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Showing 1–3 of 3 results
Advanced filters: Author: Greta Meregalli Clear advanced filters

  • Smoldering multiple myeloma (SMM) may develop into life- threatening MM, with gut microbiota and Th17 possibly contributing to this progression via unknown mechanisms. Here the authors use a mouse SMM model, VkMYC mice, to show that treatments with butyrate or the commensal, Prevotella melaninogenica, suppress Th17 and cancer progression.

    • Laura Lucia Cogrossi
    • Anna Policastro
    • Matteo Bellone
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Tumor-associated macrophages are pivotal in control over solid tumors. Here the authors show that these macrophages express chemosensors that detect lipid variants in the tumor microenvironment that can regulate the function of these cells.

    • Giulia Marelli
    • Nicolò Morina
    • Diletta Di Mitri
    ResearchOpen Access
    Nature Immunology
    Volume: 26, P: 1182-1197

  • NK cells play an important role in anti-tumour immunity, however, the immune-hostile microenvironment often impairs their function. Here authors show that cancers disable autophagy in NK cells, and by restoring this process, intra-tumour NK cells could be re-invigorated.

    • Federica Portale
    • Roberta Carriero
    • Diletta Di Mitri
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-21