The idea of carbon–hydrogen functionalization, in which C–H bonds are modified at will, represents a paradigm shift in the standard logic of organic synthesis; here, dirhodium catalysts are used to achieve highly site-selective, diastereoselective and enantioselective C–H functionalization of n-alkanes and terminally substituted n-alkyl compounds.
- Kuangbiao Liao
- Solymar Negretti
- Huw M. L. Davies
