Innate immune responses are important in the early phases of infection; for example, natural killer cells are innate lymphocytes that rapidly exhibit cytotoxic activities against virus-infected cells and produce various cytokines. Here, a new type of innate lymphocyte is found in a novel lymphoid structure associated with adipose tissues in the peritoneal cavity. These cells, termed FALC (fat-associated lymphoid cluster) cells, produce TH2 cytokines and support B1 cells.
- Kazuyo Moro
- Taketo Yamada
- Shigeo Koyasu