Nature Search

Longitudinal plasma proteomic signatures of elite and viremic spontaneous HIV controllers

Elite and viremic controllers of HIV can spontaneously regulate viral replication, but some lose this ability over time. In this longitudinal cohort study, 31% of viremic and 3% of elite HIV controllers lost viral control over 17 years. Specific T-cell– related proteins distinguish controller types and predict loss years in advance.

Nadira Vadaq
Albert L. Groenendijk
André J. A. M. van der Ven
ResearchOpen Access22 Jan 2026
Nature Communications

Volume: 17, P: 1-17
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

Carotid intima-media thickness (cIMT) and plaque are associated with subclinical atherosclerosis and coronary heart disease (CHD). Here, the authors identify and prioritize genetic loci for cIMT and plaque by GWAS and colocalization approaches and further demonstrate genetic correlation with CHD and stroke.

Nora Franceschini
Claudia Giambartolomei
Christopher J. O’Donnell
ResearchOpen Access03 Dec 2018
Nature Communications

Volume: 9, P: 1-14
The structure of the flavoenzyme glutathione reductase

G. E. Schulz
R. H. Schirmer
E. F. Pai
Research11 May 1978
Nature

Volume: 273, P: 120-124
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Keeping emissions scenarios current

Climate change research and policy rely on emissions scenarios to project future warming and its impacts. Now, a study highlights both progress and challenges to keeping key socioeconomic scenario assumptions up to date for the IPCC.

Matthew G. Burgess
Ashley Dancer
News & Views03 Jan 2025
Nature Climate Change

Volume: 15, P: 131-132
Complete DNA sequence of yeast chromosome XI

B. Dujon
D. Alexandraki
H. W. Mewes
Research02 Jun 1994
Nature

Volume: 369, P: 371-378
The expression of MDM2/CDK4 gene product in the differential diagnosis of well differentiated liposarcoma and large deep-seated lipoma

S Pilotti
G Della Torre
M A Pierotti
ResearchOpen Access07 Mar 2000
British Journal of Cancer

Volume: 82, P: 1271-1275
DDT and PCB in Marine Animals from Swedish Waters

S. JENSEN
A. G. JOHNELS
G. OTTERLIND
Research18 Oct 1969
Nature

Volume: 224, P: 247-250
Genetic and molecular landscape of comorbidities in people living with HIV

An integrated dataset combining genetics, epigenomics, transcriptomics, proteomics and metabolomics from 1,342 people living with HIV illuminates molecular pathways driving immune responses and comorbidities in this population.

Javier Botey-Bataller
Nienke van Unen
Yang Li
ResearchOpen Access20 Aug 2025
Nature Medicine

Volume: 31, P: 3350-3359
Personalized CRISPR knock-in cytokine gene therapy to remodel the tumor microenvironment and enhance CAR T cell therapy in solid tumors

Solid tumors often resist immunotherapy due to an immunosuppressive tumor microenvironment. Here, the authors develop CancerPAM, a multiomics CRISPR pipeline that enables tumor-specific cytokine expression to boost immune infiltration and CAR T cell efficacy in neuroblastoma.

Michael Launspach
Julia Macos
Annette Künkele
ResearchOpen Access09 Dec 2025
Nature Communications

Volume: 16, P: 1-18
Gradient descent in materia through homodyne gradient extraction

Training deep neural networks by backpropagation consumes significant energy in digital hardware. Boon and Cassola et al. show that homodyne detection can be used to extract gradients directly in a physical device, enabling efficient gradient descent and offering a scalable route to material-based learning.

Marcus N. Boon
Lorenzo Cassola
Wilfred G. van der Wiel
ResearchOpen Access21 Nov 2025
Nature Communications

Volume: 16, P: 1-10
Immunoperoxidase visualisation of microtubules and microtubular proteins

J. DE MEY
J. HOEBEKE
M. JONIAU
Research18 Nov 1976
Nature

Volume: 264, P: 273-275
Effect of Ferric Dimethyldithiocarbamate on the Rooting of Cuttings of Hevea brasiliensis

G. H. TINLEY
Research16 Sept 1961
Nature

Volume: 191, P: 1217-1218
The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy

In three mouse models of breast cancer, we show reduced responses to neoadjuvant chemotherapy when treatment is initiated during the dioestrus stage, when compared with initiation during the oestrus stage.

Laura Bornes
Lennart J. van Winden
Jacco van Rheenen
ResearchOpen Access04 Dec 2024
Nature

Volume: 637, P: 195-204
A first-order Mott transition in Li_xCoO₂

C. A. Marianetti
G. Kotliar
G. Ceder
Research22 Aug 2004
Nature Materials

Volume: 3, P: 627-631
Precursor forms of penicillin-binding proteins 5 and 6 of E. coli cytoplasmic membrane

Julie M. Pratt
I. Barry Holland
Brian G. Spratt
Research24 Sept 1981
Nature

Volume: 293, P: 307-309
Doppler Temperature of the Solar Corona

J. G. HIRSCHBERG
A. WOUTERS
M. READ
Research20 Jun 1970
Nature

Volume: 226, P: 1142-1143
The use of RAPD markers for the identification of Sitka spruce (Picea sitchensis) clones

Wilhelmina T G Van de Ven
Ronnie J McNicol
Research01 Aug 1995
Heredity

Volume: 75, P: 126-132
Solubilisation of atropine-binding material from brain

S. CARSON
S. GODWIN
G. KATO
Research10 Mar 1977
Nature

Volume: 266, P: 176-178
Physical map of a 1.5 Mb region on 12p11.2 harbouring a synpolydactyly associated chromosomal breakpoint

Ph Debeer
EFPM Schoenmakers
WJM Van de Ven
Research31 Jul 2000
European Journal of Human Genetics

Volume: 8, P: 561-570
Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats

P. Hilbert
K. Lindpaintner
G. M. Lathrop
Research10 Oct 1991
Nature

Volume: 353, P: 521-529
The solution structure of an HMG-I(Y)–DNA complex defines a new architectural minor groove binding motif

Jeffrey R. Huth
Carole A. Bewley
G. Marius Clore
Research01 Aug 1997
Nature Structural Biology

Volume: 4, P: 657-665
Restriction fragment length polymorphisms as genetic markers in Vicia

M van de Ven
W Powell
R Waugh
Research01 Dec 1990
Heredity

Volume: 65, P: 329-342
Yttrium and lanthanum hydride films with switchable optical properties

J. N. Huiberts
R. Griessen
N. J. Koeman
Research21 Mar 1996
Nature

Volume: 380, P: 231-234
Molecular cloning of a new transforming gene from a chemically transformed human cell line

Colin S. Cooper
Morag Park
George F. Vande Woude
Research06 Sept 1984
Nature

Volume: 311, P: 29-33
Clostridium botulinum can grow and form toxin at pH values lower than 4.6

G. J. M. Raatjes
J. P. P. M. Smelt
Research01 Oct 1979
Nature

Volume: 281, P: 398-399
Author Correction: Classification with a disordered dopant atom network in silicon

Tao Chen
Jeroen van Gelder
Wilfred G. van der Wiel
Amendments and Corrections11 Mar 2025
Nature

Volume: 639, P: E22
A gene deleted in Kallmann's syndrome shares homology with neural cell adhesion and axonal path-finding molecules

Brunella Franco
Silvana Guioli
Andrea Ballabio
Research10 Oct 1991
Nature

Volume: 353, P: 529-536
Calving fluxes and basal melt rates of Antarctic ice shelves

An estimate of the mass balance components for all ice shelves in Antarctica indicates that about half of the ice-sheet surface mass gain is lost through oceanic erosion before reaching the ice front, and that the loss due to iceberg calving is about 34 per cent less than previously thought.

M. A. Depoorter
J. L. Bamber
G. Moholdt
Research15 Sept 2013
Nature

Volume: 502, P: 89-92
Urban living in healthy Tanzanians is associated with an inflammatory status driven by dietary and metabolic changes

Rapid urbanization can be associated with adverse health implications. de Mast and colleagues compare urban and rural Tanzanian populations using multi-omics and observe that urbanization is associated with an elevated but reversible inflammatory state.

Godfrey S. Temba
Vesla Kullaya
Quirijn de Mast
Research11 Feb 2021
Nature Immunology

Volume: 22, P: 287-300
Physical Sciences: Circular Polarization of Twilight

J. R. P. ANGEL
R. ILLING
P. G. MARTIN
Research18 Aug 1972
Nature

Volume: 238, P: 389-390
Immune and metabolic effects of African heritage diets versus Western diets in men: a randomized controlled trial

A randomized crossover trial showed that transition to a Western diet resulted in pro-inflammatory changes, whereas transition to an African heritage diet rich in fruits and vegetables, legumes and fermented products led to opposite effects.

Godfrey S. Temba
Tal Pecht
Quirijn de Mast
ResearchOpen Access03 Apr 2025
Nature Medicine

Volume: 31, P: 1698-1711
Effect of Indomethacin on Cerebral Oxidized Cytochrome Oxidase in Preterm Infants

D C Mccormick
A D Edwards
E O R Reynolds
Research01 Jun 1993
Pediatric Research

Volume: 33, P: 603-608
Synthesis of Optically Active γ- and δ-Lactones by Microbiological Reduction

G. TUYNENBURG MUYS
B. VAN DER VEN
A. P. DE JONGE
Research09 Jun 1962
Nature

Volume: 194, P: 995-996
Liposome-mediated transformation of streptomycetes by chromosomal DNA

John F. Makins
G. Holt
Research22 Oct 1981
Nature

Volume: 293, P: 671-673
Granulocyte and Granulocyte-Macrophage Colony-Stimulating Factors in Cord and Maternal Serum at Delivery

K E M Bailie
A E Irvine
B G McClure
Research01 Feb 1994
Pediatric Research

Volume: 35, P: 164-168
Polymersomes with splenic avidity target red pulp myeloid cells for cancer immunotherapy

Delivering immunomodulatory compounds to myeloid cells can activate innate immunity for cancer immunotherapy. Here the authors design a polymersome-based nanocarrier for delivering β-glucan to red pulp myeloid cells in the spleen and show that their strategy achieves tumour growth reduction in a melanoma model.

Annelies C. Wauters
Jari F. Scheerstra
Jan C. M. van Hest
ResearchOpen Access31 Jul 2024
Nature Nanotechnology

Volume: 19, P: 1735-1744
Divergent WNT signaling and drug sensitivity profiles within hepatoblastoma tumors and organoids

WNT-activating mutations in CTNNB1 are common in hepatoblastoma, but downstream molecular phenotypes are heterogenous. Using multiomic approaches, the authors identify distinct subgroups of hepatoblastoma cells based on WNT-signaling patterns and create a biobank of patient-derived hepatoblastoma organoids representing these subtypes.

Thomas A. Kluiver
Yuyan Lu
Weng Chuan Peng
ResearchOpen Access20 Nov 2024
Nature Communications

Volume: 15, P: 1-17
Generation of Seismic Anisotropy in the Upper Mantle along the Mid-Oceanic Ridges

T. J. G. FRANCIS
Research11 Jan 1969
Nature

Volume: 221, P: 162-165
onc sequences (v-fes) of Snyder–Theilen feline sarcoma virus are derived from noncontiguous regions of a cat cellular gene (c-fes)

G. Franchini
J. Even
F. Wong-Staal
Research12 Mar 1981
Nature

Volume: 290, P: 154-157
Development of virus non-producer lymphosarcomas in pet cats exposed to FeLV

W. D. Hardy Jr
A. J. McClelland
M. Essex
Research06 Nov 1980
Nature

Volume: 288, P: 90-92
Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse

David A. Williams
Ihor R. Lemischka
Richard C. Mulligan
Research09 Aug 1984
Nature

Volume: 310, P: 476-480
Wet and dry tropical forests show opposite successional pathways in wood density but converge over time

Neotropical tree community composition shows opposing successional pathways for wet and dry forests, but as vegetation cover increases over time, trends converge. Selecting species that have similar wood density to early successional communities could improve reforestation prospects.

Lourens Poorter
Danaë M. A. Rozendaal
Mark Westoby
Research22 Apr 2019
Nature Ecology & Evolution

Volume: 3, P: 928-934
Chromosome rearrangements in synovial chondromatous lesions

F Mertens
K Jonsson
N Mandahl
Research01 Jul 1996
British Journal of Cancer

Volume: 74, P: 251-254
Erratum: Mutations in human TBX5 cause limb and cardiac malformation in Holt-Oram syndrome

Craig T. Basson
David R. Bachinsky
Christine E. Seidman
Amendments and Corrections01 Apr 1997
Nature Genetics

Volume: 15, P: 411
Fine-tuning levels of filamins a and b as a specific mechanism sustaining Th2 lymphocyte functions

Filamin proteins are degraded by ASB2α E3 ubiquitin ligase and may affect T cell function. Here the authors show that increased levels of Filamin A and Filamin B in Th2 cells reduces allergic inflammation in mouse models through reduced Th2 cell recruitment into inflamed lungs.

Kilian Maire
Léa Chamy
Isabelle Lamsoul
ResearchOpen Access05 Dec 2024
Nature Communications

Volume: 15, P: 1-17
Reducing the cost of capital to finance the energy transition in developing countries

Fair finance in the energy sector is modelled in five climate–energy–economy models. The results show that convergence costs of capital could improve energy availability, affordability and sustainability in developing countries, thereby increasing the international equity of the energy transition.

M. Calcaterra
L. Aleluia Reis
M. Tavoni
ResearchOpen Access27 Sept 2024
Nature Energy

Volume: 9, P: 1241-1251
Outcomes of controlled human malaria infection after BCG vaccination

Immune activation induces long-term alterations of setpoints, impacting responses to subsequent unrelated stimuli. Here the authors show that volunteers vaccinated with BCG respond to controlled human malaria infection with increased clinical symptoms and an inverse correlation between immune activation markers and parasitemia.

Jona Walk
L. Charlotte J. de Bree
Robert W. Sauerwein
ResearchOpen Access20 Feb 2019
Nature Communications

Volume: 10, P: 1-8
SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8⁺ T cells

Thomas and colleagues describe how multiple SARS-CoV-2 antigen exposures, including mRNA vaccine boosters, primary infection and breakthrough infection, shape T cell immunity.

Anastasia A. Minervina
Mikhail V. Pogorelyy
Paul G. Thomas
Research05 Apr 2022
Nature Immunology

Volume: 23, P: 781-790
A conserved HH-Gli1-Mycn network regulates heart regeneration from newt to human

Due to the limited proliferation capacity of adult mammalian cardiomyocytes, the human heart has negligible regenerative capacity after injury. Here the authors show that a Hedgehog-Gli1-Mycn signaling cascade regulates cardiomyocyte proliferation and cardiac regeneration from amphibians to mammals.

Bhairab N. Singh
Naoko Koyano-Nakagawa
Daniel J. Garry
ResearchOpen Access12 Oct 2018
Nature Communications

Volume: 9, P: 1-18

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