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Showing 1–8 of 8 results
Advanced filters: Author: Guillermo E. Umpierrez Clear advanced filters
  • Although diabetic ketoacidosis is considered a key clinical feature of type 1 diabetes mellitus, this phenomenon has become increasingly common in patients with type 2 diabetes mellitus. The authors of this Viewpoint examine the diagnostic criteria, precipitating causes, and pathogenesis of diabetic ketoacidosis associated with type 2 diabetes mellitus.

    • Stephen N Davis
    • Guillermo E Umpierrez
    Reviews
    Nature Clinical Practice Endocrinology & Metabolism
    Volume: 3, P: 730-731
  • Patients with sickle-cell disease can suffer both from the direct consequences of the disease and from iron overload due to repeated transfusions. As described in this article, a wide range of endocrine, metabolic and nutritional abnormalities are found in this patient group, and often occur before iron overload is evident.

    • Dawn Smiley
    • Samuel Dagogo-Jack
    • Guillermo Umpierrez
    Reviews
    Nature Clinical Practice Endocrinology & Metabolism
    Volume: 4, P: 102-109
  • Inpatient hyperglycaemia is found in the settings of known diabetes mellitus, previously undiagnosed diabetes mellitus and stress hyperglycaemia, and is associated with poor outcomes. Current approaches to managing inpatient hyperglycaemia and diabetes mellitus are outlined in this Review.

    • Thaer Idrees
    • Iris Castro-Revoredo
    • Guillermo E. Umpierrez
    Reviews
    Nature Reviews Endocrinology
    P: 1-12
  • Diabetic ketoacidosis is a worrying complication associated with the use of sodium/glucose cotransporter 2 (SGLT2) inhibitors in patients with type 1 diabetes mellitus (T1DM) or T2DM. A recent analysis of data in the FDA Adverse Event Reporting System by Fadini and colleagues adds to this concern.

    • Guillermo E. Umpierrez
    News & Views
    Nature Reviews Endocrinology
    Volume: 13, P: 441-442
  • This Primer by Umpierrez and colleagues reviews the epidemiology, pathophysiology, diagnosis and management of diabetic ketoacidosis, the most common acute hyperglycaemic emergency in people with diabetes mellitus. Additionally, the authors also discuss different strategies that can be implemented to prevent recurrent diabetic ketoacidosis episodes.

    • Ketan K. Dhatariya
    • Nicole S. Glaser
    • Guillermo E. Umpierrez
    Reviews
    Nature Reviews Disease Primers
    Volume: 6, P: 1-20
  • In a retrospective cohort study examining the comparative effectiveness of diabetes drugs in adults at moderate risk for cardiovascular disease, GLP-1 receptor agonists and SGLT2 inhibitors reduced the risk of cardiovascular events compared to DPP4 inhibitors, whereas sulfonylureas increased the risk.

    • Rozalina G. McCoy
    • Jeph Herrin
    • Eric C. Polley
    Research
    Nature Cardiovascular Research
    Volume: 3, P: 431-440