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Showing 251–300 of 806 results

Advanced filters: Author: J D Ahn Clear advanced filters

Conformationally selective RNA aptamers allosterically modulate the β₂-adrenoceptor

Evolution of RNA aptamers that act allosterically by recognizing and stabilizing specific conformations, including active, inactive, and ligand-specific conformations of the GPCR β₂-adrenergic receptor, bound to pharmacologically distinct ligands.

Alem W Kahsai
James W Wisler
Robert J Lefkowitz
Research11 Jul 2016
Nature Chemical Biology

Volume: 12, P: 709-716
Author Correction: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig

Yulia Rubanova
Ruian Shi
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Predicting response to radical (chemo)radiotherapy with circulating HPV DNA in locally advanced head and neck squamous carcinoma

Jen Y Lee
Isaac Garcia-Murillas
Shreerang Bhide
ResearchOpen Access15 Aug 2017
British Journal of Cancer

Volume: 117, P: 876-883
Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower

Shimin Shuai
Federico Abascal
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

Kadir C. Akdemir
Victoria T. Le
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1079
Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes

Matthew A. Reyna
David Haan
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Butler enables rapid cloud-based analysis of thousands of human genomes

Sergei Yakneen
Sebastian M. Waszak
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Biotechnology

Volume: 41, P: 577
Author Correction: The repertoire of mutational signatures in human cancer

Ludmil B. Alexandrov
Jaegil Kim
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E41
Author Correction: Genomic basis for RNA alterations in cancer

Claudia Calabrese
Natalie R. Davidson
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E37
Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer

Lina Sieverling
Chen Hong
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Bernardo Rodriguez-Martin
Eva G. Alvarez
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1080
Author Correction: Integrative pathway enrichment analysis of multivariate omics data

Marta Paczkowska
Jonathan Barenboim
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations

Yiqun Zhang
Fengju Chen
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Inferring structural variant cancer cell fraction

Marek Cmero
Ke Yuan
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: The evolutionary history of 2,658 cancers

Moritz Gerstung
Clemency Jolly
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E42
Author Correction: Patterns of somatic structural variation in human cancer genomes

Yilong Li
Nicola D. Roberts
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E38
Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

Wei Jiao
Gurnit Atwal
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Isidro Cortés-Ciriano
Jake June-Koo Lee
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1076
Centennial-scale changes in the global carbon cycle during the last deglaciation

Carbon dioxide and methane records from a West Antarctic ice core show that although gradual variations in the concentration of atmospheric carbon dioxide during the last glacial termination are linked to changes in Antarctic temperature, the concentration underwent three abrupt, centennial-scale changes related to sudden climate changes in the Northern Hemisphere.

Shaun A. Marcott
Thomas K. Bauska
Edward J. Brook
Research29 Oct 2014
Nature

Volume: 514, P: 616-619
Controlling polymer shape through the self-assembly of dendritic side-groups

V. Percec
C.-H. Ahn
S. S. Sheiko
Research08 Jan 1998
Nature

Volume: 391, P: 161-164
Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers

Yuan Yuan
Young Seok Ju
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1078
Weight change in adulthood and risk of postmenopausal breast cancer: the HUNT study of Norway

M D K Alsaker
I Janszky
P R Romundstad
ResearchOpen Access23 Jul 2013
British Journal of Cancer

Volume: 109, P: 1310-1317
Author Correction: Divergent mutational processes distinguish hypoxic and normoxic tumours

Vinayak Bhandari
Constance H. Li
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Pan-cancer analysis of whole genomes

Lauri A. Aaltonen
Federico Abascal
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E39
Author Correction: The landscape of viral associations in human cancers

Marc Zapatka
Ivan Borozan
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1077
Nutraceuticals and prostate cancer prevention: a current review

Several naturally occurring substances have been implicated in the prevention of prostate cancer, but the lack of randomized controlled trials means causal effect has not yet been demonstrated. Here, the authors summarize existing data on a number of promising compounds and discuss the future direction of clinical trials in this field.

Greg Trottier
Peter J. Boström
Neil E. Fleshner
Reviews08 Dec 2009
Nature Reviews Urology

Volume: 7, P: 21-30
T-box gene tbx5 is essential for formation of the pectoral limb bud

Dae-gwon Ahn
Matthew J. Kourakis
Robert K. Ho
Research13 Jun 2002
Nature

Volume: 417, P: 754-758
Comprehensive genomic characterization of head and neck squamous cell carcinomas

The Cancer Genome Atlas presents an integrative genome-wide analysis of genetic alterations in 279 head and neck squamous cell carcinomas (HNSCCs), which are classified by human papillomavirus (HPV) status; alterations in EGFR, FGFR, PIK3CA and cyclin-dependent kinases are shown to represent candidate targets for therapeutic intervention in most HNSCCs.

Michael S. Lawrence
Carrie Sougnez
Wendell G. Yarbrough
ResearchOpen Access28 Jan 2015
Nature

Volume: 517, P: 576-582
Only the chemical state of Indium changes in Mn-doped In₃Sb₁Te₂ (Mn: 10 at.%) during multi-level resistance changes

Y. M. Lee
D. Ahn
Y. B. Qi
ResearchOpen Access16 Apr 2014
Scientific Reports

Volume: 4, P: 1-4
Microchannel pressure sensor for continuous and real-time wearable gait monitoring

Wearable pressure sensors can track body movements for diagnostic purposes. Here, a microchannel architecture in a flexible sensor enables comprehensive analysis of static and dynamic pressure when attached to a foot, allowing for detailed analysis of walking gait.

Jung-Bin Ahn
Byungseok Yoo
Soaram Kim
ResearchOpen Access24 Jul 2024
Communications Materials

Volume: 5, P: 1-9
Microvasculature-on-a-chip for the long-term study of endothelial barrier dysfunction and microvascular obstruction in disease

An endothelialized microfluidic system that recapitulates physiological properties of the microvasculature enables the real-time visualization of vascular-pathology features associated with sickle-cell disease and malaria, with high spatiotemporal resolution.

Yongzhi Qiu
Byungwook Ahn
Wilbur A. Lam
Research23 Apr 2018
Nature Biomedical Engineering

Volume: 2, P: 453-463
Antibacterial effects of nanopillar surfaces are mediated by cell impedance, penetration and induction of oxidative stress

Synthetic nanopillars resembling the wing surface of certain insects display antibacterial activities. Here, Jenkins et al. show that these activities do not necessarily require bacterial lysis, and may be mediated by oxidative stress induced by deformation of the bacterial cell envelope.

J. Jenkins
J. Mantell
B. Su
ResearchOpen Access02 Apr 2020
Nature Communications

Volume: 11, P: 1-14
Author Correction: Modulating co-translational protein folding by rational design and ribosome engineering

Minkoo Ahn
Tomasz Włodarski
John Christodoulou
Amendments and CorrectionsOpen Access16 Sept 2022
Nature Communications

Volume: 13, P: 1
Trodusquemine enhances Aβ₄₂ aggregation but suppresses its toxicity by displacing oligomers from cell membranes

Transient oligomeric species of the amyloid-β peptide (Aβ₄₂) have been identified as key pathogenic agents in Alzheimer’s disease. Here the authors find that the aminosterol trodusquemine enhances Aβ₄₂ aggregation and suppresses Aβ₄₂-induced toxicity by displacing oligomers from cell membranes.

Ryan Limbocker
Sean Chia
Christopher M. Dobson
ResearchOpen Access15 Jan 2019
Nature Communications

Volume: 10, P: 1-13
ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior

Upregulation of the ATP-dependent ACF chromatin-remodeling complex in the NAc is a necessary and causal component for susceptibility to stress-induced depressive behaviors in mice, and this complex is also shown to be upregulated in the NAc of depressed humans.

HaoSheng Sun
Diane M Damez-Werno
Eric J Nestler
Research21 Sept 2015
Nature Medicine

Volume: 21, P: 1146-1153
Pharmaceutical and clinical implications of proton pump inhibitors with dual antiplatelet therapies: a systematic review

Jacob J. Gries
George Triadafilopoulos
Chayakrit Krittanawong
ResearchOpen Access10 Jan 2025
npj Gut and Liver

Volume: 2, P: 1-15
Grip strength as a surrogate measure of strength, functional, and metabolic parameter increases in breast cancer survivors undergoing an exercise regimen

Colin E. Champ
Chris Peluso
David J. Carpenter
ResearchOpen Access06 May 2025
Scientific Reports

Volume: 15, P: 1-7
Results of an abbreviated phase-II study with the Akt Inhibitor MK-2206 in Patients with Advanced Biliary Cancer

Daniel H. Ahn
Junan Li
Tanios Bekaii-Saab
ResearchOpen Access10 Jul 2015
Scientific Reports

Volume: 5, P: 1-8
Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease

Asparagine endopeptidase (AEP) cleaves human α-synuclein at Asn103, yielding a fragment with higher aggregation propensity than that of the full-length protein. Truncated α-synuclein is also more neurotoxic and leads to dopaminergic neuronal loss and motor impairments in mice.

Zhentao Zhang
Seong Su Kang
Keqiang Ye
Research03 Jul 2017
Nature Structural & Molecular Biology

Volume: 24, P: 632-642
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk

Wei Zheng and colleagues report the results of a large-scale genome-wide association study of colorectal cancer in East Asians. They identify six new susceptibility loci, including variants near TCF7L2 and TGFB1.

Ben Zhang
Wei-Hua Jia
Wei Zheng
Research18 May 2014
Nature Genetics

Volume: 46, P: 533-542
The Ghana Science Association

J. YANNEY-WILSON
News15 Sept 1962
Nature

Volume: 195, P: 1055-1056
Association and linkage of LDLR gene variation with variation in plasma low density lipoprotein cholesterol

Andrew P. Boright
Phillip W. Connelly
R. A. Hegele
Research01 Sept 1998
Journal of Human Genetics

Volume: 43, P: 153-159
Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Matthew H. Bailey
William U. Meyerson
Christian von Mering
Amendments and CorrectionsOpen Access30 Nov 2020
Nature Communications

Volume: 11, P: 1
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

The UK IBD Genetics Consortium and the Wellcome Trust Case Control Consortium 2 report results of a genome-wide association study of ulcerative colitis. They identify three new loci associated with the disease, including the HNF4A region on 20q13.

Jeffrey C Barrett
James C Lee
David P Strachan
Research15 Nov 2009
Nature Genetics

Volume: 41, P: 1330-1334
Specific retinoid receptors cooperate to signal growth suppression and maturation of human embryonal carcinoma cells

Michael J Spinella
Sutisak Kitareewan
Ethan Dmitrovsky
Research14 Jul 1998
Oncogene

Volume: 16, P: 3471-3480
Surface-initiated self-healing of polymers in aqueous media

Synthetic polymers functionalized with mussel-inspired catechols have been shown to exhibit self-healing and adhesive properties, mediated by metal chelation, that are much needed in biomedical and environmental applications. Now, a metal-free approach to complete polymer self-healing underwater mediated by extensive hydrogen bonding in catechol-functionalized polyacrylates is reported.

B. Kollbe Ahn
Dong Woog Lee
J. Herbert Waite
Research27 Jul 2014
Nature Materials

Volume: 13, P: 867-872
Author Correction: Resonantly hybridized excitons in moiré superlattices in van der Waals heterostructures

Evgeny M. Alexeev
David A. Ruiz-Tijerina
Alexander I. Tartakovskii
Amendments and Corrections16 Jul 2019
Nature

Volume: 572, P: E8
Bidirectional Control of Anxiety-Related Behaviors in Mice: Role of Inputs Arising from the Ventral Hippocampus to the Lateral Septum and Medial Prefrontal Cortex

Gustavo Morrone Parfitt
Robin Nguyen
Jun Chul Kim
Research15 Mar 2017
Neuropsychopharmacology

Volume: 42, P: 1715-1728
Butterfly genome reveals promiscuous exchange of mimicry adaptations among species

Sequencing of the genome of the butterfly Heliconius melpomene shows that closely related Heliconius species exchange protective colour-pattern genes promiscuously.

Kanchon K. Dasmahapatra
James R. Walters
Chris D. Jiggins
ResearchOpen Access16 May 2012
Nature

Volume: 487, P: 94-98
Head and neck cancer relapse after chemoradiotherapy correlates with CD163+ macrophages in primary tumour and CD11b+ myeloid cells in recurrences

P Balermpas
F Rödel
E Fokas
ResearchOpen Access05 Aug 2014
British Journal of Cancer

Volume: 111, P: 1509-1518

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