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Perinatal SSRI exposure impacts innate fear circuit activation and behavior in mice and humans

Long-term effects of fetal SSRI exposure—commonly prescribed to pregnant mothers who suffer from depression and anxiety—are unknown. Here, authors finds increased fear-related behaviors and matching brain circuit activation in both mice and humans.

Giulia Zanni
Milenna T. van Dijk
Jay A. Gingrich
ResearchOpen Access06 May 2025
Nature Communications

Volume: 16, P: 1-13
Irradiation-induced changes in neural progenitor cells are reversed by lithium: Immature newborn dentate granule neurons display dendritic processes that are either tangential or parallel to the granule cell layer of the dentate gyrus of the hippocampus

Giulia Zanni
Shinobu Goto
Klas Blomgren
Research19 Jan 2021
Molecular Psychiatry

Volume: 26, P: 1-2
Lithium treatment reverses irradiation-induced changes in rodent neural progenitors and rescues cognition

Giulia Zanni
Shinobu Goto
Klas Blomgren
ResearchOpen Access14 Nov 2019
Molecular Psychiatry

Volume: 26, P: 322-340
A deeper understanding of system interactions can explain contradictory field results on pesticide impact on honey bees

Pesticide impact on honey bees under field conditions remains elusive. Here, the authors combine a systems biology approach and laboratory experiments to show that the immune suppressive effect of the pathogen deformed wing virus can be responsible for the disparity amongst honey bee experiments.

Dimitri Breda
Davide Frizzera
Francesco Nazzi
ResearchOpen Access29 Sept 2022
Nature Communications

Volume: 13, P: 1-13
Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging

Giulia Zanni
Wojciech Michno
Jörg Hanrieder
ResearchOpen Access18 Jan 2017
Scientific Reports

Volume: 7, P: 1-12
Dopamine transporter blockade during adolescence increases adult dopamine function, impulsivity, and aggression

Deepika Suri
Giulia Zanni
Mark S. Ansorge
ResearchOpen Access02 Aug 2023
Molecular Psychiatry

Volume: 28, P: 3512-3523

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Perinatal SSRI exposure impacts innate fear circuit activation and behavior in mice and humans

Irradiation-induced changes in neural progenitor cells are reversed by lithium: Immature newborn dentate granule neurons display dendritic processes that are either tangential or parallel to the granule cell layer of the dentate gyrus of the hippocampus

Lithium treatment reverses irradiation-induced changes in rodent neural progenitors and rescues cognition

A deeper understanding of system interactions can explain contradictory field results on pesticide impact on honey bees

Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging

Dopamine transporter blockade during adolescence increases adult dopamine function, impulsivity, and aggression

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