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Showing 1–9 of 9 results
Advanced filters: Author: Haoyue Tan Clear advanced filters

  • Clinical approaches for cancer therapy face several interrelated challenges. Here, Xue et al. presented an integrated wearable flexible ultrasound microneedle patch that serves as a portable platform for convenient and minimally invasive cancer therapy.

    • Haoyue Xue
    • Jing Jin
    • Jiagang Wu
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-20

  • C–H activation in long-chain organic molecules remains largely unexplored. Here, the authors report light-driven C–H activation mediated by 2D TMDCs and the resultant synthesis of luminescent carbon dots.

    • Jingang Li
    • Di Zhang
    • Yuebing Zheng
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-7

  • Authors introduce an unsupervised framework for automatic modulation recognition. By using multi-domain signal representation and contrastive learning, it extracts high-quality features from unlabelled data, outperforming existing methods and reducing the need for labelled samples in wireless communications.

    • Yu Li
    • Xiaoran Shi
    • Feng Zhou
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • Cochlear implantation requires highly accurate multi-axis force sensing in the constrained operating environment. Here, the authors present a multi-axis pneumatic forceps capable of independent rotations and translations, enhancing operation precision and stability during robotic microsurgery.

    • Hongyan Gao
    • Huanghua Liu
    • Anzhu Gao
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • The functional relevance of lysine crotonylation in cancer remains to be further explored. Here, the authors show that hypoxia-induced downregulation of PGK1 lysine crotonylation promotes glycolysis and suppresses mitochondrial pyruvate metabolism, contributing to breast cancer progression.

    • Zihao Guo
    • Yang Zhang
    • Chuanzhen Yang
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • Third-generation EGFR tyrosine-kinase inhibitors (TKIs) are the standard-of-care first-line treatment for patients with advanced-stage EGFR-mutant NSCLC and their efficacy is being investigated in early stage and locally advanced disease. The authors of this Review describe the current first-line treatment options for EGFR-mutant NSCLC, discuss mechanisms of acquired resistance to third-generation EGFR TKIs and new promising treatment strategies, such as bispecific antibodies, next-generation TKIs, antibody–drug conjugates, immunotherapy approaches and targeted protein degraders.

    • Fei Zhou
    • Haoyue Guo
    • Caicun Zhou
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 22, P: 95-116

  • In an inter-laboratory study, the authors compare the accuracy and performance of three optical density calibration protocols (colloidal silica, serial dilution of silica microspheres, and colony-forming unit (CFU) assay). They demonstrate that serial dilution of silica microspheres is the best of these tested protocols, allowing precise and robust calibration that is easily assessed for quality control and can also evaluate the effective linear range of an instrument.

    • Jacob Beal
    • Natalie G. Farny
    • Jiajie Zhou
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-29