Syedain et al. evaluate growth of biologically-engineered grafts grown from donor ovine fibroblasts in a sacrificial fibrin gel implanted into the left pulmonary branch of 3-month old lambs. The grafts exhibit extensive site-appropriate recellularization and increase in diameter and length until the lambs reach adulthood.
- Zeeshan H. Syedain
- Matthew Lahti
- Robert T. Tranquillo