Understanding of the sequelae of cerebral microvascular injury has been hampered by a lack of animal models to enable precise localization of injury. In this issue, Nishimura et al. describe a stroke model that couples two-photon laser-scanning mapping of the cerebral cortex with femtosecond laser technology to produce three distinct microvascular injuries characterized by hemorrhage, vessel leakage or vessel occlusion.
- Robert Flaumenhaft
- Eng H Lo
