It is generally assumed that CO2 production is coupled to ferredoxin reduction during anaerobic alkane oxidation in archaea. Here, Lemaire et al. use biochemical and structural techniques to study native enzymes purified from an ethane-oxidising enrichment culture, showing that the enzymes deliver electrons to the F420 cofactor rather than to ferredoxin.
- Olivier N. Lemaire
- Gunter Wegener
- Tristan Wagner
