Nature Search

Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin

Rifaximin use, particularly in patients with liver cirrhosis, may be compromising the clinical use of daptomycin.

Adrianna M. Turner
Lucy Li
Glen P. Carter
ResearchOpen Access23 Oct 2024
Nature

Volume: 635, P: 969-977
Rapid response of treeline vegetation and lakes to past climate warming

Glen M. MacDonald
Tom W. D. Edwards
John P. Smol
Research01 Jan 1993
Nature

Volume: 361, P: 243-246
Body composition changes in female bodybuilders during preparation for competition

GE van der Ploeg
AG Brooks
BE Chatterton
Research02 May 2001
European Journal of Clinical Nutrition

Volume: 55, P: 268-277
Inter-species gene flow drives ongoing evolution of Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis

Streptococcus dysgalactiae subsp. equisimilis (SDSE) is an emerging cause of human infection closely related to Streptococcus pyogenes. Here the authors investigate the degree of genomic similarity between the two species and assess implications for development of vaccines.

Ouli Xie
Jacqueline M. Morris
Mark R. Davies
ResearchOpen Access13 Mar 2024
Nature Communications

Volume: 15, P: 1-14
Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair

Here the authors describe a functional screening platform in human stem cells to identify and optimize protein-based gene editing additives that increase homologous directed recombination and have potential to improve gene therapy workflows.

Juan A. Perez-Bermejo
Oghene Efagene
Kristen L. Seim
ResearchOpen Access23 Mar 2024
Nature Communications

Volume: 15, P: 1-16
Oral nanotherapeutic formulation of insulin with reduced episodes of hypoglycaemia

Insulin injections are not ideal and have an increased risk of hypoglycaemia. A preferable oral formulation based on silver sulfide quantum dots coated with a chitosan/glucose polymer is discussed, which has controlled insulin release and reduced risk of hypoglycaemia, and demonstrates applications in rodent and non-human primate models.

Nicholas J. Hunt
Glen P. Lockwood
Victoria C. Cogger
ResearchOpen Access02 Jan 2024
Nature Nanotechnology

Volume: 19, P: 534-544
A physical map of the mouse genome

Simon G. Gregory
Mandeep Sekhon
David R. Bentley
Research04 Aug 2002
Nature

Volume: 418, P: 743-750
Correction: Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome

Kerstin Howe
Matthew D. Clark
Derek L. Stemple
Amendments and Corrections11 Dec 2013
Nature

Volume: 505, P: 248
Bisphenol S rapidly depresses heart function through estrogen receptor-β and decreases phospholamban phosphorylation in a sex-dependent manner

Melissa Ferguson
Ilka Lorenzen-Schmidt
W. Glen Pyle
ResearchOpen Access04 Nov 2019
Scientific Reports

Volume: 9, P: 1-12
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

Primary biliary cirrhosis is an autoimmune liver disease with poor therapeutic options. Here Cordell et al. a perform meta-analysis of European genome-wide association studies identifying six novel risk loci and a number of potential therapeutic pathways.

Heather J. Cordell
Younghun Han
Katherine A. Siminovitch
ResearchOpen Access22 Sept 2015
Nature Communications

Volume: 6, P: 1-11
Australian climate–carbon cycle feedback reduced by soil black carbon

Global warming is likely to increase soil organic carbon decomposition, and thus CO₂ release to the atmosphere, creating a positive feedback cycle. Inclusion of realistic estimates of soil black carbon in a climate model results in a decrease in soil CO₂ emission in Australia by up to 24.4% following a 3 ^∘C warming over 100 years, suggesting that black carbon reduces the strength of this feedback.

Johannes Lehmann
Jan Skjemstad
Evelyn Krull
Research16 Nov 2008
Nature Geoscience

Volume: 1, P: 832-835
The zebrafish reference genome sequence and its relationship to the human genome

A high-quality sequence assembly of the zebrafish genome reveals the largest gene set of any vertebrate and provides information on key genomic features, and comparison to the human reference genome shows that approximately 70% of human protein-coding genes have at least one clear zebrafish orthologue.

Kerstin Howe
Matthew D. Clark
Derek L. Stemple
ResearchOpen Access17 Apr 2013
Nature

Volume: 496, P: 498-503
Toxin B is essential for virulence of Clostridium difficile

Clostridium difficile, the cause of antibiotic-induced infection in hospitals, possesses two toxins, A and B, the former of which was believed to be the major C. difficile virulence factor. Using an animal model and C. difficile mutants, evidence is now presented that toxin B, and not toxin A, is essential for infection.

Dena Lyras
Jennifer R. O’Connor
Julian I. Rood
Research01 Mar 2009
Nature

Volume: 458, P: 1176-1179
Deciphering the impact of genomic variation on function

The Impact of Genomic Variation on Function Consortium is combining single-cell mapping, genomic perturbations and predictive modelling to investigate relationships between human genomic variation, genome function and phenotypes and will provide an open resource to the community.

Jesse M. Engreitz
Heather A. Lawson
Ella K. Samer
Reviews04 Sept 2024
Nature

Volume: 633, P: 47-57
Modulatory Effects of Modafinil on Neural Circuits Regulating Emotion and Cognition

Roberta Rasetti
Venkata S Mattay
Daniel R Weinberger
Research16 Jun 2010
Neuropsychopharmacology

Volume: 35, P: 2101-2109
Systemic inflammatory response predicts outcome in patients undergoing resection for ductal adenocarcinoma head of pancreas

N B Jamieson
P Glen
C W Imrie
ResearchOpen Access14 Dec 2004
British Journal of Cancer

Volume: 92, P: 21-23
High spatial resolution global ocean metagenomes from Bio-GO-SHIP repeat hydrography transects

Alyse A. Larkin
Catherine A. Garcia
Adam C. Martiny
ResearchOpen Access16 Apr 2021
Scientific Data

Volume: 8, P: 1-6
Emergence and clonal expansion of a qacA-harbouring sequence type 45 lineage of methicillin-resistant Staphylococcus aureus

A study underscores the emergence of a qacA-harbouring multidrug-resistant sequence type 45 methicillin-resistant Staphylococcus aureus lineage, highlighting the potential impact of biocide tolerance on its recent clonal spread in Australia and Asia.

Yi Nong
Eike Steinig
Deborah A. Williamson
ResearchOpen Access21 Mar 2024
Communications Biology

Volume: 7, P: 1-10
Multi-modality machine learning predicting Parkinson’s disease

Mary B. Makarious
Hampton L. Leonard
Mike A. Nalls
ResearchOpen Access01 Apr 2022
npj Parkinson's Disease

Volume: 8, P: 1-13
Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder

Tim B. Bigdeli
Peter B. Barr
Philip D. Harvey
Research15 Mar 2024
Molecular Psychiatry

Volume: 29, P: 2399-2407
Initial sequencing and analysis of the human genome

Eric S. Lander
Lauren M. Linton
Michael J. Morgan
articles01 Feb 2001
Nature

Volume: 409, P: 860-921

Search

Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin

Rapid response of treeline vegetation and lakes to past climate warming

Body composition changes in female bodybuilders during preparation for competition

Inter-species gene flow drives ongoing evolution of Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis

Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair

Oral nanotherapeutic formulation of insulin with reduced episodes of hypoglycaemia

A physical map of the mouse genome

Correction: Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome

Bisphenol S rapidly depresses heart function through estrogen receptor-β and decreases phospholamban phosphorylation in a sex-dependent manner

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

Australian climate–carbon cycle feedback reduced by soil black carbon

The zebrafish reference genome sequence and its relationship to the human genome

Toxin B is essential for virulence of Clostridium difficile

Deciphering the impact of genomic variation on function

Modulatory Effects of Modafinil on Neural Circuits Regulating Emotion and Cognition

Systemic inflammatory response predicts outcome in patients undergoing resection for ductal adenocarcinoma head of pancreas

High spatial resolution global ocean metagenomes from Bio-GO-SHIP repeat hydrography transects

Emergence and clonal expansion of a qacA-harbouring sequence type 45 lineage of methicillin-resistant Staphylococcus aureus

Multi-modality machine learning predicting Parkinson’s disease

Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder

Initial sequencing and analysis of the human genome

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