In the postnatal mouse brain, RhoA signalling regulates the saltatory movement of new neurons migrating from the ventricular–subventricular zone to the olfactory bulb. Here the authors show that a RhoA-specific GTPase-activating protein, Gmip, serves as a brake for RhoA-mediated saltatory movement of new neurons during migration.
- Haruko Ota
- Takao Hikita
- Kazunobu Sawamoto