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Showing 1–4 of 4 results
Advanced filters: Author: Gayatri S. Ganesan Clear advanced filters

  • The tumor suppressor RAD51C is mutated in ovarian cancers. Through variant analysis the authors identify a mutation cluster in the RAD51C Walker B region important for the repair of DNA double-strand breaks and replicative damage. By identifying Walker B separation-of-function alleles, they show that these activities can be uncoupled.

    • Hayley L. Rein
    • Yashpal Rawal
    • Kara A. Bernstein
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • The rich ethnolinguistic and sociocultural differences that exist in India offers a unique opportunity to study human diversity. With the whole genomes of 10,000 healthy and unrelated Indians from 83 populations, the GenomeIndia project captures the genetic diversity of one of the highly underrepresented populations in the global genomics landscape.

    • Chandrika Bhattacharyya
    • Krithika Subramanian
    • Bratati Kahali
    Comments & Opinion
    Nature Genetics
    Volume: 57, P: 767-773