Nature Search

Pervasive conformational fluctuations on microsecond time scales in a fibronectin type III domain

Mikael Akke
Jun Liu
Arthur G. Palmer III
Research01 Jan 1998
Nature Structural Biology

Volume: 5, P: 55-59
High-resolution epidemiological landscape from ~290,000 SARS-CoV-2 genomes from Denmark

A high proportion of confirmed SARS-CoV-2 cases in Denmark were sequenced during the pandemic and linked to demographic, spatial and temporal data. Here, the authors analyse 290,000 genomes sampled in 2021 to demonstrate the value of this high coverage, detailed data set.

Mark P. Khurana
Jacob Curran-Sebastian
Samir Bhatt
ResearchOpen Access20 Aug 2024
Nature Communications

Volume: 15, P: 1-16
Phase transitions in random circuit sampling

By implementing random circuit sampling, experimental and theoretical results establish the existence of transitions to a stable, computationally complex phase that is reachable with current quantum processors.

A. Morvan
B. Villalonga
S. Boixo
ResearchOpen Access09 Oct 2024
Nature

Volume: 634, P: 328-333
Stimulatory capacity of human T and B lymphocytes in the mixed leukocyte culture

HANS-PETER LOHRMANN
LIGITA NOVIKOVS
ROBERT G. GRAW JUN.
Research12 Jul 1974
Nature

Volume: 250, P: 144-146
Artefacts produced from 3-Iodo-Tyrosine and 3 : 5-Di-iodo-Tyrosine by Heating with Alkali

P. G. STANLEY
Research23 May 1953
Nature

Volume: 171, P: 933-934
Liquid carbon dioxide of magmatic origin and its role in volcanic eruptions

Allan R. Chivas
Ivan Barnes
John O. Stone
Research09 Apr 1987
Nature

Volume: 326, P: 587-589
Initial cosmetic outcome six months after kilovoltage therapy of facial basal cell carcinoma: A Danish national prospective study of 932 patients

O.N Braendstrup
P Lassen
J.G Eriksen
ResearchOpen Access29 May 2025
Scientific Reports

Volume: 15, P: 1-7
Leishmania genetic exchange is mediated by IgM natural antibodies

Genetic exchange of Leishmania parasites in the sand fly host is mediated by natural IgM antibodies, providing insights that will help generate reproducible and increased recovery of backcrosses for research purposes.

Tiago D. Serafim
Eva Iniguez
Jesus G. Valenzuela
Research25 Oct 2023
Nature

Volume: 623, P: 149-156
K-ras mutations and HLA-DR expression in large bowel adenomas

S Norheim Andersen
J Breivik
TO Rognum
Research01 Jul 1996
British Journal of Cancer

Volume: 74, P: 99-108
Risks from transgenic crops

A. M. Timmons
Y. M. Charters
M. J. Wilkinson
Research11 Apr 1996
Nature

Volume: 380, P: 487
Optical Activity in Saponified Organic Matter Isolated from the Interior of the Orgueil Meteorite

BARTHOLOMEW NAGY
MARY T. J. MURPHY
FRANCO GAZZARRINI
Research18 Apr 1964
Nature

Volume: 202, P: 228-233
Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c

Analysis of HbA1c and FPG levels across 117 population-based studies demonstrates regional variation in prevalence of previously undiagnosed screen-detected diabetes using one or both measures and suggests that use of elevated FPG alone could underestimate diabetes prevalence in low- and middle-income countries.

Bin Zhou
Kate E. Sheffer
Majid Ezzati
ResearchOpen Access09 Nov 2023
Nature Medicine

Volume: 29, P: 2885-2901
High-potency ligands for DREADD imaging and activation in rodents and monkeys

Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are a powerful tool for neuroscience, but the standard DREADD ligand, CNO, has significant drawbacks. Here the authors report two novel high-potency DREADD ligands and a novel DREADD radiotracer for imaging purposes.

Jordi Bonaventura
Mark A. G. Eldridge
Michael Michaelides
ResearchOpen Access11 Oct 2019
Nature Communications

Volume: 10, P: 1-12
Near-edge X-ray absorption spectra for metallic Cu and Mn

G. N. Greaves
P. J. Durham
P. Quinn
Research12 Nov 1981
Nature

Volume: 294, P: 139-142
A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C

mRNA deadenylation, the first step in regulated degradation, is mediated by the action of the CCR4-NOT and PAN2-PAN3 complexes. Here the authors show that the RNA-binding E3 ubiquitin-ligase MEX-3C associates with the CCR4-NOT complex and ubiquitinates the catalytic subunit CNOT7 to regulate its deadenylation activity.

Florencia Cano
Radu Rapiteanu
Paul J. Lehner
ResearchOpen Access16 Oct 2015
Nature Communications

Volume: 6, P: 1-8
Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis

Roquin is an RNA-binding protein that promotes the degradation of specific mRNAs and is crucial for the maintenance of peripheral immune tolerance. Here the authors show that, in addition to its target mRNAs, Roquin can bind miR-146a and the RISC component Ago2 to control homeostasis of both RNA species.

Monika Srivastava
Guowen Duan
Carola G. Vinuesa
ResearchOpen Access20 Feb 2015
Nature Communications

Volume: 6, P: 1-13
Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans

The genomes of 609 wild Caenorhabditis elegans strains isolated across the world reveal hyper-divergent regions, often shared among many wild strains, that are enriched for genes that mediate environmental response, which might have enabled the species to thrive in diverse environments.

Daehan Lee
Stefan Zdraljevic
Erik C. Andersen
Research05 Apr 2021
Nature Ecology & Evolution

Volume: 5, P: 794-807
Carcinogenic action of 4-acetamidostilbene and the N-hydroxy derivative in the rat

R W Baldwin
G J Cunningham
S J Surtees
Research01 Mar 1968
British Journal of Cancer

Volume: 22, P: 133-144
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

A region on chromosome 19p13 is associated with the risk of developing ovarian and breast cancer. Here, the authors genotyped SNPs in this region in thousands of breast and ovarian cancer patients and identified SNPs associated with three genes, which were analysed with functional studies.

Kate Lawrenson
Siddhartha Kar
Simon A. Gayther
ResearchOpen Access07 Sept 2016
Nature Communications

Volume: 7, P: 1-22
“30 years of global collaboration in transplantation and cellular therapy: WMDA’s commitment to donor safety, ethical standards, and equitable access”

L. M. Foeken
J. A. Feinberg
M. Seftel
ReviewsOpen Access26 Sept 2025
Bone Marrow Transplantation

P: 1-6
Isolation, synthesis and bioactivity studies of phomactin terpenoids

Natural product chemistry remains critical to the discovery of small molecules that possess unique bioactivities. A collaborative approach to studying the phomactin diterpenoid family that spans isolation, chemical synthesis and investigation of their bioactivity is now reported. The novel congeners that were isolated inspired a divergent strategy to achieve their practical preparation and their anti-tumour evaluation.

Yusuke Kuroda
Karen J. Nicacio
Richmond Sarpong
Research30 Jul 2018
Nature Chemistry

Volume: 10, P: 938-945
A New Embedding Medium for Electron Microscopy

AUDREY M. GLAUERT
G. E. ROGERS
R. H. GLAUERT
Research13 Oct 1956
Nature

Volume: 178, P: 803
Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI

Catheter-associated urinary tract infections can often lead to secondary bloodstream infections, and catheter-induced bladder inflammation. In this work, authors utilise murine models to probe defective fibrinolysis drives extravascular fibrin formation, potentially predisposing hosts to severe CAUTI.

Jonathan J. Molina
Kurt N. Kohler
Ana L. Flores-Mireles
ResearchOpen Access27 Mar 2024
Nature Communications

Volume: 15, P: 1-16
Genomic epidemiology reveals multiple introductions of Zika virus into the United States

Genome sequencing of Zika virus samples from infected patients and Aedes aegypti mosquitoes in Florida shows that the virus was probably introduced into the United States on multiple occasions, and that the Caribbean is the most likely source.

Nathan D. Grubaugh
Jason T. Ladner
Kristian G. Andersen
Research24 May 2017
Nature

Volume: 546, P: 401-405
Validity of a questionnaire to assess fruit and vegetable intake in adults

A G Kristjansdottir
L F Andersen
I Thorsdottir
Research23 Nov 2005
European Journal of Clinical Nutrition

Volume: 60, P: 408-415
Induction of Sexual Excitement by the Action of Adrenocorticotrophic Hormone in Brain

A. BERTOLINI
W. VERGONI
W. FERRARI
Research15 Feb 1969
Nature

Volume: 221, P: 667-669
Pattern of extinction of the woolly mammoth in Beringia

Beringian mammoths were abundant 45,000 to 30,000 years ago, but then experienced a long decline in concert with changes in climate, habitat and human presence. This study uses¹⁴C dating to trace their spatio temporal pattern of extinction until the loss of final island populations about 4,000 years ago.

G.M. MacDonald
D.W. Beilman
B. Van Valkenburgh
ResearchOpen Access12 Jun 2012
Nature Communications

Volume: 3, P: 1-8
A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease

Results from the phase 2/3 clinical trial of gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease reveal no beneficial effects on cognitive measures despite a significant reduction in amyloid plaques and other key biomarkers in those treated with gantenerumab.

Stephen Salloway
Martin Farlow
Christopher H. van Dyck
Research21 Jun 2021
Nature Medicine

Volume: 27, P: 1187-1196
Secondary anionic phospholipid binding site and gating mechanism in Kir2.1 inward rectifier channels

Inwardly rectifying potassium channels require interactions with both PI(4,5)P₂ and a second anionic phospholipid for full activation. Lee et al. locate the secondary anionic phospholipid-binding site in Kir2.1 and reveal how it synergistically promotes PI(4,5)P₂sensitivity.

Sun-Joo Lee
Shizhen Wang
Colin G. Nichols
ResearchOpen Access25 Nov 2013
Nature Communications

Volume: 4, P: 1-12
Degree of Weathering of Soils

G. W. ROBINSON
MINNIE RICHARDSON
Research16 Apr 1932
Nature

Volume: 129, P: 581-582
Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth

Chijen Lin
Sheng-Cai Lin
Michael G. Rosenfeld
Research31 Dec 1992
Nature

Volume: 360, P: 765-768
Repositioning of the global epicentre of non-optimal cholesterol

From 1980 to 2018, the levels of total and non-high-density lipoprotein cholesterol increased in low- and middle-income countries, especially in east and southeast Asia, and decreased in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe.

Cristina Taddei
Bin Zhou
Majid Ezzati
ResearchOpen Access03 Jun 2020
Nature

Volume: 582, P: 73-77
Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine

The authors have previously demonstrated the neutralising capacity of their nanoparticle vaccine, as well as showing protection of non-human primates from SARS-CoV-2 WA-1 infection. In this work, they investigate the ability of their vaccine candidate to neutralise SARS-CoV-2 variants of concern, and protect animals from other sarbecoviruses.

Dapeng Li
David R. Martinez
Barton F. Haynes
ResearchOpen Access23 Oct 2022
Nature Communications

Volume: 13, P: 1-15
Purification-based quantum error mitigation of pair-correlated electron simulations

It is hoped that simulations of molecules and materials will provide a near-term application of quantum computers. A study of the performance of error mitigation highlights the obstacles to scaling up these calculations to practically useful sizes.

T. E. O’Brien
G. Anselmetti
N. C. Rubin
ResearchOpen Access12 Oct 2023
Nature Physics

Volume: 19, P: 1787-1792
Possible heterogeneity of the Earth's core deduced from PKIKP travel times

G. Poupinet
R. Pillet
A. Souriau
Research15 Sept 1983
Nature

Volume: 305, P: 204-206
Double-Q spin-density wave in iron arsenide superconductors

A combination of neutron scattering, X-ray scattering and Mössbauer spectroscopy experiments reveal the existence of a collinear double-Q magnetic ordering in an iron arsenide superconductor.

J. M. Allred
K. M. Taddei
R. Osborn
Research25 Jan 2016
Nature Physics

Volume: 12, P: 493-498
Formation of robust bound states of interacting microwave photons

An experimental investigation of the dynamics of the spin ½ Floquet XXZ model finds bound states as predicted, and also robustness to noise and non-integrability when theoretical descriptions start to fail.

A. Morvan
T. I. Andersen
P. Roushan
ResearchOpen Access07 Dec 2022
Nature

Volume: 612, P: 240-245
Single-cell and spatial multi-omics highlight effects of anti-integrin therapy across cellular compartments in ulcerative colitis

Anti-integrin therapy inhibits lymphocyte trafficking in ulcerative colitis. Here Mennillo et al. use single-cell and spatial -omics to show modulation of mononuclear phagocytes and other networks, identifying gene sets related to treatment response.

Elvira Mennillo
Yang Joon Kim
Michael G. Kattah
ResearchOpen Access19 Feb 2024
Nature Communications

Volume: 15, P: 1-19
Isolation of infective tomato bushy stunt virus after passage through the human alimentary tract

J. A. Tomlinson
Elizabeth Faithfull
G. Beards
Research16 Dec 1982
Nature

Volume: 300, P: 637-638
Knocking out the LRRK2 gene increases sensitivity to wavelength information in rats

Freja Gam Østergaard
ResearchOpen Access29 Feb 2024
Scientific Reports

Volume: 14, P: 1-13
mRNA-1273 protects against SARS-CoV-2 beta infection in nonhuman primates

The beta variant (B.1.351) is to date the most resistant to neutralization of the SARS-CoV-2 variants. Using nonhuman primates, Seder and colleagues demonstrate that double vaccination with a high dose of the lipid nanoparticle vaccine mRNA-1273 protects against infection with the beta variant.

Kizzmekia S. Corbett
Anne P. Werner
Robert A. Seder
Research20 Aug 2021
Nature Immunology

Volume: 22, P: 1306-1315
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

A cross-ancestry genome-wide association meta-analysis of amyotrophic lateral sclerosis (ALS) including 29,612 patients with ALS and 122,656 controls identifies 15 risk loci with distinct genetic architectures and neuron-specific biology.

Wouter van Rheenen
Rick A. A. van der Spek
Jan H. Veldink
ResearchOpen Access06 Dec 2021
Nature Genetics

Volume: 53, P: 1636-1648
Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential

The half-life of IgG is regulated by binding to the neonatal Fc receptor and, in the case of IgG3, is reduced compared to other IgG proteins. In this study, a mutation in IgG3 is shown to reduce binding to the neonatal Fc receptor, which can be competitively blocked by IgG1.

Nigel M. Stapleton
Jan Terje Andersen
Gestur Vidarsson
ResearchOpen Access20 Dec 2011
Nature Communications

Volume: 2, P: 1-9
Solar cycle relationship clouded by Neptune's sustained brightness maximum

G. W. Lockwood
D. T. Thompson
Research14 Feb 1991
Nature

Volume: 349, P: 593-594
The metabolism of 4-acetamidostilbene and its N-hydroxy derivative.

R W Baldwin
M G Romeril
Research01 Sept 1969
British Journal of Cancer

Volume: 23, P: 536-546
TP53 gene mutations and protein accumulation in primary vaginal carcinomas

H Skomedal
G Kristensen
R Holm
Research01 Jul 1995
British Journal of Cancer

Volume: 72, P: 129-133
Transient reversion of ras oncogene-induced cell transformation by antibodies specific for amino acid 12 of ras protein

J. R. Feramisco
R. Clark
F. McCormick
Research18 Apr 1985
Nature

Volume: 314, P: 639-642
Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation

A vesicle trafficking Rab11 effector switch is important for ciliogenesis. Here, the authors report a ciliopathy-related disorder caused by variants in WDR44, a Rab11 effector. WDR44 variants show higher affinity for Rab11 and can impair ciliogenesis.

Andrea Accogli
Saurabh Shakya
Christopher J. Westlake
ResearchOpen Access08 Jan 2024
Nature Communications

Volume: 15, P: 1-20
A spreading episode at the southern end of the San Andreas fault system

Paul G. Silver
J. N. Valette-Silver
Research09 Apr 1987
Nature

Volume: 326, P: 589-593
Goose lysozyme structure: an evolutionary link between hen and bacteriophage lysozymes?

M. G. Grütter
L. H. Weaver
B. W. Matthews
Research30 Jun 1983
Nature

Volume: 303, P: 828-831

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