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Mazdutide versus placebo in Chinese adults with type 2 diabetes

The dual GLP-1 and glucagon receptor co-agonist mazdutide is a promising therapeutic option for type 2 diabetes (T2D) treatment, providing clinically meaningful glycaemic control and weight reduction in Chinese adults with T2D.

Dalong Zhu
Jiajun Zhao
Lei Qian
Research17 Dec 2025
Nature

P: 1-7
Multi-center multi-omics integration predicts individualized prognosis in medullary thyroid carcinoma

Medullary thyroid carcinoma (MTC) is a rare and aggressive neuroendocrine tumor with limited risk stratification. Here, the authors perform multi-omic analysis of MTC samples from 452 patients across 10 Chinese clinical centers, identify molecular subtypes and develop a prediction model.

Yan Zhou
Yingrui Wang
Tiannan Guo
ResearchOpen Access14 Jan 2026
Nature Communications

Volume: 17, P: 1-19
Mazdutide versus dulaglutide in Chinese adults with type 2 diabetes

The results of a clinical trial of mazdutide, a dual glucagon and GLP-1 receptor agonist, in the context of type 2 diabetes show that it could hold promise as an add-on therapy to conventional oral anti-diabetic drugs.

Lixin Guo
Bo Zhang
Wenying Yang
Research17 Dec 2025
Nature

P: 1-8
ZnO nanoparticles act as supportive therapy in DSS-induced ulcerative colitis in mice by maintaining gut homeostasis and activating Nrf2 signaling

Jinquan Li
Hanqing Chen
Weiyue Feng
ResearchOpen Access24 Feb 2017
Scientific Reports

Volume: 7, P: 1-11
Dorzagliatin in drug-naïve patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 3 trial

The SEED study is a phase 3 clinical trial demonstrating a beneficial effect on glycemic control of dorzagliatin, a glucokinase activator, in drug-naive patients with newly diagnosed type 2 diabetes.

Dalong Zhu
Xiaoying Li
Li Chen
Research12 May 2022
Nature Medicine

Volume: 28, P: 965-973
Controlling Mie scattering response to refractive index variations via light field manipulation

Jianzhi Zeng
Hanqing Cai
Haifeng Hu
ResearchOpen Access04 Apr 2025
Scientific Reports

Volume: 15, P: 1-9
The novel circCLK3/miR-320a/FoxM1 axis promotes cervical cancer progression

Hanqing Hong
Hai Zhu
Hongyu Li
ResearchOpen Access12 Dec 2019
Cell Death & Disease

Volume: 10, P: 1-19
Mast Cells Participate in Corneal Development in Mice

Jun Liu
Ting Fu
Zhijie Li
ResearchOpen Access02 Dec 2015
Scientific Reports

Volume: 5, P: 1-14
Insulin Restores an Altered Corneal Epithelium Circadian Rhythm in Mice with Streptozotocin-induced Type 1 Diabetes

Fang Song
Yunxia Xue
Zhijie Li
ResearchOpen Access09 Sept 2016
Scientific Reports

Volume: 6, P: 1-9

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