Brain tumors may harbor small subpopulations of cells that share characteristics of neural stem cells. The use of neural stem cells and progenitor cells as delivery vehicles of molecules toxic to tumors offers a promising experimental treatment strategy. This Review summarizes recent advances in the basic understanding of neural stem cell and cancer-stem-cell biology and the progress towards translating these novel concepts into the clinic.
- Jörg Dietrich
- Jaime Imitola
- Santosh Kesari
