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Advanced filters: Author: Honoka Tokuhisa Clear advanced filters

  • Branched ubiquitin chains promote substrates degradation. Here, the authors describe an interplay between two ubiquitin ligases, K29-linkage-specific TRIP12 and K48-linkage specific UBR5, which assembles K29/K48 branched ubiquitin chains and facilitates degradation of deubiquitylation-protected substrates.

    • Mai Morita
    • Miyu Takao
    • Fumiaki Ohtake
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17