The cell cycle governs a precise series of molecular events, regulated by coordinated changes in protein and phosphorylation abundance, that culminates in the generation of two daughter cells. Here, the authors present a proteomic and phosphoproteomic analysis of the human cell cycle in nontransformed cells using deep quantitative mass spectrometry by isobaric labelling.
- Camilla Rega
- Ifigenia Tsitsa
- Norman E. Davey
