Nature Search

The source of dietary fat influences anti-tumour immunity in obese mice

This study shows that animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based high-fat diets do not.

Britta Kunkemoeller
Hannah Prendeville
Lydia Lynch
ResearchOpen Access25 Jul 2025
Nature Metabolism

Volume: 7, P: 1630-1645
Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity

The L protein of segmented, negative strand RNA viruses contains the RNA-dependent RNA polymerase essential for virus amplification. Here, the authors report cryoEM structures of the Lassa virus L protein in active, RNA-bound states, and provide mechanistic insights.

Tomas Kouba
Dominik Vogel
Stephen Cusack
ResearchOpen Access02 Dec 2021
Nature Communications

Volume: 12, P: 1-18
Thresholds for adding degraded tropical forest to the conservation estate

An analysis of the impact of logging intensity on biodiversity in tropical forests in Sabah, Malaysia, identifies a threshold of tree biomass removal below which logged forests still have conservation value.

Robert M. Ewers
C. David L. Orme
Cristina Banks-Leite
ResearchOpen Access17 Jul 2024
Nature

Volume: 631, P: 808-813
Change in platelet and leukocyte counts and hospital mortality in adults with acute kidney injury receiving continuous renal replacement therapy

Lan N. Bui
Joshua W. Lambert
Javier A. Neyra
ResearchOpen Access29 Sept 2025
Scientific Reports

Volume: 15, P: 1-10
Mapping changes in housing in sub-Saharan Africa from 2000 to 2015

The prevalence of improved housing (with improved drinking water and sanitation, sufficient living area and durable construction) in urban and rural sub-Saharan Africa doubled between 2000 and 2015.

Lucy S. Tusting
Donal Bisanzio
Samir Bhatt
ResearchOpen Access27 Mar 2019
Nature

Volume: 568, P: 391-394
Climate-driven global redistribution of an ocean giant predicts increased threat from shipping

The authors use long-term satellite tracking to project climate-induced shifts in whale shark distributions and understand their potential future risk of ship-strike. Under high-emission scenarios, the movement of sharks to current range-edge habitat is linked to 15,000-fold increased co-occurrence with ships.

Freya C. Womersley
Lara L. Sousa
David W. Sims
ResearchOpen Access07 Oct 2024
Nature Climate Change

Volume: 14, P: 1282-1291
Optimised insert design for improved single-molecule imaging and quantification through CRISPR-Cas9 mediated knock-in

Abdullah O. Khan
Carl W. White
Neil V. Morgan
ResearchOpen Access02 Oct 2019
Scientific Reports

Volume: 9, P: 1-13
Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C

Charlotte Sumner and colleagues report that mutations in the ankyrin repeat region of TRPV4 cause Charcot-Marie-Tooth disease type 2C. Their functional studies indicate that the mutations result in increased channel activity.

Guida Landouré
Anselm A Zdebik
Charlotte J Sumner
Research27 Dec 2009
Nature Genetics

Volume: 42, P: 170-174
Aquaponic growth of basil (Ocimum basilicum) with African catfish (Clarias gariepinus) in standard substrate combined with a Humicacid Fiber-Substrate (HFS)

Ulrich Knaus
Dirk Hyo-Dschung Hübner
Harry W. Palm
ResearchOpen Access31 Jul 2024
Scientific Reports

Volume: 14, P: 1-14
Surfactant protein A promotes western diet-induced hepatic steatosis and fibrosis in mice

Ayobami Dare
Skylar D. King
Shi-You Chen
ResearchOpen Access29 Mar 2024
Scientific Reports

Volume: 14, P: 1-11
Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells

The inflammasome receptor Nlrp9b defends against enteric viruses by interacting with double-stranded viral RNA-bound helicase Dhx9, triggering gasdermin-D-dependent pyroptotic cell death of infected cells and secretion of Il-18.

Shu Zhu
Siyuan Ding
Richard A. Flavell
Research21 Jun 2017
Nature

Volume: 546, P: 667-670
Cellular hormetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity

Brendan Gongol
Traci L. Marin
Salvador Soriano
ResearchOpen Access24 Oct 2017
Scientific Reports

Volume: 7, P: 1-11
Reporting guidelines for human microbiome research: the STORMS checklist

The STORMS tool provides guidance for concise and complete reporting of microbiome studies to facilitate manuscript preparation, peer review, reader comprehension of publications, and comparative analysis of published results.

Chloe Mirzayi
Audrey Renson
Levi Waldron
Reviews17 Nov 2021
Nature Medicine

Volume: 27, P: 1885-1892
Telomerase therapeutics for cancer: challenges and new directions

Telomerase is expressed by cancer cells where it contributes to tumour maintenance, but is absent from most normal cells. Strategies for targeting telomerase therefore provide new opportunities for targeted cancer therapy. Shay and Wright review the current status and future opportunities for telomerase therapeutics.

Jerry W. Shay
Woodring E. Wright
Reviews09 Jun 2006
Nature Reviews Drug Discovery

Volume: 5, P: 577-584
Exploring bacterial cell biology with single-molecule tracking and super-resolution imaging

Here, Gahlmann and Moerner describe single-molecule imaging in live bacterial cells, which has transformed the study of bacterial cell biology. They discuss the insights that have been gained about the bacterial cytoskeleton, nucleoid organization and chromosome segregation and partitioning, as well as transcription and translation.

Andreas Gahlmann
W. E. Moerner
Reviews16 Dec 2013
Nature Reviews Microbiology

Volume: 12, P: 9-22
Lipid modification of GRN163, an N3′ → P5′ thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition

Brittney-Shea Herbert
Ginelle C Gellert
Sergei M Gryaznov
Research23 May 2005
Oncogene

Volume: 24, P: 5262-5268
Growth and fatty acid composition of pikeperch (Sander lucioperca L., 1758) larvae under altered feeding protocol including the copepod Apocyclops panamensis (Marsh, 1913)

Laura Ballesteros-Redondo
Harry W. Palm
Adrian A. Bischoff
ResearchOpen Access10 Nov 2023
Scientific Reports

Volume: 13, P: 1-11
Effects of dietary macronutrients on liver fat content in adults: a systematic review and meta-analysis of randomized controlled trials

Esther Winters-van Eekelen
Inge Verkouter
Renée de Mutsert
Reviews22 Oct 2020
European Journal of Clinical Nutrition

Volume: 75, P: 588-601
The distribution of manta rays in the western North Atlantic Ocean off the eastern United States

Nicholas A. Farmer
Lance P. Garrison
Stephen Kajiura
ResearchOpen Access21 Apr 2022
Scientific Reports

Volume: 12, P: 1-20

Search

The source of dietary fat influences anti-tumour immunity in obese mice

Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity

Thresholds for adding degraded tropical forest to the conservation estate

Change in platelet and leukocyte counts and hospital mortality in adults with acute kidney injury receiving continuous renal replacement therapy

Mapping changes in housing in sub-Saharan Africa from 2000 to 2015

Climate-driven global redistribution of an ocean giant predicts increased threat from shipping

Optimised insert design for improved single-molecule imaging and quantification through CRISPR-Cas9 mediated knock-in

Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C

Aquaponic growth of basil (Ocimum basilicum) with African catfish (Clarias gariepinus) in standard substrate combined with a Humicacid Fiber-Substrate (HFS)

Surfactant protein A promotes western diet-induced hepatic steatosis and fibrosis in mice

Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells

Cellular hormetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity

Reporting guidelines for human microbiome research: the STORMS checklist

Telomerase therapeutics for cancer: challenges and new directions

Exploring bacterial cell biology with single-molecule tracking and super-resolution imaging

Lipid modification of GRN163, an N3′ → P5′ thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition

Growth and fatty acid composition of pikeperch (Sander lucioperca L., 1758) larvae under altered feeding protocol including the copepod Apocyclops panamensis (Marsh, 1913)

Effects of dietary macronutrients on liver fat content in adults: a systematic review and meta-analysis of randomized controlled trials

The distribution of manta rays in the western North Atlantic Ocean off the eastern United States

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