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Advanced filters: Author: Hemashree Bommadevara Clear advanced filters

  • Long-circulating, transfection-competent LNP-mRNA systems are key for effective extrahepatic delivery. Here, authors show that LNPs with high bilayer lipid ratios yield high mRNA encapsulation, prolonged circulation, and enhanced transfection in extrahepatic tissues.

    • Miffy Hok Yan Cheng
    • Yao Zhang
    • Pieter R. Cullis
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-12