Nature Search

Single-channel currents activated by light in Limulus ventral photoreceptors

Juan Bacigalupo
John E. Lisman
Research21 Jul 1983
Nature

Volume: 304, P: 268-270
Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation

Thomas O'Brien
Steven Hardin
John T. Lis
Research07 Jul 1994
Nature

Volume: 370, P: 75-77
How a gap junction maintains its structure

Jochen Braun
James R. Abney
John C. Owicki
Research26 Jul 1984
Nature

Volume: 310, P: 316-318
Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome

John A. McGrath
James R. McMillan
Robin A.J. Eady
Research01 Oct 1997
Nature Genetics

Volume: 17, P: 240-244
Transport of venusian rolling ‘stones’ by wind?

Ronald Greeley
John R. Marshall
Research28 Feb 1985
Nature

Volume: 313, P: 771-773
Immunological activity of covalently linked T-cell epitopes

Franceso Ria
Bosco M. C. Chan
Malcolm L. Gefter
Research25 Jan 1990
Nature

Volume: 343, P: 381-383
Intercalation of solid C60 with iodine

Qing Zhu
David E. Cox
Otto Zhou
Research20 Feb 1992
Nature

Volume: 355, P: 712-714
The δ- and ε-chains of the human T3/T-cell receptor complex are distinct polypeptides

Jannie Borst
John E. Coligan
Cox Terhorst
Research29 Nov 1984
Nature

Volume: 312, P: 455-458
Vibrational spectroscopy of superconducting K₃C₆₀ by inelastic neutron scattering

Kosmas Prassides
John Tomkinson
Robert C. Haddon
Research12 Dec 1991
Nature

Volume: 354, P: 462-463
Temporal Response of Immunoreactive Erythropoietin to Acute Hypoxemia in Fetal Sheep

John A Widness
Kari A Teramo
Robert Schwartz
Research01 Jan 1986
Pediatric Research

Volume: 20, P: 15-19
Community assessment of methods to deconvolve cellular composition from bulk gene expression

Deconvolution methods infer levels of immune infiltration from bulk expression of tumour samples. Here, authors assess 6 published and 22 community-contributed methods via a DREAM Challenge using in vitro and in silico transcriptional profiles of admixed cancer and healthy immune cells.

Brian S. White
Aurélien de Reyniès
Andrew J. Gentles
ResearchOpen Access27 Aug 2024
Nature Communications

Volume: 15, P: 1-22
Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB.1.16 infection in nonhuman primates

Seder and colleagues show that mucosal adenoviral-vectored vaccine boosting durably prevents infection in nonhuman primates of the highly transmissible, heterologous XBB.1.16 strain of SARS-CoV-2.

Matthew Gagne
Barbara J. Flynn
Robert A. Seder
ResearchOpen Access03 Sept 2024
Nature Immunology

Volume: 25, P: 1913-1927
Structural basis for CCR6 modulation by allosteric antagonists

Small molecule antagonists of CCR6 are potential drugs for autoimmune disorders. Here the authors present inactive structures of CCR6 bound by different allosteric antagonists from two series simultaneously, offering multiple approaches to inhibit CCR6.

David Jonathan Wasilko
Brian S. Gerstenberger
Huixian Wu
ResearchOpen Access31 Aug 2024
Nature Communications

Volume: 15, P: 1-13
Effect of ATP on actin filament stiffness

Paul A. Janmey
Soren Hvidt
John H. Hartwig
Research06 Sept 1990
Nature

Volume: 347, P: 95-99
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility

Large-scale sequence-based analyses identify novel risk variants and susceptibility genes for Crohn’s disease, and implicate mesenchymal cell-mediated intestinal homeostasis in disease etiology.

Aleksejs Sazonovs
Christine R. Stevens
Mark J. Daly
Research29 Aug 2022
Nature Genetics

Volume: 54, P: 1275-1283
Personalized, autologous neoantigen-specific T cell therapy in metastatic melanoma: a phase 1 trial

In this phase 1 trial of a personalized, neoantigen-specific autologous T cell therapy, BNT221, when given as monotherapy in patients with metastatic melanoma refractory to PD-1 and CTLA-4 inhibitor regimens, the therapy was safe and showed preliminary clinical activity and neoantigen-specific T cell responses.

Jessica S. W. Borgers
Divya Lenkala
Marit M. van Buuren
ResearchOpen Access03 Jan 2025
Nature Medicine

Volume: 31, P: 881-893
Complex gene conversion events in germline mutation at human minisatellites

Alec J. Jeffreys
Keiji Tamaki
John A.L. Armour
Research01 Feb 1994
Nature Genetics

Volume: 6, P: 136-145
Iron is prioritized to red blood cells over the brain in phlebotomized anemic newborn lambs

Tara G Zamora
Sixto F Guiang 3rd
Michael K Georgieff
Research11 Feb 2016
Pediatric Research

Volume: 79, P: 922-928
Microscopy with ultraviolet surface excitation for rapid slide-free histology

A slide-free, inexpensive and non-destructive microscopy technique rapidly provides high-resolution histology images that resemble those obtained from conventional haematoxylin-and-eosin-stained specimens.

Farzad Fereidouni
Zachary T. Harmany
Richard Levenson
Research04 Dec 2017
Nature Biomedical Engineering

Volume: 1, P: 957-966
Guide Swap enables genome-scale pooled CRISPR–Cas9 screening in human primary cells

Guide Swap challenges the hypothesis that Cas9–sgRNA binding is irreversible. The authors find that instead, nontargeting sgRNAs are swapped for targeting sgRNAs in the Cas9 complex. The method allows genome-scale functional screens in primary cells

Pamela Y. Ting
Albert E. Parker
Jennifer L. Snead
Research08 Oct 2018
Nature Methods

Volume: 15, P: 941-946
Circulatory and Metabolic Effects of Hypoxia in the Hyperinsulinemic Ovine Fetus

Barbara S Stonestreet
John A Widness
Dennis J Berard
Research01 Jul 1995
Pediatric Research

Volume: 38, P: 67-75
Expression of Pulmonary Metallothionein Genes in Late Gestational Lambs

Bruce R Pitt
Margaret A Brookens
John S Lazo
Research01 Oct 1992
Pediatric Research

Volume: 32, P: 424-430
mRNA-1273 protects against SARS-CoV-2 beta infection in nonhuman primates

The beta variant (B.1.351) is to date the most resistant to neutralization of the SARS-CoV-2 variants. Using nonhuman primates, Seder and colleagues demonstrate that double vaccination with a high dose of the lipid nanoparticle vaccine mRNA-1273 protects against infection with the beta variant.

Kizzmekia S. Corbett
Anne P. Werner
Robert A. Seder
Research20 Aug 2021
Nature Immunology

Volume: 22, P: 1306-1315
Obituary

JOHN COCKCROFT
Comments & Opinion15 Dec 1962
Nature

Volume: 196, P: 1037-1038
High resolution ancient sedimentary DNA shows that alpine plant diversity is associated with human land use and climate change

Here, the authors use sedimentary DNA, pollen, fungal spores, chironomids, and microcharcoal from an alpine lake core to reconstruct vegetation across 12,000 years. They find that vegetation responded to climate in the early Holocene, followed by a shift to human activity from 6000 years onward corresponding with an increase in deforestation and agropastoralism.

Sandra Garcés-Pastor
Eric Coissac
Inger Greve Alsos
ResearchOpen Access04 Nov 2022
Nature Communications

Volume: 13, P: 1-16
High-Frequency Oscillatory Ventilation Versus Intermittent Mandatory Ventilation: Early Hemodynamic Effects in the Premature Baboon with Hyaline Membrane Disease

John P Kinsella
Dale R Gerstmann
Robert A Delemos
Research01 Feb 1991
Pediatric Research

Volume: 29, P: 160-166
Induction of an Immunological Response in Local Lymph Nodes by Chemical Carcinogens

AUDREY FJELDE
J. L. TURK
Research20 Feb 1965
Nature

Volume: 205, P: 813-815
Prostaglandins in urine of foetal lambs

D. W. WALKER
M. D. MITCHELL
Research12 Jan 1978
Nature

Volume: 271, P: 161-162
MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus

Graham Anderson
Eric J. Jenkinson
John J. T. Owen
Research01 Mar 1993
Nature

Volume: 362, P: 70-73
HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

Janice M. Riberdy
John R. Newcomb
Peter Cresswell
Research03 Dec 1992
Nature

Volume: 360, P: 474-477
Formation of C₆₀ by pyrolysis of naphthalene

Roger Taylor
G. John Langley
David R. M. Walton
Research30 Dec 1993
Nature

Volume: 366, P: 728-731
Mouse model made

Karen Duff
John Hardy
News & Views09 Feb 1995
Nature

Volume: 373, P: 476-477
Relationship of a putative receptor protein kinase from maize to the S-locus glycoproteins of Brassica

John C. Walker
Ren Zhang
Research21 Jun 1990
Nature

Volume: 345, P: 743-746
Fullerenes in an impact crater on the LDEF spacecraft

Filippo Radicati di Brozolo
Theodore E. Bunch
John Macklin
Research05 May 1994
Nature

Volume: 369, P: 37-40
Synchronous changes in seawater strontium isotope composition and global climate

Steven C. Clemens
John W. Farrell
L. Peter Gromet
Research17 Jun 1993
Nature

Volume: 363, P: 607-610
A cGMP-gated cation channel in depolarizing photoreceptors of the lizard parietal eye

J. T. Finn
E. C. Solessio
K.-W. Yau
Research27 Feb 1997
Nature

Volume: 385, P: 815-819
Sedimentation rates, residence times and radionuclide inventories in Lake Baikal from ¹³⁷Cs and ²¹⁰Pb in sediment cores

David N. Edgington
J. Val Klump
Igor V. Sandimirov
Research18 Apr 1991
Nature

Volume: 350, P: 601-604
Early death due to defective neonatal lung liquid clearance in αENaC-deficient mice

Edith Hummler
Pierre Barker
Bernard C. Rossier
Research01 Mar 1996
Nature Genetics

Volume: 12, P: 325-328
Picosecond volume expansion drives a later-time insulator–metal transition in a nano-textured Mott insulator

During a photoinduced phase transition, electronic rearrangements are usually faster than lattice ones. Time-resolved measurements now show that the insulator-to-metal transition in a thin-film Mott insulator is preceded by lattice reconfiguration.

Anita Verma
Denis Golež
Andrej Singer
Research09 Feb 2024
Nature Physics

Volume: 20, P: 807-814
Effect of Chemical Sympathectomy on Myocardial Cell Division in the Newborn Rat

John D Kugler
Paul C Gillette
Howard K Thompson Jr.
Research01 Jul 1980
Pediatric Research

Volume: 14, P: 881-884
Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits

PrediXcan is a widely used gene expression imputation method that links genetic variants to gene expression. Here, the authors develop EpiXcan which leverages epigenetic annotations to inform transcriptomic imputation and further use the obtained gene-trait associations for computational drug repurposing.

Wen Zhang
Georgios Voloudakis
Panos Roussos
ResearchOpen Access23 Aug 2019
Nature Communications

Volume: 10, P: 1-13
Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme

Immunogenicity concerns preclude the use of bacterial kynureninases for cancer immunotherapy, while the human variant lacks the desired therapeutic effect. A human kynureninase enzyme has now been evolved to reach the activity and substrate specificity of its bacterial counterpart.

John Blazeck
Christos S. Karamitros
George Georgiou
Research19 Oct 2022
Nature Catalysis

Volume: 5, P: 952-967
Light emission based on nanophotonic vacuum forces

Vacuum fluctuations in the vicinity of nanophotonic structures can lead to the conversion of a free electron into a polariton and a high-energy photon, whose frequency can be controlled by the electromagnetic properties of the nanostructure.

Nicholas Rivera
Liang Jie Wong
Ido Kaminer
Research14 Oct 2019
Nature Physics

Volume: 15, P: 1284-1289
Revival of light signalling in the postmortem mouse and human retina

Experiments measuring light-evoked responses in postmortem mouse and human retinas are used to quantify decay of photoreceptors following death and optimise conditions for reviving trans-synaptic transmission.

Fatima Abbas
Silke Becker
Frans Vinberg
Research11 May 2022
Nature

Volume: 606, P: 351-357
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
RESPONSIVENESS AND SENSITIVITY TO INHALED NITRIC OXIDE CHANGES WITH AGE IN ISOLATED LUNGS OF DEVELOPING NEWBORN LAMBS. † 2059

Virginia A Powel
Gustavo A Moreira
John B Gordon
Research01 Apr 1996
Pediatric Research

Volume: 39, P: 346
EFFECT OF LUNG RECRUITMENT STRATEGIES ON GAS EXCHANGE AND LUNG INFLAMMATION IN SEVERE EXPERIMENTAL HYALINE MEMBRANE DISEASE. ♦ 1529

John P. Kinsella
Thomas A. Parker
Steven H. Abman
Research01 Apr 1997
Pediatric Research

Volume: 41, P: 257
HEMODYNAMIC CHANGES DURING BRIDGE OPENING IN VENO-ARTERIAL (VA) ECMO.316

Arno F Van Heijst
K. Djien Liem
Margot Van De Bor
Research01 Apr 1996
Pediatric Research

Volume: 39, P: 55
Measuring out-of-time-order correlations and multiple quantum spectra in a trapped-ion quantum magnet

Characterizing the correlations of quantum many-body systems is known to be hard, but there are ways around: for example, a new method for measuring out-of-time correlations demonstrated in a Penning trap quantum simulator with over 100 ions.

Martin Gärttner
Justin G. Bohnet
Ana Maria Rey
Research22 May 2017
Nature Physics

Volume: 13, P: 781-786
Control and readout of a superconducting qubit using a photonic link

High-fidelity control and readout of a superconducting qubit is performed with a low-noise optical fibre link that delivers microwave signals directly to the millikelvin quantum computing environment.

F. Lecocq
F. Quinlan
J. D. Teufel
Research24 Mar 2021
Nature

Volume: 591, P: 575-579

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