaring of the disk and the distance to the system have been calculated.

V. D’Orazi
R. Gratton
A. Zurlo
Research26 Nov 2018
Nature Astronomy

Volume: 3, P: 167-172
Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas

P A Forsyth
H Wong
D R Edwards
ResearchOpen Access12 Mar 1999
British Journal of Cancer

Volume: 79, P: 1828-1835
Degradation of mutant p53H175 protein by Zn(II) through autophagy

A Garufi
D Pucci
G D’Orazi
ResearchOpen Access29 May 2014
Cell Death & Disease

Volume: 5, P: e1271
relA over-expression reduces tumorigenicity and activates apoptosis in human cancer cells

A Ricca
A Biroccio
D Del Bufalo
ResearchOpen Access11 Dec 2001
British Journal of Cancer

Volume: 85, P: 1914-1921
Wild-type p53-mediated down-modulation of interleukin 15 and interleukin 15 receptors in human rhabdomyosarcoma cells

C De Giovanni
P Nanni
P-L Lollini
Research01 Dec 1998
British Journal of Cancer

Volume: 78, P: 1541-1546
Interferons α and γ induce p53-dependent and p53-independent apoptosis, respectively

Chiara Porta
Reda Hadj-Slimane
Mounira K Chelbi-Alix
Research06 Dec 2004
Oncogene

Volume: 24, P: 605-615
Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma

J de Lange
L V Ly
A G Jochemsen
Research18 Jul 2011
Oncogene

Volume: 31, P: 1105-1116
KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 α-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression

Maria Saveria Gilardini Montani
Luca Falcinelli
Mara Cirone
ResearchOpen Access18 May 2020
British Journal of Cancer

Volume: 123, P: 298-306
Erratum: HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma

M Granato
V Lacconi
M Cirone
Amendments and Corrections22 May 2014
Cell Death & Disease

Volume: 5, P: e1254
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress

Rossella Benedetti
Maria Anele Romeo
Mara Cirone
ResearchOpen Access25 Jun 2022
Cell Death Discovery

Volume: 8, P: 1-12
ZnCl₂ sustains the adriamycin-induced cell death inhibited by high glucose

A Garufi
D Trisciuoglio
G D'Orazi
ResearchOpen Access30 Jun 2016
Cell Death & Disease

Volume: 7, P: e2280
Targeting MKK3 as a novel anticancer strategy: molecular mechanisms and therapeutical implications

S Baldari
V Ubertini
G Bossi
ResearchOpen Access29 Jan 2015
Cell Death & Disease

Volume: 6, P: e1621
p53 can inhibit cell proliferation through caspase-mediated cleavage of ERK2/MAPK

A Marchetti
B Cecchinelli
S Soddu
Research02 Jan 2004
Cell Death & Differentiation

Volume: 11, P: 596-607
Glucose restriction induces cell death in parental but not in homeodomain-interacting protein kinase 2-depleted RKO colon cancer cells: molecular mechanisms and implications for tumor therapy

A Garufi
A Ricci
G D′Orazi
ResearchOpen Access23 May 2013
Cell Death & Disease

Volume: 4, P: e639
HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma

M Granato
V Lacconi
M Cirone
ResearchOpen Access18 Jul 2013
Cell Death & Disease

Volume: 4, P: e730
HIPK2-induced p53Ser46 phosphorylation activates the KILLER/DR5-mediated caspase-8 extrinsic apoptotic pathway

G Pistritto
R Puca
G D'Orazi
Correspondence13 Jul 2007
Cell Death & Differentiation

Volume: 14, P: 1837-1839
Increase of BCNU sensitivity by wt-p53 gene therapy in glioblastoma lines depends on the administration schedule

A Biroccio
D Del Bufalo
G Zupi
Research25 Jun 1999
Gene Therapy

Volume: 6, P: 1064-1072
Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist

V Ubertini
G Norelli
G Bossi
Research07 Jul 2014
Oncogene

Volume: 34, P: 2493-2504

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HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function

HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21^Waf1 after nonapoptotic DNA damage

Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells

PRIMA-1^MET induces nucleolar accumulation of mutant p53 and PML nuclear body-associated proteins

The human protein kinase HIPK2 phosphorylates and downregulates the methyl-binding transcription factor ZBTB4

Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma

Silicate clouds and a circumplanetary disk in the YSES-1 exoplanet system

Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression

Human neocortical expansion involves glutamatergic neuron diversification

Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis

Author Correction: Human neocortical expansion involves glutamatergic neuron diversification

A multimodal cell census and atlas of the mammalian primary motor cortex

A plague of magnetic spots among the hot stars of globular clusters

Imbalance Between Matrix Metalloproteinase (MMPs) and their Inhibitors in BALs of Mechanically Ventilated Neonates † 1704

Rapid contraction of giant planets orbiting the 20-million-year-old star V1298 Tau

Mapping of shadows cast on a protoplanetary disk by a close binary system

Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas

Degradation of mutant p53H175 protein by Zn(II) through autophagy

relA over-expression reduces tumorigenicity and activates apoptosis in human cancer cells

Wild-type p53-mediated down-modulation of interleukin 15 and interleukin 15 receptors in human rhabdomyosarcoma cells

Interferons α and γ induce p53-dependent and p53-independent apoptosis, respectively

Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma

KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 α-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression

Erratum: HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma

ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress

ZnCl₂ sustains the adriamycin-induced cell death inhibited by high glucose

Targeting MKK3 as a novel anticancer strategy: molecular mechanisms and therapeutical implications

p53 can inhibit cell proliferation through caspase-mediated cleavage of ERK2/MAPK

Glucose restriction induces cell death in parental but not in homeodomain-interacting protein kinase 2-depleted RKO colon cancer cells: molecular mechanisms and implications for tumor therapy

HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma

HIPK2-induced p53Ser46 phosphorylation activates the KILLER/DR5-mediated caspase-8 extrinsic apoptotic pathway

Increase of BCNU sensitivity by wt-p53 gene therapy in glioblastoma lines depends on the administration schedule

Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist

Search

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