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International Journal of Obesity (16)
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Showing 1–21 of 21 results

Advanced filters: Author: J M Moreno-Navarrete Clear advanced filters

Defective Olfactomedin-2 connects adipocyte dysfunction to obesity

Olfactomedin-2 is a pleiotropic glycoprotein emerging as a regulator of energy homeostasis via the hypothalamus. The present findings functionally connect adipose-specific OLFM2 to obesity, and highlight its significance in maintaining adipocyte commitment to avoid metabolic disease.

Aina Lluch
Jèssica Latorre
Francisco J. Ortega
ResearchOpen Access04 Aug 2025
Nature Communications

Volume: 16, P: 1-25
Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance

Obesity-associated AT fibro-inflammation and metabolic disturbances are linked to PEPD activity and PEPD extracellular levels.

V. Pellegrinelli
S. Rodriguez-Cuenca
A. Vidal-Puig
Research25 Apr 2022
Nature Metabolism

Volume: 4, P: 476-494
Correction: Corrigendum: Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness

Nicholas M Morton
Jasmina Beltram
Simon Horvat
Amendments and Corrections01 Apr 2018
Nature Medicine

Volume: 24, P: 525
Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence

Plakophilin-2 is a key component of desmosomes required to maintain cardiac tissue cohesion. Here the authors uncover a previously unknown defect in cell cycle and adipocyte senescence due to impaired Plakophilin-2 in subjects with obesity.

Aina Lluch
Jessica Latorre
Francisco J. Ortega
ResearchOpen Access22 Aug 2023
Nature Communications

Volume: 14, P: 1-21
Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness

Genetic analysis in mice selected for leanness has identified thiosulfate sulfurtransferase as a target for the treatment of diabetes.

Nicholas M Morton
Jasmina Beltram
Simon Horvat
Research06 Jun 2016
Nature Medicine

Volume: 22, P: 771-779
Telomere length of subcutaneous adipose tissue cells is shorter in obese and formerly obese subjects

J M Moreno-Navarrete
F Ortega
J M Fernández-Real
Research16 Mar 2010
International Journal of Obesity

Volume: 34, P: 1345-1348
Lactoferrin increases ^172ThrAMPK phosphorylation and insulin-induced ^p473SerAKT while impairing adipocyte differentiation

J M Moreno-Navarrete
F J Ortega
J M Fernandez-Real
Research04 Aug 2009
International Journal of Obesity

Volume: 33, P: 991-1000
Type I iodothyronine 5′-deiodinase mRNA and activity is increased in adipose tissue of obese subjects

F J Ortega
Z M Jílková
J M Fernández-Real
Research24 May 2011
International Journal of Obesity

Volume: 36, P: 320-324
Deletion of G-protein-coupled receptor 55 promotes obesity by reducing physical activity

A Meadows
J H Lee
Y Sun
Research08 Oct 2015
International Journal of Obesity

Volume: 40, P: 417-424
Circulating soluble transferrin receptor concentration decreases after exercise-induced improvement of insulin sensitivity in obese individuals

J M Fernández-Real
M Izquierdo
J Ibañez
Research02 Jun 2009
International Journal of Obesity

Volume: 33, P: 768-774
Liver, but not adipose tissue PEDF gene expression is associated with insulin resistance

J M Moreno-Navarrete
V Touskova
J M Fernández-Real
Research15 Jan 2013
International Journal of Obesity

Volume: 37, P: 1230-1237
Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD

J Latorre
J M Moreno-Navarrete
F J Ortega
Research25 Jan 2017
International Journal of Obesity

Volume: 41, P: 620-630
Thyroid hormone responsive Spot 14 increases during differentiation of human adipocytes and its expression is down-regulated in obese subjects

F J Ortega
A Vazquez-Martin
J-M Fernández-Real
Research22 Dec 2009
International Journal of Obesity

Volume: 34, P: 487-499
Inflammation and insulin resistance exert dual effects on adipose tissue tumor protein 53 expression

F J Ortega
J M Moreno-Navarrete
J M Fernández-Real
Research03 Sept 2013
International Journal of Obesity

Volume: 38, P: 737-745
The lung innate immune gene surfactant protein-D is expressed in adipose tissue and linked to obesity status

F J Ortega
N Pueyo
J M Fernández-Real
Research12 Mar 2013
International Journal of Obesity

Volume: 37, P: 1532-1538
CIDEC/FSP27 and PLIN1 gene expression run in parallel to mitochondrial genes in human adipose tissue, both increasing after weight loss

J M Moreno-Navarrete
F Ortega
J M Fernández-Real
Research12 Sept 2013
International Journal of Obesity

Volume: 38, P: 865-872
Circulating lipopolysaccharide-binding protein (LBP) as a marker of obesity-related insulin resistance

J M Moreno-Navarrete
F Ortega
J M Fernández-Real
Research20 Dec 2011
International Journal of Obesity

Volume: 36, P: 1442-1449
Metabolic endotoxemia and saturated fat contribute to circulating NGAL concentrations in subjects with insulin resistance

J M Moreno-Navarrete
M Manco
J M Fernández-Real
Research01 Dec 2009
International Journal of Obesity

Volume: 34, P: 240-249
Neuroinflammation in obesity: circulating lipopolysaccharide-binding protein associates with brain structure and cognitive performance

J M Moreno-Navarrete
G Blasco
J M Fernández-Real
Research07 Jul 2017
International Journal of Obesity

Volume: 41, P: 1627-1635
LIGHT is associated with hypertriglyceridemia in obese subjects and increased cytokine secretion from cultured human adipocytes

J Bassols
J M Moreno-Navarrete
J M Fernandez-Real
Research29 Sept 2009
International Journal of Obesity

Volume: 34, P: 146-156
Circulating irisin levels and coronary heart disease: association with future acute coronary syndrome and major adverse cardiovascular events

K N Aronis
M Moreno
C S Mantzoros
Research11 Jun 2014
International Journal of Obesity

Volume: 39, P: 156-161

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Defective Olfactomedin-2 connects adipocyte dysfunction to obesity

Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance

Correction: Corrigendum: Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness

Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence

Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness

Telomere length of subcutaneous adipose tissue cells is shorter in obese and formerly obese subjects

Lactoferrin increases ^172ThrAMPK phosphorylation and insulin-induced ^p473SerAKT while impairing adipocyte differentiation

Type I iodothyronine 5′-deiodinase mRNA and activity is increased in adipose tissue of obese subjects

Deletion of G-protein-coupled receptor 55 promotes obesity by reducing physical activity

Circulating soluble transferrin receptor concentration decreases after exercise-induced improvement of insulin sensitivity in obese individuals

Liver, but not adipose tissue PEDF gene expression is associated with insulin resistance

Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD

Thyroid hormone responsive Spot 14 increases during differentiation of human adipocytes and its expression is down-regulated in obese subjects

Inflammation and insulin resistance exert dual effects on adipose tissue tumor protein 53 expression

The lung innate immune gene surfactant protein-D is expressed in adipose tissue and linked to obesity status

CIDEC/FSP27 and PLIN1 gene expression run in parallel to mitochondrial genes in human adipose tissue, both increasing after weight loss

Circulating lipopolysaccharide-binding protein (LBP) as a marker of obesity-related insulin resistance

Metabolic endotoxemia and saturated fat contribute to circulating NGAL concentrations in subjects with insulin resistance

Neuroinflammation in obesity: circulating lipopolysaccharide-binding protein associates with brain structure and cognitive performance

LIGHT is associated with hypertriglyceridemia in obese subjects and increased cytokine secretion from cultured human adipocytes

Circulating irisin levels and coronary heart disease: association with future acute coronary syndrome and major adverse cardiovascular events

Search

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