Patients with myelodysplastic syndromes (MDS) have limited therapeutic options. Here the authors show that functionally impaired NK cells contribute to immune escape of pre-malignant clones in early stage MDS and that NK adoptive cell therapy can be considered to prevent or delay the development of MDS.
- Juan Jose Rodriguez-Sevilla
- Irene Ganan-Gomez
- Simona Colla
