Nature Search

Observation of nonlinear edge states in an interacting atomic trimer array

We study the impact of interactions on the population distribution in a topological trimer array of ultracold atoms, and observe the formation of nonlinear edge states.

Huiying Du
Hongxing Zhao
Jie Ma
ResearchOpen Access28 Aug 2025
Light: Science & Applications

Volume: 14, P: 1-7
Light-driven transition-metal-free direct decarbonylation of unstrained diaryl ketones via a dual C–C bond cleavage

The cleavage and formation of carbon−carbon bonds is an important strategy for structural modifications in organic syntheses. Herein, the authors present a photoinduced method to construct biaryl compounds through dual inert C−C bond cleavage.

Dawei Cao
Mohamad Ataya
Chao-Jun Li
ResearchOpen Access04 Apr 2022
Nature Communications

Volume: 13, P: 1-8
Engineering a photoactivatable A-to-I RNA base editor for gene therapy in vivo

A light-inducible RNA base editor fine-tunes gene expression for therapeutics.

Huiying Li
Yuhao Qiu
Dali Li
Research31 Mar 2025
Nature Biotechnology

P: 1-12
Chemotherapy and mismatch repair deficiency cooperate to fuel TP53 mutagenesis and ALL relapse

Zhou and colleagues demonstrate that thiopurine chemotherapy in mismatch repair-deficient ALL cells leads to R248Q TP53 mutations and clonal selection that favors on-treatment ALL relapse and chemoresistance.

Fan Yang
Samuel W. Brady
Bin-Bing S. Zhou
Research22 Jul 2021
Nature Cancer

Volume: 2, P: 819-834
Tracking-seq reveals the heterogeneity of off-target effects in CRISPR–Cas9-mediated genome editing

The off-target effects of any CRISPR-based genome editor are identified with Tracking-seq.

Ming Zhu
Runda Xu
Xun Lan
Research02 Jul 2024
Nature Biotechnology

Volume: 43, P: 799-810
A tripartite rheostat controls self-regulated host plant resistance to insects

Insect salivary protein (BISP) targets OsRLCK185 to suppress defence in susceptible plants, whereas in resistant plants BISP binds BPH14 to activate host plant resistance. To restore cellular homeostasis, the resistance mechanism is fine-tuned by selective autophagy.

Jianping Guo
Huiying Wang
Guangcun He
ResearchOpen Access14 Jun 2023
Nature

Volume: 618, P: 799-807
Dbh⁺ catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart

Catecholaminergic transmitters are critical signalling effectors known to be released by sympathetic nerves and adrenomedullary endocrine cells in response to physiological stress. In this paper, the authors demonstrate a uniquely distributed group of catecholaminergic cardiomyocytes with key regulatory roles in cardiac excitation conduction.

Tianyi Sun
Alexander Grassam-Rowe
Ming Lei
ResearchOpen Access28 Nov 2023
Nature Communications

Volume: 14, P: 1-23
Congenital heart disease detection by pediatric electrocardiogram based deep learning integrated with human concepts

Congenital heart disease is life threatening, and its screening is complex and costly. Here, authors use AI to detect the disease based on pediatric electrocardiogram, suggesting superior performance over cardiologists.

Jintai Chen
Shuai Huang
Huiying Liang
ResearchOpen Access01 Feb 2024
Nature Communications

Volume: 15, P: 1-13
Functional divergence of a bacterial enzyme promotes healthy or acneic skin

Cutibacterium acnes phylotypes can be catalogued based on their association with acneic or healthy skin. Here, Hajam et al show that the functional divergence of a hyaluronidase enzyme expressed by the phylotypes is a major determinant of acne severity.

Irshad A. Hajam
Madhusudhanarao Katiki
George Y. Liu
ResearchOpen Access05 Dec 2023
Nature Communications

Volume: 14, P: 1-14
Observation of frustrated chiral dynamics in an interacting triangular flux ladder

Synthetic gauge field in ultracold atoms provides a controllable platform for the study of quantum many-body physics. Here the authors demonstrate frustrated chiral dynamics in synthetic triangular flux ladder under strong interaction using ultracold Cs atoms.

Yuqing Li
Huiying Du
Suotang Jia
ResearchOpen Access20 Nov 2023
Nature Communications

Volume: 14, P: 1-7
Testing universality of Feynman-Tan relation in interacting Bose gases using high-order Bragg spectra

Yunfei Wang
Huiying Du
Suotang Jia
ResearchOpen Access28 Feb 2023
Light: Science & Applications

Volume: 12, P: 1-6
Structural insights into the mechanism of GTP initiation of microtubule assembly

In this study the authors explore the enigma of GTP-triggered microtubule assembly. The proposed flexible model emphasizes longitudinal and lateral contacts, enhancing our understanding of microtubule nucleation and assembly.

Ju Zhou
Anhui Wang
Hong-Wei Wang
ResearchOpen Access25 Sept 2023
Nature Communications

Volume: 14, P: 1-17
Atom-optically synthetic gauge fields for a noninteracting Bose gas

A two-leg ladder with tunable gauge fields is achieved by one-dimensional synthetic momentum-state lattice of a noninteracting Bose gas.

Yuqing Li
Jiahui Zhang
Suotang Jia
ResearchOpen Access07 Jan 2022
Light: Science & Applications

Volume: 11, P: 1-7
Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Huiying Gu
Zhizhong Ma
Yansheng Du
ResearchOpen Access28 Mar 2017
Scientific Reports

Volume: 7, P: 1-8
Bph6 encodes an exocyst-localized protein and confers broad resistance to planthoppers in rice

The study reports map-based cloning and functional analysis of Bph6, which is associated with resistance to planthoppers in rice. BPH6 localizes to the exocyst and interacts with OsEXO70E1, and suppression of OsExo70E1 expression decreases resistance in Bph6-NIL plants.

Jianping Guo
Chunxue Xu
Guangcun He
Research22 Jan 2018
Nature Genetics

Volume: 50, P: 297-306
UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis

UDP-glucose has a tumour-suppressive role by inhibiting the association between HuR and SNAI1 mRNA, whereas UGDH-mediated metabolism of UDP-glucose leads to increased SNAI1 mRNA stability and expression, thereby promoting tumour cell migration and lung cancer metastasis.

Xiongjun Wang
Ruilong Liu
Weiwei Yang
Research26 Jun 2019
Nature

Volume: 571, P: 127-131
No sex difference in the association of pre-stroke physical activity with functional independence after ischemic stroke

Shuangfang Fang
Baixiang Zhang
Houwei Du
ResearchOpen Access25 Apr 2025
Scientific Reports

Volume: 15, P: 1-10
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease

Integration of GWAS and single-cell transcriptomic data from the entire nervous system systematically identifies cell types underlying brain complex traits and provides insights into the etiology of Parkinson’s disease.

Julien Bryois
Nathan G. Skene
Patrick F. Sullivan
Research27 Apr 2020
Nature Genetics

Volume: 52, P: 482-493
d-PET-controlled “off-on” Polarity-sensitive Probes for Reporting Local Hydrophilicity within Lysosomes

Hao Zhu
Jiangli Fan
Xiaojun Peng
ResearchOpen Access21 Oct 2016
Scientific Reports

Volume: 6, P: 1-10
High sensitivity troponins and mortality in the population with metabolic dysfunction-associated steatotic liver disease

Jingjing Hu
Yuteng Du
Huiying Wang
ResearchOpen Access22 Aug 2024
Scientific Reports

Volume: 14, P: 1-11
Association between atrial cardiopathy and stroke severity in acute ischemic stroke

Yidan Zhang
Hanhan Lei
Houwei Du
ResearchOpen Access24 Jul 2024
Scientific Reports

Volume: 14, P: 1-8
Adipose-derived Stem Cell Conditioned Media Extends Survival time of a mouse model of Amyotrophic Lateral Sclerosis

Christine V. Fontanilla
Huiying Gu
Yansheng Du
ResearchOpen Access20 Nov 2015
Scientific Reports

Volume: 5, P: 1-11
Author Correction: Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Huiying Gu
Zhizhong Ma
Yansheng Du
Amendments and CorrectionsOpen Access25 Oct 2018
Scientific Reports

Volume: 8, P: 1
A Kaposi’s sarcoma-associated herpes virus-encoded microRNA contributes to dilated cardiomyopathy

Yanru Zhao
Huaping Li
Dao Wen Wang
ResearchOpen Access09 Jun 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-12
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner

Tong Yu
Yanyan Liu
Hongli Shan
ResearchOpen Access09 Jul 2022
Cell Death Discovery

Volume: 8, P: 1-14
Systematic analyses identify the anti-fibrotic role of lncRNA TP53TG1 in IPF

Jian Sun
Yingying Guo
Haihai Liang
ResearchOpen Access04 Jun 2022
Cell Death & Disease

Volume: 13, P: 1-13
Correction: Corrigendum: Adipose-derived Stem Cell Conditioned Media Extends Survival time of a mouse model of Amyotrophic Lateral Sclerosis

Christine V. Fontanilla
Huiying Gu
Yansheng Du
Amendments and CorrectionsOpen Access15 Apr 2016
Scientific Reports

Volume: 6, P: 1
Validation of the imatinib-therapy failure model

Xiaoshuai Zhang
Robert Peter Gale
Qian Jiang
Correspondence27 Mar 2023
Leukemia

Volume: 37, P: 1166-1169
The Yersinia Type III secretion effector YopM Is an E3 ubiquitin ligase that induced necrotic cell death by targeting NLRP3

Congwen Wei
Ying Wang
Xiang He
ResearchOpen Access08 Dec 2016
Cell Death & Disease

Volume: 7, P: e2519

Search

Observation of nonlinear edge states in an interacting atomic trimer array

Light-driven transition-metal-free direct decarbonylation of unstrained diaryl ketones via a dual C–C bond cleavage

Engineering a photoactivatable A-to-I RNA base editor for gene therapy in vivo

Chemotherapy and mismatch repair deficiency cooperate to fuel TP53 mutagenesis and ALL relapse

Tracking-seq reveals the heterogeneity of off-target effects in CRISPR–Cas9-mediated genome editing

A tripartite rheostat controls self-regulated host plant resistance to insects

Dbh⁺ catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart

Congenital heart disease detection by pediatric electrocardiogram based deep learning integrated with human concepts

Functional divergence of a bacterial enzyme promotes healthy or acneic skin

Observation of frustrated chiral dynamics in an interacting triangular flux ladder

Testing universality of Feynman-Tan relation in interacting Bose gases using high-order Bragg spectra

Structural insights into the mechanism of GTP initiation of microtubule assembly

Atom-optically synthetic gauge fields for a noninteracting Bose gas

Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Bph6 encodes an exocyst-localized protein and confers broad resistance to planthoppers in rice

UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis

No sex difference in the association of pre-stroke physical activity with functional independence after ischemic stroke

Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease

d-PET-controlled “off-on” Polarity-sensitive Probes for Reporting Local Hydrophilicity within Lysosomes

High sensitivity troponins and mortality in the population with metabolic dysfunction-associated steatotic liver disease

Association between atrial cardiopathy and stroke severity in acute ischemic stroke

Adipose-derived Stem Cell Conditioned Media Extends Survival time of a mouse model of Amyotrophic Lateral Sclerosis

Author Correction: Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

A Kaposi’s sarcoma-associated herpes virus-encoded microRNA contributes to dilated cardiomyopathy

Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner

Systematic analyses identify the anti-fibrotic role of lncRNA TP53TG1 in IPF

Correction: Corrigendum: Adipose-derived Stem Cell Conditioned Media Extends Survival time of a mouse model of Amyotrophic Lateral Sclerosis

Validation of the imatinib-therapy failure model

The Yersinia Type III secretion effector YopM Is an E3 ubiquitin ligase that induced necrotic cell death by targeting NLRP3

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