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Showing 1–7 of 7 results
Advanced filters: Author: Irene Cantone Clear advanced filters

  • Halide perovskites are promising for next generation photovoltaic technology but their environmental impact has not been fully evaluated. Here Li et al. show that the lead from perovskites is ten times more dangerous than lead-containing electronics while tin perovskites are much less bioavailable.

    • Junming Li
    • Hai-Lei Cao
    • Antonio Abate
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-5

  • Reactivation of the inactive X chromosome (Xi) has modelled epigenetic reprogramming in mouse. Here, by using cell fusion between human female fibroblasts and mouse embryonic stem cells, the authors show a complex hierarchy of epigenetic changes that are required to reactivate the genes on the human Xi chromosome.

    • Irene Cantone
    • Hakan Bagci
    • Amanda G. Fisher
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-12

  • Here, Bachmann et al. provide data on long-term dynamics of the HIV-1 reservoir in 1,057 individuals on suppressive antiretroviral therapy and show that in 26.6% of individuals the reservoir increases. Viral blips and low-level viremia are significantly associated with a slower reservoir decay.

    • Nadine Bachmann
    • Chantal von Siebenthal
    • Sabine Yerly
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11

  • Broadly neutralizing antibodies (bnAbs) develop in a minority of HIV-infected individuals. Analyzing data from more than 4,000 infected individuals, Alexandra Trkola and colleagues identify viral, host and disease factors associated with the development of bNAbs that may inform future vaccine design.

    • Peter Rusert
    • Roger D Kouyos
    • Rainer Weber
    Research
    Nature Medicine
    Volume: 22, P: 1260-1267

  • Global erasure and re-establishment of chromatin-based and DNA-based epigenetic marks occurs naturally in the mammalian life cycle, but it can also be artificially engineered using various reprogramming strategies. In this Review, recent advances in understanding how epigenetic remodeling contributes to cell-fate reprogramming in vivo and in vitro are summarized.

    • Irene Cantone
    • Amanda G Fisher
    Reviews
    Nature Structural & Molecular Biology
    Volume: 20, P: 282-289