Davis et al. report that fear memories can be critically regulated by parvalbumin-expressing interneurons in the basolateral amygdala. Silencing these interneurons following fear memory extinction caused a reemergence of fear expression that was accompanied by increased activation of fear-encoding neurons and fear-associated 3–6 Hz oscillations within a basolateral amygdala–prefrontal cortex circuit.
- Patrick Davis
- Yosif Zaki
- Leon G Reijmers