Nature Search

Intracellular pH and cytoplasmic free Ca²⁺

W. Siffert
J. W. N. Akkerman
Research04 Jun 1987
Nature

Volume: 327, P: 376
How many Chernobyl fatalities?

J. H. Fremlin
Research04 Jun 1987
Nature

Volume: 327, P: 376
Intracellular pH and cytoplasmic free Ca²⁺

T. J. Rink
Research04 Jun 1987
Nature

Volume: 327, P: 375-376
Sequencing proteins from acrylamide gels

The analytical power of high-resolution two-dimensional gel electrophoresis has been coupled with mol-ecular cloning techniques to allow the sequencing of proteins directly from preparative gels.

T. E. Kennedy
K. Wager-Smith
J. D. Sweatt
Comments & Opinion01 Dec 1988
Nature

Volume: 336, P: 499-500
FMRFamide reverses protein phosphorylation produced by 5-HT and cAMP in Aplysia sensory neurons

J. David Sweatt
Andrea Volterra
Eric R. Kandel
Research16 Nov 1989
Nature

Volume: 342, P: 275-278
Persistent and transcriptionally-dependent increase in protein phosphorylation in long-term facilitation ofAplysia sensory neurons

J. David Sweatt
Eric R. Kandel
Research04 May 1989
Nature

Volume: 339, P: 51-54
G₀ is a major growth cone protein subject to regulation by GAP-43

Stephen M. Strittmatter
Dario Valenzuela
Mark C. Fishman
Research26 Apr 1990
Nature

Volume: 344, P: 836-841
Patch clamp studies of single cell-fusion events mediated by a viral fusion protein

A. E. Spruce
A. Iwata
W. Almers
Research30 Nov 1989
Nature

Volume: 342, P: 555-558
White-light velocimetry

David J. Erskine
Neil C. Holmes
Research28 Sept 1995
Nature

Volume: 377, P: 317-320
Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory

Circadian rhythms are known to modulate memory, but it’s not known whether clock genes in the hippocampus are required for memory consolidation. Here, the authors show that epigenetic regulation of clock gene Period1 in the hippocampus regulates memory and contributes to age-related memory decline, independent of circadian rhythms.

Janine L. Kwapis
Yasaman Alaghband
Marcelo A. Wood
ResearchOpen Access20 Aug 2018
Nature Communications

Volume: 9, P: 1-14
Coupling of bitter receptor to phosphodiesterase through transducin in taste receptor cells

Luis Ruiz-Avila
Susan K. McLaughlin
Robert F. Margolskee
Research06 Jul 1995
Nature

Volume: 376, P: 80-85
Histone H2A.Z subunit exchange controls consolidation of recent and remote memory

The authors identify a specific histone variant as a memory-suppressor that is initially reduced in expression within the hippocampus during memory formation; as a memory is consolidated to the cortex, reduced histone association with specific plasticity genes is observed, promoting stabilization of the memory.

Iva B. Zovkic
Brynna S. Paulukaitis
J. David Sweatt
Research14 Sept 2014
Nature

Volume: 515, P: 582-586
Epigenetic Mechanisms for the Early Environmental Regulation of Hippocampal Glucocorticoid Receptor Gene Expression in Rodents and Humans

Tie Yuan Zhang
Benoit Labonté
Michael J Meaney
Reviews12 Sept 2012
Neuropsychopharmacology

Volume: 38, P: 111-123
Abnormal Activity of the MAPK- and cAMP-Associated Signaling Pathways in Frontal Cortical Areas in Postmortem Brain in Schizophrenia

Adam J Funk
Robert E McCullumsmith
James H Meador-Woodruff
Research02 Nov 2011
Neuropsychopharmacology

Volume: 37, P: 896-905
DNA methylation regulates associative reward learning

This study shows that associative reward learning produces dynamic experience-dependent alterations in DNA methylation and immediate-early gene expression in ventral tegmental area (VTA) dopamine neurons and that DNA methylation in the VTA is required for the formation of new reward-related memories.

Jeremy J Day
Daniel Childs
J David Sweatt
Research25 Aug 2013
Nature Neuroscience

Volume: 16, P: 1445-1452
DNA methylation and memory formation

Disruption of DNA methylation in the brain can impair learning and memory in rodents. In this Perspective, Day and Sweatt provide an overview of evidence that implicates this epigenetic mechanism in memory processes and discuss how past controversies can be explained in light of recent findings.

Jeremy J Day
J David Sweatt
Reviews26 Oct 2010
Nature Neuroscience

Volume: 13, P: 1319-1323
Cortical DNA methylation maintains remote memory

The authors report that persistent, gene-specific hypermethylation is induced by associative learning and that inhibition of methylation long after learning disrupts remote memory. This suggests that DNA methylation may be a mechanism for preserving long-lasting memories.

Courtney A Miller
Cristin F Gavin
J David Sweatt
Research23 May 2010
Nature Neuroscience

Volume: 13, P: 664-666
A myelin-related transcriptomic profile is shared by Pitt–Hopkins syndrome models and human autism spectrum disorder

The authors identify an impaired myelination signature from the brains of mouse models of Pitt–Hopkins syndrome and show that it is shared in the postmortem brains of people with autism.

BaDoi N. Phan
Joseph F. Bohlen
Brady J. Maher
Research03 Feb 2020
Nature Neuroscience

Volume: 23, P: 375-385
Extra-coding RNAs regulate neuronal DNA methylation dynamics

DNA methylation in the brain is a dynamic process, but gene-specific regulation of this process is poorly understood. Here, Day and colleagues show that extra-coding RNAs interact with DNA methyltransferases and regulate neuronal DNA methylation to control gene expression in locus-specific manner in neurons.

Katherine E. Savell
Nancy V. N. Gallus
Jeremy J. Day
ResearchOpen Access07 Jul 2016
Nature Communications

Volume: 7, P: 1-14
The MAPK cascade is required for mammalian associative learning

Coleen M. Atkins
Joel C. Selcher
J. David Sweatt
Research01 Nov 1998
Nature Neuroscience

Volume: 1, P: 602-609
Neurochemical Sensitization in the Pathophysiology of Schizophrenia: Deficits and Dysfunction in Neuronal Regulation and Plasticity

Jeffrey A Lieberman
Brian B Sheitman
Bruce J Kinon
Reviews01 Oct 1997
Neuropsychopharmacology

Volume: 17, P: 205-229
Neuroplasticity Mediated by Altered Gene Expression

Colleen A McClung
Eric J Nestler
Reviews29 Aug 2007
Neuropsychopharmacology

Volume: 33, P: 3-17
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

In dividing cells, the epigenetic mechanism of DNA methylation is catalyzed by enzymes that maintain DNA methylation or act as a de novo methyltransferase. In this study, the authors find that DNA methyltransferases Dnmt1 and 3a have an active role in the maintenance of DNA methylation in postmitotic excitatory neurons. Results indicate that there is a redundancy between the two enzymes in neurons and that DNA methylation is essential for normal synaptic plasticity and memory formation.

Jian Feng
Yu Zhou
Guoping Fan
Research14 Mar 2010
Nature Neuroscience

Volume: 13, P: 423-430
Long-term potentiation and contextual fear conditioning increase neuronal glutamate uptake

Jonathan Levenson
Edwin Weeber
Arnold Eskin
Research14 Jan 2002
Nature Neuroscience

Volume: 5, P: 155-161
Multimedia and virtual reality techniques in the treatment of male erectile disorders

G Optale
A Munari
G Viggiano
Research01 Dec 1997
International Journal of Impotence Research

Volume: 9, P: 197-203
PACAP and the PAC1 Receptor in Post-Traumatic Stress Disorder

Brian G Dias
Kerry J Ressler
Research13 Nov 2012
Neuropsychopharmacology

Volume: 38, P: 245-246
General Summary

A Martin
J Licinio
Research17 Apr 2001
Molecular Psychiatry

Volume: 6, P: 119-123
Craving cocaine pERKs up the amygdala

Yarimar Carrasquillo
J David Sweatt
News & Views01 Feb 2005
Nature Neuroscience

Volume: 8, P: 129-130
Pharmacological Selectivity Within Class I Histone Deacetylases Predicts Effects on Synaptic Function and Memory Rescue

Gavin Rumbaugh
Stephanie E Daws
Courtney A Miller
Research03 Apr 2015
Neuropsychopharmacology

Volume: 40, P: 2307-2316
Augmentation of phenylbutyrate-induced differentiation of myeloid leukemia cells using all-trans retinoic acid

KH Yu
L-J Weng
SD Gore
Research09 Aug 1999
Leukemia

Volume: 13, P: 1258-1265
Pitt–Hopkins Syndrome: intellectual disability due to loss of TCF4-regulated gene transcription

J David Sweatt
ReviewsOpen Access03 May 2013
Experimental & Molecular Medicine

Volume: 45, P: e21
Roles of serine/threonine phosphatases in hippocampel synaptic plasticity

Danny G. Winder
J. David Sweatt
Reviews01 Jul 2001
Nature Reviews Neuroscience

Volume: 2, P: 461-474
Olfactory Receptor Neuron Dysfunction in Schizophrenia

Bruce I Turetsky
Chang-Gyu Hahn
Paul J Moberg
Research27 Aug 2008
Neuropsychopharmacology

Volume: 34, P: 767-774
Epigenetic mechanisms in memory formation

Jonathan M. Levenson
J. David Sweatt
Reviews14 Jan 2005
Nature Reviews Neuroscience

Volume: 6, P: 108-118
Enhancement of Fear Extinction with Deep Brain Stimulation: Evidence for Medial Orbitofrontal Involvement

Jose Rodriguez-Romaguera
Fabricio H Do-Monte
Suzanne N Haber
Research20 Jan 2015
Neuropsychopharmacology

Volume: 40, P: 1726-1733
Chemogenetic Inactivation of Ventral Hippocampal Glutamatergic Neurons Disrupts Consolidation of Contextual Fear Memory

Hu Zhu
Kristen E Pleil
Bryan L Roth
Research14 Feb 2014
Neuropsychopharmacology

Volume: 39, P: 1880-1892
Interactions Between Age, Stress and Insulin on Cognition: Implications for Alzheimer's Disease

Maite Solas
Bárbara Aisa
María J Ramírez
Research24 Feb 2010
Neuropsychopharmacology

Volume: 35, P: 1664-1673
Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors

Jian Feng
Catherine J Pena
Eric J Nestler
Research11 Jan 2017
Neuropsychopharmacology

Volume: 42, P: 1657-1669
Cognitive Deficits in Rats after Forebrain Cholinergic Depletion are Reversed by a Novel NO Mimetic Nitrate Ester

Brian M Bennett
James N Reynolds
Gregory R J Thatcher
Research08 Mar 2006
Neuropsychopharmacology

Volume: 32, P: 505-513
Constitutive Activation of Gαs within Forebrain Neurons Causes Deficits in Sensorimotor Gating Because of PKA-Dependent Decreases in cAMP

Michele P Kelly
Carolina Isiegas
Ted Abel
Research31 May 2006
Neuropsychopharmacology

Volume: 32, P: 577-588
Corticostriatal Afferents Modulate Responsiveness to Psychostimulant Drugs and Drug-Associated Stimuli

K A Kerstetter
A M Wunsch
Susan M Ferguson
Research20 Aug 2015
Neuropsychopharmacology

Volume: 41, P: 1128-1137
Effects of Inhibitor of κB Kinase Activity in the Nucleus Accumbens on Emotional Behavior

Daniel J Christoffel
Sam A Golden
Scott J Russo
Research11 Jul 2012
Neuropsychopharmacology

Volume: 37, P: 2615-2623
The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation

Brandon J Walters
Valentina Mercaldo
Sheena A Josselyn
Research16 Feb 2017
Neuropsychopharmacology

Volume: 42, P: 1502-1510
Hyposensitivity to Gamma-Aminobutyric Acid in the Ventral Tegmental Area During Alcohol Withdrawal: Reversal by Histone Deacetylase Inhibitors

Devinder S Arora
Sudarat Nimitvilai
Mark S Brodie
Research08 Mar 2013
Neuropsychopharmacology

Volume: 38, P: 1674-1684
Inhibitory effects of omega-3 fatty acids on protein kinase C activity in vitro

H F Seung Kim
E J Weeber
L B Marangell
Research17 Apr 2001
Molecular Psychiatry

Volume: 6, P: 246-248
Late-phase long-term potentiation: getting to the nucleus

J. Paige Adams
Serena M. Dudek
Reviews01 Sept 2005
Nature Reviews Neuroscience

Volume: 6, P: 737-743
Neural Mechanisms of Extinction Learning and Retrieval

Gregory J Quirk
Devin Mueller
Reviews19 Sept 2007
Neuropsychopharmacology

Volume: 33, P: 56-72
Reduced Expression of the NMDA Receptor-Interacting Protein SynGAP Causes Behavioral Abnormalities that Model Symptoms of Schizophrenia

Xiaochuan Guo
Peter J Hamilton
Gavin Rumbaugh
Research14 Jan 2009
Neuropsychopharmacology

Volume: 34, P: 1659-1672
Deficiency in the Inhibitory Serine-Phosphorylation of Glycogen Synthase Kinase-3 Increases Sensitivity to Mood Disturbances

Abigail Polter
Eléonore Beurel
Richard S Jope
Research31 Mar 2010
Neuropsychopharmacology

Volume: 35, P: 1761-1774
Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

Mark Kilgore
Courtney A Miller
Gavin Rumbaugh
Research09 Dec 2009
Neuropsychopharmacology

Volume: 35, P: 870-880

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