C elegans is a model organism for life span research, and mitochondrial translation has been identified as a key process affecting longevity. Here authors show that the previously identified proteostasis is not the only mechanism that defines longevity induced by mitochondrial translation inhibition, but also C32E8.9-induced lipid remodelling and immune responses.
- Iman Man Hu
- Marte Molenaars
- Riekelt H. Houtkooper
