An extensive comparative genomic analysis of thermophilic, thermotolerant, and mesophilic fungi genomes is used to define features of thermophily and shows the power of integrating phylogenetic analysis with machine learning and AlphaFold2 to obtain insights into the evolutionary origins of a specific physiology.
- Andrei S. Steindorff
- Maria Victoria Aguilar-Pontes
- Igor V. Grigoriev
