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Showing 51–100 of 461 results

Advanced filters: Author: J. van Leeuwen Clear advanced filters

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

A region on chromosome 19p13 is associated with the risk of developing ovarian and breast cancer. Here, the authors genotyped SNPs in this region in thousands of breast and ovarian cancer patients and identified SNPs associated with three genes, which were analysed with functional studies.

Kate Lawrenson
Siddhartha Kar
Simon A. Gayther
ResearchOpen Access07 Sept 2016
Nature Communications

Volume: 7, P: 1-22
Effects of β-Mercaptoethanol on Morphogenesis in Amphibian Eggs

J. BRACHET
Research21 Jun 1958
Nature

Volume: 181, P: 1736-1737
Long-Term Effects of Treatment for Acute Lymphoblastic Leukemia with and without Cranial Irradiation on Growth and Puberty: A Comparative Study

A C S Hokken-Koelega
J W D Van Doorn
S L S Drop
Research01 Jun 1993
Pediatric Research

Volume: 33, P: 577-582
Detection of a novel human class II HLA antigen

Andrew J. Watson
Robert DeMars
Fritz H. Bach
Research28 Jul 1983
Nature

Volume: 304, P: 358-361
Second primary malignancies after treatment for malignant lymphoma

A Okines
C S Thomson
B W Hancock
ResearchOpen Access16 Aug 2005
British Journal of Cancer

Volume: 93, P: 418-424
Biochemical Studies in the Liver and Muscle of Patients with Zellweger Syndrome

J M F Trijbels
J A Berden
M Van Den Broek-Van Essen
Research01 Jun 1983
Pediatric Research

Volume: 17, P: 514-517
Role of ABO Erthrocyte Groups in Human Histocompatibility Reactions

J. DAUSSET
F. T. RAPAPORT
Research08 Jan 1966
Nature

Volume: 209, P: 209-211
Phosphatidylinositol-3-OH kinase direct target of Ras

Pablo Rodriguez-Viciana
Patricia H. Warne
Julian Downward
Research18 Aug 1994
Nature

Volume: 370, P: 527-532
Interruption of SV40 Oncogenesis with Human Foetal Antigen

K. R. AMBROSE
N. G. ANDERSON
J. H. COGGIN
Research17 Sept 1971
Nature

Volume: 233, P: 194-195
Late Effects among Long-Term Survivors of Childhood Acute Leukemia in The Netherlands: A Dutch Childhood Leukemia Study Group Report

A Van Der Does-Van Den Berg
G A M De Vaan
A J P Veerman
Research01 Nov 1995
Pediatric Research

Volume: 38, P: 802-807
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Fine-mapping of causal variants and integration of epigenetic and chromatin conformation data identify likely target genes for 150 breast cancer risk regions.

Laura Fachal
Hugues Aschard
Alison M. Dunning
Research07 Jan 2020
Nature Genetics

Volume: 52, P: 56-73
Labelled Tyrosinase from Labelled Substrate

B. J. B. WOOD
L. L. INGRAHAM
Research16 Jan 1965
Nature

Volume: 205, P: 291-292
Identification of a new oncofoetal antigen associated with several types of human carcinomas

R. FRITSCHÉ
J.-P. MACH
Research25 Dec 1975
Nature

Volume: 258, P: 734-737
A rigid body framework for multicellular modeling

The authors present a framework for modeling cell interactions using rigid bodies, which can used to represent cells as free moving polygons, to allow epithelial layers to smoothly interact, to model bacteria and to robustly represent membranes.

Phillip J. Brown
J. Edward F. Green
James M. Osborne
Research25 Nov 2021
Nature Computational Science

Volume: 1, P: 754-766
Analysis of fibroblast proteins from patients with Duchenne muscular dystrophy by two-dimensional gel electrophoresis

E. Rosenmann
C. Kreis
K. Wrogemann
Research05 Aug 1982
Nature

Volume: 298, P: 563-565
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

An expanded GWAS of birth weight and subsequent analysis using structural equation modeling and Mendelian randomization decomposes maternal and fetal genetic contributions and causal links between birth weight, blood pressure and glycemic traits.

Nicole M. Warrington
Robin N. Beaumont
Rachel M. Freathy
Research01 May 2019
Nature Genetics

Volume: 51, P: 804-814
Automatic Time/Response Records with Drosophila

G. A. WHEATLEY
J. A. HARDMAN
Research05 Mar 1960
Nature

Volume: 185, P: 708-709
Altered Antibody Isotype in Cystic Fibrosis: Impaired Natural Antibody Response to Polysaccharide Antigens

Richard B Moss
Yao-Pi Hsu
Gerda De Lange
Research01 Dec 1987
Pediatric Research

Volume: 22, P: 708-713
Original COVID-19 priming regimen impacts the immunogenicity of bivalent BA.1 and BA.5 boosters

Waning immunity and the emergence of the SARS-CoV-2 Omicron lineage led to reduced vaccine effectiveness and required vaccine updates. Here, the authors assess how different priming regimens affect the immunogenicity of BA.1 and BA.5 bivalent boosters.

Luca M. Zaeck
Ngoc H. Tan
Rory D. de Vries
ResearchOpen Access18 May 2024
Nature Communications

Volume: 15, P: 1-12
Breast cancer risk following Hodgkin lymphoma radiotherapy in relation to menstrual and reproductive factors

R Cooke
M E Jones
A J Swerdlow
ResearchOpen Access07 May 2013
British Journal of Cancer

Volume: 108, P: 2399-2406
Identification of tumour-associated and germ line p53 mutations in canine mammary cancer

N Veldhoen
J Watterson
J Milner
ResearchOpen Access10 Sept 1999
British Journal of Cancer

Volume: 81, P: 409-415
Enabling 3D CT-scanning of cultural heritage objects using only in-house 2D X-ray equipment in museums

Visualising the structure of museum objects is a crucial step in understanding the origin, state, and composition of cultural heritage artifacts. Here the authors present an approach for creating computed tomography reconstructions using only standard 2D radiography equipment already available in most larger museums.

Francien G. Bossema
Willem Jan Palenstijn
K. Joost Batenburg
ResearchOpen Access14 May 2024
Nature Communications

Volume: 15, P: 1-10
Determinants of epidemic size and the impacts of lulls in seasonal influenza virus circulation

Seasonal influenza levels were unusually low when non-pharmaceutical interventions for COVID-19 were in place. Here, the authors analyse serological and epidemiological evidence for the hypothesis that such lulls in influenza transmission lead to reduced immunity and therefore larger epidemics in subsequent seasons.

Simon P. J. de Jong
Zandra C. Felix Garza
Colin A. Russell
ResearchOpen Access18 Jan 2024
Nature Communications

Volume: 15, P: 1-11
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Breast cancer risk for BRCA1/BRCA2 mutation carriers varies depending on other genetic factors. Here, the authors perform a case-only genome-wide association study and highlight novel loci associated with breast cancer risk for BRCA1/BRCA2 mutation carriers.

Juliette Coignard
Michael Lush
Antonis C. Antoniou
ResearchOpen Access17 Feb 2021
Nature Communications

Volume: 12, P: 1-22
Explosive New Zealand mistletoe

Jenny J. Ladley
Dave Kelly
Research28 Dec 1995
Nature

Volume: 378, P: 766
Conducting tin halides with a layered organic-based perovskite structure

D. B. Mitzi
C. A. Feild
A. M. Guloy
Research09 Jun 1994
Nature

Volume: 369, P: 467-469
A surface antigenic marker for rat Schwann cells

J. P. BROCKES
K. L. FIELDS
M. C. RAFF
Research24 Mar 1977
Nature

Volume: 266, P: 364-366
β-Adrenoceptor activation mediates stress-induced secretion of β-endorphin-related peptides from intermediate but not anterior pituitary

F. Berkenbosch
F. J. H. Tilders
I. Vermes
Research15 Sept 1983
Nature

Volume: 305, P: 237-239
Subsequent female breast cancer risk associated with anthracycline chemotherapy for childhood cancer

In a pooled analysis of six international studies involving about 17,900 female survivors of childhood cancer, the use of doxorubicin was associated with a dose-dependent risk of subsequent breast cancer, irrespective of prior chest radiotherapy exposure.

Yuehan Wang
Cécile M. Ronckers
Jeanette F. Winther
ResearchOpen Access11 Sept 2023
Nature Medicine

Volume: 29, P: 2268-2277
Structure of the fibre-forming protein pilin at 2.6 Å resolution

Hans E. Parge
Katrina T. Forest
John A. Tainer
Research02 Nov 1995
Nature

Volume: 378, P: 32-38
Effect of β₂ microglobulin antibody on effector function of T-cell mediated cytotoxicity

JAMES J. LIGHTBODY
LENORE URBANI
M. D. POULIK
Research19 Jul 1974
Nature

Volume: 250, P: 227-228
Tamoxifen elevates transforming growth factor–β and suppresses diet–induced formation of lipid lesions in mouse aorta

David J. Grainger
Christine M. Witchell
James C. Metcalfe
Research01 Oct 1995
Nature Medicine

Volume: 1, P: 1067-1073
Genetic and environmental contributions to the link between synaesthesia and neurodevelopmental and psychiatric features: a twin study

Janina Neufeld
Tessa M. van Leeuwen
Mark J. Taylor
ResearchOpen Access12 Jul 2025
Translational Psychiatry

Volume: 15, P: 1-8
Flint Implements of Early Magdalenian Age from Deposits Underlying the Lower Estuarine Clay, Co. Antrim

J. P. T. BURCHELL
Research02 Dec 1933
Nature

Volume: 132, P: 860
Ureaplasma parvum and Ureaplasma urealyticum induce distinct types of inflammation in neonates and human epithelial cell models

Hongzhen Zhu
Pol Oliveras-Julià
Wendy W. J. Unger
ResearchOpen Access03 Oct 2025
Pediatric Research

P: 1-10
Viability criteria assessment during liver machine perfusion

Isabel M. A. Brüggenwirth
Vincent E. de Meijer
Paulo N. Martins
Research26 Oct 2020
Nature Biotechnology

Volume: 38, P: 1260-1262
Sequence polymorphism of HLA DRβ1 alleles relating to T-cell-recognized determinants

J. S. Cairns
J. M. Curtsinger
F. H. Bach
Research12 Sept 1985
Nature

Volume: 317, P: 166-168
Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

There are currently no drugs available to treat SARS-CoV-2 infection. A promising alternative treatment for COVID-19 patients is convalescent plasma. Here, Gharbharan et al. collect covalescent plasma and report no overall clinical benefit for 86 patients hospitalized for COVID-19 and treated with 300 mL convalescent plasma.

Arvind Gharbharan
Carlijn C. E. Jordans
Bart J. A. Rijnders
ResearchOpen Access27 May 2021
Nature Communications

Volume: 12, P: 1-12
What Abrogates Heart Transplant Rejection in Immunological Enhancement?

D. A. L. DAVIES
BARBARA J. ALKINS
Research01 Feb 1974
Nature

Volume: 247, P: 294-297
Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

Circulating metabolites reflect human health and disease. Here, Kettunen et al. perform a genome-wide association study on 123 circulating metabolic traits and identify novel genetic loci influencing systemic metabolism. They also link new molecular pathways with a known cardiovascular risk factor Lp(a).

Johannes Kettunen
Ayşe Demirkan
Mika Ala-Korpela
ResearchOpen Access23 Mar 2016
Nature Communications

Volume: 7, P: 1-9
Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription

Histone H3K4 methylation affects gene transcription from yeast to humans. Here, the authors show that Set1 and Jhd2, the only H3K4 methyltransferase and H3K4 demethylase, respectively, in budding yeast, co-regulate both positive and negative transcription mediated by nucleosomal turnover and occupancy.

Saravanan Ramakrishnan
Srijana Pokhrel
Mahesh B. Chandrasekharan
ResearchOpen Access21 Jun 2016
Nature Communications

Volume: 7, P: 1-16
wingless refines its own expression domain on the Drosophila wing margin

Eric J. Rulifson
Craig A. Micchelli
Seth S. Blair
Research07 Nov 1996
Nature

Volume: 384, P: 72-74
An empirical investigation of emotion and the criminal law: towards a “criminalization bias”?

Jozef N. Coppelmans
Fieke M. A. Wagemans
Lotte F. van Dillen
ResearchOpen Access15 Apr 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-17
Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients

Clinical studies have suggested that the therapeutic potential of polyclonal convalescent plasma is highest in the first days of symptoms. Here, the authors present results from a pooled analysis of two clinical trials in COVID-19 outpatients that did not provide conclusive evidence in favor of convalescent plasma.

Pere Millat-Martinez
Arvind Gharbharan
Michael Marks
ResearchOpen Access11 May 2022
Nature Communications

Volume: 13, P: 1-9
Germline mutations of the APC gene in Korean familial adenomatous polyposis patients

Yong-Jin Won
Kyu Joo Park
J.-G. Park
Research01 Mar 1999
Journal of Human Genetics

Volume: 44, P: 103-108
Second primary cancers in patients with cutaneous malignant melanoma: a population-based study in Sweden

C Wassberg
M Thörn
T Hakulinen
Research01 Jan 1996
British Journal of Cancer

Volume: 73, P: 255-259
70Z/3 Cbl induces PLCγ1 activation in T lymphocytes via an alternate Lat- and Slp-76-independent signaling mechanism

Laurie J Graham
Maria-Concetta Verí
Barbara Rellahan
Research25 Apr 2003
Oncogene

Volume: 22, P: 2493-2503
Lipid-dependent and phloretin-induced modifications of dipicrylamine adsorption by bilayer membranes

C.-C. WANG
L. J. BRUNER
Research16 Mar 1978
Nature

Volume: 272, P: 268-270
Pro-γ-melanocyte-stimulating hormone cleavage in adrenal gland undergoing compensatory growth

P. J. Lowry
L. Silas
F. E. Estivariz
Research03 Nov 1983
Nature

Volume: 306, P: 70-73
A sex difference in the human brain and its relation to transsexuality

Jiang-Ning Zhou
Michel A. Hofman
Dick F. Swaab
Research02 Nov 1995
Nature

Volume: 378, P: 68-70

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