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Showing 151–200 of 200 results

Advanced filters: Author: JOSEPH SILK Clear advanced filters

Hypoxia induces heart regeneration in adult mice

A pathway triggered by chronic severe hypoxia boosts regeneration of injured hearts in adult mice.

Yuji Nakada
Diana C. Canseco
Hesham A. Sadek
Research31 Oct 2016
Nature

Volume: 541, P: 222-227
Regeneration and experimental orthotopic transplantation of a bioengineered kidney

Building on their earlier work on heart and lung organ engineering, Jeremy Song and his colleagues have now adapted the technology of using decellularized scaffolds to develop bioengineered kidneys for transplantation. When reseeded with endothelial and epithelial cells, and after orthotopic transplantation in rats, the grafts became perfused by the recipient's circulation, produced urine and provided clearance of metabolites.

Jeremy J Song
Jacques P Guyette
Harald C Ott
Research14 Apr 2013
Nature Medicine

Volume: 19, P: 646-651
New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut

Xiaoling Qiang
Anthony S. Liotta
Jesse Roth
ResearchOpen Access13 Nov 2017
npj Biofilms and Microbiomes

Volume: 3, P: 1-11
Simplified Surgical Placement and Stabilization Methods for Intracerebroventricular Cannulas in Rat Lateral Ventricles

David H. Jho BA
Herbert H. Engelhard MD, PhD, FACS
N. Joseph Espat MD, MS, FACS
Research01 Oct 2003
Lab Animal

Volume: 32, P: 43-48
Author Correction: T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

Katie J. Ewer
Jordan R. Barrett
Elizabeth Stafford
Amendments and Corrections21 May 2021
Nature Medicine

Volume: 27, P: 1116
The next decades for astronomy from the Moon

The far side of the Moon offers unique advantages for science. A meeting at the Royal Society in London brought together planetary scientists, astronomers, astrophysicists and other stakeholders to discuss the future of astronomy from the Moon.

Joseph Silk
Ian Crawford
John Zarnecki
News & Views20 Jun 2023
Nature Astronomy

Volume: 7, P: 648-650
Differential neurodegenerative phenotypes are associated with heterogeneous voiding dysfunction in a coronavirus-induced model of multiple sclerosis

Sanghee Lee
Balachandar Nedumaran
Anna P. Malykhina
ResearchOpen Access26 Jul 2019
Scientific Reports

Volume: 9, P: 1-11
Wound repair: the fibroblast and the inhibition of scar formation

I Grierson
J Joseph
J E Day
Research01 Mar 1988
Eye

Volume: 2, P: 135-148
Poldip2 knockdown inhibits vascular smooth muscle proliferation and neointima formation by regulating the expression of PCNA and p21

This study was designed to investigate the role of polymerase delta interacting protein 2 (Poldip2) in vascular smooth muscle proliferation and neointimal formation. Neointimal formation and proliferating cell nuclear antigen expression were inhibited in Poldip2+/- mice, in part due to induction of the cell cycle inhibitor p21.

Srinivasa Raju Datla
Lula L. Hilenski
Kathy K. Griendling
Research20 Sept 2018
Laboratory Investigation

Volume: 99, P: 387-398
Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network

Two papers show that Ampk and Sirt1 respond to metformin and resveratrol, respectively, in the duodenum to initiate a gut-brain-liver axis that reduces hepatic glucose production, thus explaining the antidiabetic actions of these two class of drugs.

Clémence D Côté
Brittany A Rasmussen
Tony K T Lam
Research06 Apr 2015
Nature Medicine

Volume: 21, P: 498-505
The myocardial regenerative potential of three-dimensional engineered cardiac tissues composed of multiple human iPS cell-derived cardiovascular cell lineages

Hidetoshi Masumoto
Takeichiro Nakane
Bradley B. Keller
ResearchOpen Access20 Jul 2016
Scientific Reports

Volume: 6, P: 1-10
Impact of Cell Composition and Geometry on Human Induced Pluripotent Stem Cells-Derived Engineered Cardiac Tissue

Takeichiro Nakane
Hidetoshi Masumoto
Bradley B. Keller
ResearchOpen Access03 Apr 2017
Scientific Reports

Volume: 7, P: 1-13
Knowing when to stop

When do we stop an ongoing science project to make room for something new? Decision-making is a complex process, ranging from budgetary considerations and tension between ongoing projects, to progress assessments and allowance for novel science developments.

Ofer Lahav
Joseph Silk
Comments & Opinion15 Sept 2021
Nature Astronomy

Volume: 5, P: 855-856
T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

A single dose of the ChAdOx1 nCoV-19 vaccine elicits antibodies and cytokine-producing T cells that might help control or prevent SARS-CoV-2 infection.

Katie J. Ewer
Jordan R. Barrett
Elizabeth Stafford
Research17 Dec 2020
Nature Medicine

Volume: 27, P: 270-278
A study of gene expression in the living human brain

Lora E. Liharska
You Jeong Park
Alexander W. Charney
ResearchOpen Access23 Aug 2025
Molecular Psychiatry

Volume: 31, P: 137-157
Evolutionary plasticity in nematode Hox gene complements and genomic loci arrangement

Joseph Kirangwa
Dominik R. Laetsch
Philipp Schiffer
ResearchOpen Access27 Nov 2024
Scientific Reports

Volume: 14, P: 1-13
Alteration of the PKC-mediated signaling pathway for smooth muscle contraction in obstruction-induced hypertrophy of the urinary bladder

Shaohua Chang
Joseph A Hypolite
Samuel Chacko
Research20 Apr 2009
Laboratory Investigation

Volume: 89, P: 823-832
Androgen receptor with short polyglutamine tract preferably enhances Wnt/β-catenin-mediated prostatic tumorigenesis

Yongfeng He
Jiaqi Mi
Zijie Sun
Research24 Feb 2020
Oncogene

Volume: 39, P: 3276-3291
Developmental stage of transplanted neural progenitor cells influences anatomical and functional outcomes after spinal cord injury in mice

In a mouse model of spinal cord injury, the developmental stage of transplanted neural progenitor cells is shown to influence anatomical and behavioral outcomes after spinal cord injury

Miriam Aceves
Ashley Tucker
Jennifer N. Dulin
ResearchOpen Access19 May 2023
Communications Biology

Volume: 6, P: 1-17
Our place in the Multiverse

Was the appearance of a Universe that can support life inevitable?

Joseph Silk
Books & Arts13 Sept 2006
Nature

Volume: 443, P: 145-146
Designing GLP-1 delivery: structural perspectives and formulation approaches for optimized therapy

Ravi Vamsi Peri
Harsh Anchan
Pardeep Gupta
ReviewsOpen Access23 Nov 2025
Nutrition & Diabetes

Volume: 15, P: 1-19
Transcriptional activators YAP/TAZ and AXL orchestrate dedifferentiation, cell fate, and metastasis in human osteosarcoma

Salah-Eddine Lamhamedi-Cherradi
Sana Mohiuddin
Joseph A. Ludwig
ResearchOpen Access06 Jan 2021
Cancer Gene Therapy

Volume: 28, P: 1325-1338
Iridescent biofilms of Cellulophaga lytica are tunable platforms for scalable, ordered materials

Claretta J. Sullivan
Kennedy Brown
Nancy Kelley-Loughnane
ResearchOpen Access14 Aug 2023
Scientific Reports

Volume: 13, P: 1-11
Changes in IGF-I and -II, IGF Binding Protein, and IGF Receptor Transcript Abundance after Uterine Artery Ligation

Wayne A Price
Liu Rong
A Joseph D'ercole
Research01 Sept 1992
Pediatric Research

Volume: 32, P: 291-295
Author Correction: Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

Jordan R. Barrett
Sandra Belij-Rammerstorfer
Dalila Zizi
Amendments and Corrections06 May 2021
Nature Medicine

Volume: 27, P: 1113
Glial responses to implanted electrodes in the brain

This Review discusses the role of glia as an effector of the performance and integration of devices implanted in the brain, and the implications of this for device development.

Joseph W. Salatino
Kip A. Ludwig
Erin K. Purcell
Reviews10 Nov 2017
Nature Biomedical Engineering

Volume: 1, P: 862-877
Activation of homology-directed DNA repair plays key role in CRISPR-mediated genome correction

Gourish Mondal
Caitlin J. VanLith
Joseph B. Lillegard
Research19 Oct 2022
Gene Therapy

Volume: 30, P: 386-397
Sarcomere dynamics revealed by a myofilament integrated FRET-based biosensor in live skeletal muscle fibers

Ashley A. Martin
Brian R. Thompson
Joseph M. Metzger
ResearchOpen Access27 Oct 2022
Scientific Reports

Volume: 12, P: 1-20
Increasing nitric oxide bioavailability fails to improve collateral vessel formation in humanized sickle cell mice

Sickle cell disease (SCD) is associated with deficits in revascularization following vascular injury and the role of nitric oxide (NO) bioavailability in SCD vasculopathies is controversial. This study tests L-arginine and NO-hydrogel treatments in a model of vascular insufficiency and finds that neither therapy improves recovery in SCD mice. In fact, delivery of NO at the site of ischemia increases oxidative stress and worsens outcomes, highlighting potential limitations of NO-targeted therapeutics in SCD.

Caitlin V. Lewis
Hassan Sellak
W. Robert Taylor
Research30 Mar 2022
Laboratory Investigation

Volume: 102, P: 805-813
Creation of stable water-free antibody based protein liquids

Antibodies are widely used in biotechnology and bioengineering, but are sensitive to their environment. Here, primary antibodies are converted into thermally-stable protein liquids, achieving >60% antigen binding after cyclic heating at 125 °C and remain active when incorporated into plastics.

Joseph M. Slocik
Patrick B. Dennis
Rajesh R. Naik
ResearchOpen Access20 Dec 2021
Communications Materials

Volume: 2, P: 1-11
Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis

Pragnya Das
Santosh K. Panda
Suchismita Acharya
ResearchOpen Access27 Feb 2019
Scientific Reports

Volume: 9, P: 1-12
Glucose Activates Vagal Control of Hyperglycemia and Inflammation in Fasted Mice

Biju Joseph
Guilherme Shimojo
Luis Ulloa
ResearchOpen Access30 Jan 2019
Scientific Reports

Volume: 9, P: 1-11
Integrated sensing and delivery of oxygen for next-generation smart wound dressings

Manuel Ochoa
Rahim Rahimi
Babak Ziaie
ResearchOpen Access18 May 2020
Microsystems & Nanoengineering

Volume: 6, P: 1-16
Reducing lung liquid volume in fetal lambs decreases ventricular constraint

Joseph J. Smolich
Michael M. H. Cheung
Jonathan P. Mynard
Research27 Jan 2021
Pediatric Research

Volume: 90, P: 795-800
Role of B Lymphocytes in New Bone Formation

Ana Marusic
Danka Grcevic
Joseph A Lorenzo
Research01 Nov 2000
Laboratory Investigation

Volume: 80, P: 1761-1774
Control of Western Corn Rootworm (Diabrotica virgifera virgifera) Reproduction through Plant-Mediated RNA Interference

Xiping Niu
Adane Kassa
Gusui Wu
ResearchOpen Access03 Oct 2017
Scientific Reports

Volume: 7, P: 1-13
Conditioned Contribution of Peripheral Cocaine Actions to Cocaine Reward and Cocaine-Seeking

Bin Wang
Zhi-Bing You
Roy A Wise
Research27 Mar 2013
Neuropsychopharmacology

Volume: 38, P: 1763-1769
Letter to the Editor: Amino Acid Metabolism in Dysmature Newborn Rats — Possible Explanation for the Antihypoglycemic Effect of Prenatal Glucocorticoids

Robert L Manniello
Joseph D Schulman
Philip M Farrell
Correspondence01 Nov 1977
Pediatric Research

Volume: 11, P: 1165-1166
Differential effects of Akt1 signaling on short- versus long-term consequences of myocardial infarction and reperfusion injury

Lining Ma
Bethany A Kerr
Payaningal R Somanath
Research21 Jul 2014
Laboratory Investigation

Volume: 94, P: 1083-1091
Metabolic and hormonal responses to exercise in the anti-obese Lou/C rats

K Couturier
S Servais
R Favier
Research22 Jun 2004
International Journal of Obesity

Volume: 28, P: 972-978
Production of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line system

Kathryn A. Hjerrild
Jing Jin
Simon J. Draper
ResearchOpen Access26 Jul 2016
Scientific Reports

Volume: 6, P: 1-15
Cellular regeneration strategies for macular degeneration: past, present and future

Valeria Chichagova
Dean Hallam
David H. Steel
ReviewsOpen Access05 Mar 2018
Eye

Volume: 32, P: 946-971
Nearby galaxies as pointers to a better theory of cosmic evolution

The relativistic Big Bang theory is a good description of our expanding Universe. But — as discussed in this review article — a still better theory would describe a mechanism by which matter is more rapidly gathered into galaxies and groups of galaxies, better fitting the observations.

P. J. E. Peebles
Adi Nusser
Reviews03 Jun 2010
Nature

Volume: 465, P: 565-569
Photovoltaic bioelectronics merging biology with new generation semiconductors and light in biophotovoltaics photobiomodulation and biosensing

Ebin Joseph
Manuela Ciocca
Thomas M. Brown
ReviewsOpen Access21 Nov 2024
npj Biosensing

Volume: 1, P: 1-44
The receptor for advanced glycation end products impairs collateral formation in both diabetic and non-diabetic mice

Laura M Hansen
Divya Gupta
W Robert Taylor
Research21 Nov 2016
Laboratory Investigation

Volume: 97, P: 34-42
Effects of Cocaine in Rats Exposed to Heroin

Francesco Leri
Joseph Flores
Jane Stewart
Research15 Jul 2003
Neuropsychopharmacology

Volume: 28, P: 2102-2116
Neural Correlates of Aggression in Medication-Naive Children with ADHD: Multivariate Analysis of Morphometry and Tractography

Jiook Cha
Tomer Fekete
Jonathan Posner
Research03 Feb 2015
Neuropsychopharmacology

Volume: 40, P: 1717-1725
Evidence for similar structural brain anomalies in youth and adult attention-deficit/hyperactivity disorder: a machine learning analysis

Yanli Zhang-James
Emily C. Helminen
Stephen V. Faraone
ResearchOpen Access01 Feb 2021
Translational Psychiatry

Volume: 11, P: 1-9
An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line

Yuwei Wang
Hui Xue
Yu-Zhuo Wang
Research12 Sept 2005
Laboratory Investigation

Volume: 85, P: 1392-1404
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

L Galluzzi
J M Bravo-San Pedro
G Kroemer
ReviewsOpen Access19 Sept 2014
Cell Death & Differentiation

Volume: 22, P: 58-73

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